Patents by Inventor Claus Jochen Schmitges

Claus Jochen Schmitges has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Benzothia(oxa)diazol derivatives and their use as endothelin-receptor antagonists
    Patent number: 6197800
    Abstract: Novel compounds of the formula I in which R is X is O or S, and R1, R2, R3, R4, R5 and R6 have the meaning indicated in patent claim 1, or a tautomeric ring-closed form, and the (E) isomers and their salts exhibit endothelin receptor-antagonistic properties.
    Type: Grant
    Filed: March 27, 2000
    Date of Patent: March 6, 2001
    Assignee: Merck Patent Gesellschaft mi beschraenkter Haftung
    Inventors: Dieter Dorsch, Mathias Osswald, Werner Mederski, Claudia Wilm, Maria Christadler, Claus Jochen Schmitges
  • Endothelin receptor antagonists
    Patent number: 5883090
    Abstract: This invention relates to pyridizinone derivatives of formula I ##STR1## wherein the various substituents are defined in the specification, and salts thereof, which have useful pharmacological properties, in particular endothelin receptor-antagonistic properties. The compounds are thus useful for the treatment of illnesses associated with endothelin activities, such as hypertension, cardiac insufficiency, coronary heart disease, renal, cerebral and myocardial ischaemia, renal insufficiency, cerebral infarct, subarachnoid haemorrhage, arteriosclerosis pulmonary high blood pressure, inflammations, asthma, prostate hyperplasia, endotoxic shock and in complications after the administration of immunosuppressants which produce renal vasoconstriction.
    Type: Grant
    Filed: June 6, 1997
    Date of Patent: March 16, 1999
    Assignee: Merck Patent Gesellschaft mit Beschrankter Haftung
    Inventors: Dieter Dorsch, Mathias Osswald, Werner Mederski, Claudia Wilm, Claus Jochen Schmitges, Maria Christadler