Patents by Inventor Claus Krebber

Claus Krebber has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS CONTAINING ACTIVATABLE ANTIBODIES
    Publication number: 20210317188
    Abstract: The invention provides a composition including an intact activatable antibody and a clipped variant thereof, methods of separating clipped variants of intact activatable antibodies from intact activatable antibodies and related methods including methods for determining or monitoring a relative percentage of an activatable antibody and a clipped variant thereof during a composition production process.
    Type: Application
    Filed: April 9, 2021
    Publication date: October 14, 2021
    Applicant: CytomX Therapeutics, Inc.
    Inventors: Sarah PATRICK, Claus KREBBER, Sridhar VISWANATHAN, Shanti Gonela DUVUR, Eric URENO
  • POLYPEPTIDE INHIBITORS OF VLA4
    Publication number: 20120135912
    Abstract: The invention provides novel 2D-VCAM-1 variant polypeptides and conjugates thereof that bind human VLA4. The invention also provides related polynucleotides, compositions, vectors, host cells, and methods.
    Type: Application
    Filed: May 10, 2011
    Publication date: May 31, 2012
    Applicant: PERSEID THERAPEUTICS LLC
    Inventors: MADAN M. PAIDHUNGAT, AMULYA NANISETTI, THOMAS BOUQUIN, KIM VILBOUR ANDERSEN, STEVEN J. CHAPIN, CLAUS KREBBER, RONG A. FAN, DANIEL MALASHOCK, AMY BRIDEAU-ANDERSEN, ERIK KARRER, BRUCE DEVENS, STEVEN H. BASS
  • High throughput mass spectrometry
    Patent number: 7384387
    Abstract: Apparatus and methods for high throughput mass spectrometry are provided. The methods involve sample preparation in an off-line parallel purification system. Such methods include but are not limited to the use of an appropriate buffer when generating samples or the use of a solid support for tagged components. The samples prepared in this way do not then need to be column separated. The apparatus provided includes a cell growth plate for growing cells and generating products and/or reactants, an off-line parallel purification system, a mass spectrometer, and an automatic sampler that transports samples and injects them into the mass spectrometer of the apparatus. The methods and apparatus described are used, for example, in screening enzyme reaction pathways.
    Type: Grant
    Filed: February 11, 2000
    Date of Patent: June 10, 2008
    Assignee: Maxygen, Inc.
    Inventors: Sun Ai Raillard, Yong Hong Chen, Claus Krebber, Jeremy Minshull, Willem P. C. Stemmer
  • IN-SOLUTION ACTIVATION OF FACTOR VII
    Publication number: 20070129298
    Abstract: The present invention is directed to a method for activation of Factor VII to FVIIa in solution.
    Type: Application
    Filed: July 21, 2006
    Publication date: June 7, 2007
    Inventors: Claus Krebber, Sridhar Viswanathan
  • Evolution of whole cells and organisms by recursive sequence recombination
    Publication number: 20070048775
    Abstract: The invention provides methods employing iterative cycles of recombination and selection/screening for evolution of whole cells and organisms toward acquisition of desired properties. Examples of such properties include enhanced recombinogenicity, genome copy number, and capacity for expression and/or secretion of proteins and secondary metabolites.
    Type: Application
    Filed: August 17, 2006
    Publication date: March 1, 2007
    Inventors: Stephen Cardayre, Matthew Tobin, Willem Stemmer, Jon Ness, Jeremy Minshull, Phillip Patten, Venkiteswaran Subramanian, Linda Castle, Claus Krebber, Steven Bass, Ying-Xin Zhang, Tony Cox, Gjalt Huisman, Ling Yuan, Joseph Affholter
  • Evolution of whole cells and organisms by recursive sequence recombination
    Publication number: 20070026446
    Abstract: The invention provides methods employing iterative cycles of recombination and selection/screening for evolution of whole cells and organisms toward acquisition of desired properties. Examples of such properties include enhanced recombinogenicity, genome copy number, and capacity for expression and/or secretion of proteins and secondary metabolites.
    Type: Application
    Filed: August 17, 2006
    Publication date: February 1, 2007
    Inventors: Stephen del Cardayre, Matthew Tobin, Willem Stemmer, Jon Ness, Jeremy Minshull, Phillip Patten, Venkiteswaran Subramanian, Linda Castle, Claus Krebber, Steven Bass, Ying-Xin Zhang, Tony Cox, Gjalt Huisman, Ling Yuan, Joseph Affholter
  • Biosensors, reagents and diagnostic applications of directed evolution
    Publication number: 20020127623
    Abstract: Methods for sensing test stimuli using arrays of biopolymers are provided. Libraries of biopolymers, such nucleic acid variants, and expression products encoded by nucleic acid variants are provided. Reusable library arrays, and methods for their use are provided.
    Type: Application
    Filed: July 31, 2001
    Publication date: September 12, 2002
    Applicant: Maxygen, Inc.
    Inventors: Jeremy Minshull, S. Christopher Davis, Mark Welch, Sun Ai Raillard, Kurt Vogel, Claus Krebber