Patents by Inventor Claus Knippschild
Claus Knippschild has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Publication number: 20230001410Abstract: The present disclosure relates to a lid for a microtiter plate, which has a plurality of cavities arranged on a top of the microtiter plate and serve for receiving samples, wherein the lid is securable on the microtiter plate such that it covers of the microtiter plate. The lid has a basic body, which is embodied such that at least in regions, which are located above the cavities when the lid is on the microtiter plate, it is transmissive for light of predeterminable wavelength, and wherein the lid includes at least one closure element, which is embodied and/or arranged in such a manner that it closes at least one of the cavities in the microtiter plate when the lid is on the microtiter plate.Type: ApplicationFiled: November 28, 2019Publication date: January 5, 2023Inventors: Claus Knippschild, Jan Kaiser, Robert Möller, Christian Paulenz
-
Publication number: 20220054677Abstract: A UV module for deactivating biologically contaminated surfaces in an interior of a device includes: a carrier; a radiation source affixed to the carrier and configured to emit UV radiation; and a control unit connected to the radiation source, wherein the control unit is configured to receive and process at least one information item to activate the radiation source to emit UV radiation based on the at least one information item. A system comprises such a UV module wherein the device is configured for the handling and/or examination of samples comprising biological material and has an interior into which the UV module can be introduced. A method for deactivating biologically contaminated surfaces in an interior of a device for the handling and/or examination of samples comprising biological material includes using the device.Type: ApplicationFiled: August 19, 2021Publication date: February 24, 2022Inventors: Thomas Moore, Claus Knippschild, Martin Hentschel
-
Publication number: 20220054960Abstract: Disclosed is a filtering method for isolating a substance from a sample. The method includes: providing a filter module having a sample inlet, a sample outlet, and a filter covering the sample outlet; introducing, via a sample inlet a first quantity of the sample into the filter module; conducting the sample from the sample inlet through the filter and the sample outlet by applying a pressure difference between a side of the filter facing the sample inlet and a side of the filter facing away from the sample inlet; measuring the pressure difference and/or a volumetric flow through the filter; comparing the measurement values to a predefined reference value; and ending the method if successively detected measurement values lie within a predefined range of values around the reference value. Disclosed also is a device with which the method can be carried out.Type: ApplicationFiled: November 28, 2019Publication date: February 24, 2022Inventors: Christian Paulenz, Robert Möller, Claus Knippschild
-
Publication number: 20220023868Abstract: The present invention relates to an apparatus (1) for controlling the temperature of a sample carrier (2), and to an automatable laboratory workplace comprising an apparatus (1) according to the invention. The apparatus comprises a heating device (2) having a heater (3) and a movable heating cover (6), which is arranged over the receiving region of the heater (3) and is designed to press the sample carrier (4) in a heating position (H) into the receiving region (3a) of the heater (3) with a predefinable contact pressure, and a transport device (8), which is designed to introduce the sample carrier (3) into the apparatus (1) from an insertion position (E) outside the apparatus (1).Type: ApplicationFiled: November 28, 2019Publication date: January 27, 2022Inventors: Claus Knippschild, Jan Kaiser, Robert Möller, Christian Paulenz
-
Patent number: 10898901Abstract: A temperature-control device for receiving a reaction vessel having a heat-insulated interior space and which is covered by a lid. The reaction vessel has a hollow body and a cap, this hollow body being closed on one side by a base. The base contacts a heatable heating block in order to heat a sample located in the reaction vessel. The hollow body is surrounded by a heatable heating body which communicates with the lid via a heat-conducting contact region so that the heating body heats the hollow body directly and heats the cap indirectly via the lid.Type: GrantFiled: December 5, 2016Date of Patent: January 26, 2021Assignee: Analytik Jena AGInventors: Claus Knippschild, Robert Moeller
-
Publication number: 20200149030Abstract: The invention relates to a mobile device system, comprising a hand-held device and a test kit for the mobile isolation of nucleic acids. The hand-held device comprises at least one sample block for inserting sample containers, a sample block holder with boreholes or recesses for accommodating the sample blocks, a device base with electronic control units for the sample blocks, a voltage source and a connection to the sample block holder, as well as a test kit for the isolation of nucleic acids. The hand-held device is characterized in that the sample blocks can be removed from the sample block holder and the sample block holder can be removed from the device base.Type: ApplicationFiled: January 9, 2020Publication date: May 14, 2020Applicant: AJ Innuscreen GmbHInventors: Timo HILLEBRAND, Claus KNIPPSCHILD
-
Publication number: 20180361387Abstract: A temperature-control device for receiving a reaction vessel having a heat-insulated interior space and which is covered by a lid. The reaction vessel has a hollow body and a cap, this hollow body being closed on one side by a base. The base contacts a heatable heating block in order to heat a sample located in the reaction vessel. The hollow body is surrounded by a heatable heating body which communicates with the lid via a heat-conducting contact region so that the heating body heats the hollow body directly and heats the cap indirectly via the lid.Type: ApplicationFiled: December 5, 2016Publication date: December 20, 2018Inventors: Claus KNIPPSCHILD, Robert MOELLER
-
Patent number: 10107740Abstract: Cuvette, comprising a first flat plate (1) and a second flat plate (2), both of which in a closed state of the cuvette are positioned so as to be situated opposite parallel to each other and at which there is at least one transparent first measuring surface (1.1) and at least one transparent second measuring surface (2.1), which define in pairs a measuring space (3), in which a liquid sample solution having a drop volume can be held by means of its surface tension and capillary forces. At least the second measuring surface (2.1) of each one of the measuring spaces (3) is a stepped surface, which has at least two plane-parallel partial measuring surfaces (2.1.1, 2.1.2), which are connected to each other by means of a setting surface (2.1.0), so that the partial measuring surfaces (2.1.1, 2.1.2) exhibit different vertical distances (b1, b2) from the first measuring surface (1.1).Type: GrantFiled: December 22, 2016Date of Patent: October 23, 2018Assignee: Analytik Jena AGInventors: Thomas Moore, Claus Knippschild, Martin Hentschel
-
Publication number: 20170327816Abstract: The invention relates to a mobile device system, comprising a hand-held device and a test kit for the mobile isolation of nucleic acids. The hand-held device comprises at least one sample block for inserting sample containers, a sample block holder with boreholes or recesses for accommodating the sample blocks, a device base with electronic control units for the sample blocks, a voltage source and a connection to the sample block holder, as well as a test kit for the isolation of nucleic acids. The hand-held device is characterized in that the sample blocks can be removed from the sample block holder and the sample block holder can be removed from the device base.Type: ApplicationFiled: December 23, 2016Publication date: November 16, 2017Applicant: AJ INNUSCREEN GmbHInventors: Timo Hillebrand, Claus Knippschild
-
Publication number: 20170184489Abstract: Cuvette, comprising a first flat plate (1) and a second flat plate (2), both of which in a closed state of the cuvette are positioned so as to be situated opposite parallel to each other and at which there is at least one transparent first measuring surface (1.1) and at least one transparent second measuring surface (2.1), which define in pairs a measuring space (3), in which a liquid sample solution having a drop volume can be held by means of its surface tension and capillary forces. At least the second measuring surface (2.1) of each one of the measuring spaces (3) is a stepped surface, which has at least two plane-parallel partial measuring surfaces (2.1.1, 2.1.2), which are connected to each other by means of a setting surface (2.1.0), so that the partial measuring surfaces (2.1.1, 2.1.2) exhibit different vertical distances (b1, b2) from the first measuring surface (1.1).Type: ApplicationFiled: December 22, 2016Publication date: June 29, 2017Inventors: Thomas MOORE, Claus KNIPPSCHILD, Martin HENTSCHEL
-
Patent number: 9399793Abstract: The invention relates to a device that allows a target nucleic acid to be detected in a homogeneous batch using two different detection formats. The device comprises at least two heatable sample blocks and a reaction cartridge which contains a base (1, 15) and at least one film (3, 4) sealing the base (1, 15), wherein the film (3, 4) comprises a surface (13, 14) that is not connected to the base (1, 15) and said surface (13, 14) forms a volume (16) for media transfer or at least one reaction chamber (10). The device can be used in particular for mobile gene diagnostics under field conditions.Type: GrantFiled: April 8, 2011Date of Patent: July 26, 2016Assignee: AJ Innuscreen GmbHInventors: Timo Hillebrand, Claus Knippschild, Elmara Graser
-
Patent number: 9260750Abstract: A mobile rapid test system for nucleic acid analysis. A method comprising the steps of amplification of the nucleic acids by means of rapid-PCR technology, conversion of a double-stranded amplification product into a single-stranded DNA fragment, hybridization with a labeled probe and detection of the nucleic acids on a lateral-flow test strip. A device comprising a reaction cavity which preferably consists of a thin film, inlet and outlet openings for the reaction cavity, one or more heatable sample blocks which are connected to miniaturized cooling bodies and a window for reading off the result. The lateral-flow test strip is a component of the mobile rapid test system. Operation of the instrument system requires no external power source, but only batteries or a rechargeable battery.Type: GrantFiled: December 21, 2012Date of Patent: February 16, 2016Assignee: AJ INNUSCREEN, GmbHInventors: Timo Hillebrand, Claus Knippschild, Benjamin Jaschinsky, Elmara Graser
-
Patent number: 9140634Abstract: A heating and magnet module for a device for the purpose of purifying nucleic acids, having a plate assembly which has a heating plate, and a magnet carrier plate. The heating plate and the magnet carrier plate can be moved vertically relative to each other between two end positions, in opposition to a spring force. A vessel arrangement is placed on the heating plate, having row or matrix form vessels. One magnet of the magnet carrier plate is functionally assigned to each of these.Type: GrantFiled: September 9, 2014Date of Patent: September 22, 2015Assignee: Analytik Jena AGInventors: Claus Knippschild, Claudia Schiessl
-
Publication number: 20130157348Abstract: The invention relates to a device that allows a target nucleic acid to be detected in a homogeneous batch using two different detection formats. The device comprises at least two heatable sample blocks and a reaction cartridge which contains a base (1, 15) and at least one film (3, 4) sealing the base (1, 15), wherein the film (3, 4) comprises a surface (13, 14) that is not connected to the base (1, 15) and said surface (13, 14) forms a volume (16) for media transfer or at least one reaction chamber (10). The device can be used in particular for mobile gene diagnostics under field conditions.Type: ApplicationFiled: April 8, 2011Publication date: June 20, 2013Applicant: aj Innuscreen GmbHInventors: Timo Hillebrand, Claus Knippschild, Elmara Graser
-
Publication number: 20130130257Abstract: A mobile rapid test system for nucleic acid analysis. A method comprising the steps of amplification of the nucleic acids by means of rapid-PCR technology, conversion of a double-stranded amplification product into a single-stranded DNA fragment, hybridization with a labeled probe and detection of the nucleic acids on a lateral-flow test strip. A device comprising a reaction cavity which preferably consists of a thin film, inlet and outlet openings for the reaction cavity, one or more heatable sample blocks which are connected to miniaturized cooling bodies and a window for reading off the result. The lateral-flow test strip is a component of the mobile rapid test system. Operation of the instrument system requires no external power source, but only batteries or a rechargeable battery.Type: ApplicationFiled: December 21, 2012Publication date: May 23, 2013Inventors: Timo Hillebrand, Claus Knippschild, Benjamin Jaschinsky, Elmara Graser
-
Publication number: 20110091879Abstract: The invention relates to a mobile device system, comprising a hand-held device and a test kit for the mobile isolation of nucleic acids. The hand-held device comprises at least one sample block for inserting sample containers, a sample block holder with boreholes or recesses for accommodating the sample blocks, a device base with electronic control units for the sample blocks, a voltage source and a connection to the sample block holder, as well as a test kit for the isolation of nucleic acids. The hand-held device is characterized in that the sample blocks can be removed from the sample block holder and the sample block holder can be removed from the device base.Type: ApplicationFiled: August 16, 2010Publication date: April 21, 2011Applicant: AJ INNUSCREEN GmbHInventors: Timo HILLEBRAND, Claus KNIPPSCHILD, Benjamin JASCHINSKY
-
Publication number: 20110039261Abstract: A mobile rapid test system for nucleic acid analysis. A method comprising the steps of amplification of the nucleic acids by means of rapid-PCR technology, conversion of a double-stranded amplification product into a single-stranded DNA fragment, hybridization with a labeled probe and detection of the nucleic acids on a lateral-flow test strip. A device comprising a reaction cavity which preferably consists of a thin film, inlet and outlet openings for the reaction cavity, one or more heatable sample blocks which are connected to miniaturized cooling bodies and a window for reading off the result. The lateral-flow test strip is a component of the mobile rapid test system. Operation of the instrument system requires no external power source, but only batteries or a rechargeable battery.Type: ApplicationFiled: June 22, 2010Publication date: February 17, 2011Applicant: AJ INNUSCREEN GmbHInventors: Timo Hillebrand, Claus Knippschild, Benjamin Jaschinsky, Elmara Graser