Patents by Inventor Claus-Jugen Maier

Claus-Jugen Maier has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for the production of diarylcycloalkyl derivatives
    Patent number: 7803950
    Abstract: The invention relates generally to a process for preparing diarylcycloalkyl derivatives of the formula (I). wherein the respective R-group substituents are defined herein. These compounds of formula (I) are activators for peroxisome proliferator-activated receptors (PPAR activators) which are useful in the therapeutic treatment of a number of diseases and disorders of the central nervous system such as multiple sclerosis, Parkinson's Disease, psychiatric disorders and the like. The present invention is a novel process for preparing PPAR activators of the formula (I) which do not have the disadvantages of the processes known in the prior art. In particular, a process is provided with which the PPAR activators of formula (I) can be prepared in a suitable enantiomeric excess, i.e. high enantioselectivity, without the need for subsequent chiral chromatography.
    Type: Grant
    Filed: February 20, 2007
    Date of Patent: September 28, 2010
    Assignee: Sanofi-Aventis Deutschland GmbH
    Inventors: Christophe Salagnad, Frank Zocher, Andreas Burgard, Bernd Junker, Rolf Hoerlein, Thomas Stuedemann, Claus-Jügen Maier, Jochen Hachtel, Wolfgang Holla, Christoph Tappertzhofen, Berndt Kulitzscher, Stephane Mutti
  • NOVEL INTERMEDIATE COMPOUNDS USEFUL IN THE PRODUCTION OF DIARYLCYCLOALKYL DERIVATIVES
    Publication number: 20080051583
    Abstract: The invention relates generally to intermediate compounds derived during the process for preparing diarylcycloalkyl derivatives which are activators for peroxisome proliferator-activated receptors (PPAR activators) and are therefore useful in the therapeutic treatment of a number of diseases and disorders of the central nervous system such as multiple sclerosis, Parkinson's Disease, psychiatric disorders and the like. The intermediate compounds of the present invention are defined structurally by the formulae (Ia): and formula (II): wherein the respective substituent groups are defined herein.
    Type: Application
    Filed: October 31, 2007
    Publication date: February 28, 2008
    Applicant: SANOFI-AVENTIS DEUTSCHLAND GMBH
    Inventors: Christophe Salagnad, Frank Zocher, Andreas Burgard, Bernd Junker, Rolf Hoerlein, Thomas Stuedemann, Claus-Jugen Maier, Jochen Hachtel, Wolfgang Holla, Christoph Tappertzhofen, Berndt Kulitzscher, Stephane Mutti
  • METHOD FOR THE PRODUCTION OF DIARYLCYCLOALKYL DERIVATIVES
    Publication number: 20070197614
    Abstract: The invention relates generally to a process for preparing diarylcycloalkyl derivatives of the formula (I). wherein the respective R-group substituents are defined herein. These compounds of formula (I) are activators for peroxisome proliferator-activated receptors (PPAR activators) which are useful in the therapeutic treatment of a number of diseases and disorders of the central nervous system such as multiple sclerosis, Parkinson's Disease, psychiatric disorders and the like. The present invention is a novel process for preparing PPAR activators of the formula (I) which do not have the disadvantages of the processes known in the prior art. In particular, a process is provided with which the PPAR activators of formula (I) can be prepared in a suitable enantiomeric excess, i.e. high enantioselectivity, without the need for subsequent chiral chromatography.
    Type: Application
    Filed: February 20, 2007
    Publication date: August 23, 2007
    Applicant: SANOFI-AVENTIS DEUTSCHLAND GMBH
    Inventors: Christophe Salagnad, Frank Zocher, Andreas Burgard, Bernd Junker, Rolf Hoerlein, Thomas Stuedemann, Claus-Jugen Maier, Jochen Hachtel, Wolfgang Holla, Christoph Tappertzhofen, Berndt Kulitzscher, Stephane Mutti