Patents by Inventor Claus Marquordt
Claus Marquordt has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11583852Abstract: There is provided a connecting interface for fluidically interconnecting microfluidic channels. The connecting interface comprises one or more substrates which collectively define a first microfluidic channel which includes a connecting region for fluidically connecting the first microfluidic channel to a second microfluidic channel. The connecting interface further comprises at least one slit in an outer surface of one of the one or more substrates, wherein the at least one slit provides a fluid passage from the outer surface to the connecting region of the first microfluidic channel, and the at least one slit has at least one dimension extending beyond the connecting region along a direction parallel to the outer surface.Type: GrantFiled: May 22, 2019Date of Patent: February 21, 2023Assignee: miDiagnostics NVInventors: Benjamin Jones, Peter Peumans, Claus Marquordt, Remus Brix Anders Haupt
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Publication number: 20200180963Abstract: A method of forming a 3D graphene material adhered to a surface of a substrate comprises: providing a carbon source on the surface of the substrate; and exposing at least a portion of the carbon source and/or at least a portion of the substrate to a laser beam, thereby converting at least a portion of the carbon source into a 3D graphene material adhered to the surface of the substrate.Type: ApplicationFiled: August 24, 2018Publication date: June 11, 2020Applicant: RD GRAPHENE LIMITEDInventors: Marco Caffio, Claus Marquordt
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Patent number: 10509032Abstract: An assay method and device can perform at least one (e.g., at least two) assays on a single aliquot of a sample liquid. The device can mix a sample liquid with assay reagents including magnetically susceptible particles. The device is configured to create a sample liquid-air interface with the sample liquid. The magnetically susceptible particles can be located (via an applied magnetic field) at the liquid-air interface when a second liquid contacts the interface to form a liquid-liquid interface. The magnetic particles travel across the liquid-liquid interface to the second liquid. The magnetically susceptible particles are configured to trans-port an analyte across the interface into the second liquid. An assay for the analyte is performed in the second liquid. An assay for another analyte can also be performed in the sample liquid.Type: GrantFiled: February 27, 2017Date of Patent: December 17, 2019Assignee: ALERE SWITZERLAND GMBHInventors: Phillip Lowe, Steven Alexander Keatch, Steven Howell, Claus Marquordt, Ruth Polwart, Alan Kenneth Thomson
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Publication number: 20190358631Abstract: There is provided a connecting interface for fluidically interconnecting microfluidic channels. The connecting interface comprises one or more substrates which collectively define a first microfluidic channel which includes a connecting region for fluidically connecting the first microfluidic channel to a second microfluidic channel. The connecting interface further comprises at least one slit in an outer surface of one of the one or more substrates, wherein the at least one slit provides a fluid passage from the outer surface to the connecting region of the first microfluidic channel, and the at least one slit has at least one dimension extending beyond the connecting region along a direction parallel to the outer surface.Type: ApplicationFiled: May 22, 2019Publication date: November 28, 2019Inventors: Benjamin Jones, Peter Peumans, Claus Marquordt, Remus Brix Anders Haupt
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Publication number: 20180059105Abstract: An assay method and device can perform at least one (e.g., at least two) assays on a single aliquot of a sample liquid. The device can mix a sample liquid with assay reagents including magnetically susceptible particles. The device is configured to create a sample liquid-air interface with the sample liquid. The magnetically susceptible particles can be located (via an applied magnetic field) at the liquid-air interface when a second liquid contacts the interface to form a liquid-liquid interface. The magnetic particles travel across the liquid-liquid interface to the second liquid. The magnetically susceptible particles are configured to trans-port an analyte across the interface into the second liquid. An assay for the analyte is performed in the second liquid. An assay for another analyte can also be performed in the sample liquid.Type: ApplicationFiled: February 27, 2017Publication date: March 1, 2018Applicant: INVERNESS MEDICAL SWITZERLAND GMBHInventors: Phillip Lowe, Steven Alexander Keatch, Steven Howell, Claus Marquordt, Ruth Polwart, Alan Kenneth Thomson
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Patent number: 9618506Abstract: An assay method and device can perform at least one (e.g., at least two) assays on a single aliquot of a sample liquid. The device can mix a sample liquid with assay reagents including magnetically susceptible particles. The device is configured to create a sample liquid-air interface with the sample liquid. The magnetically susceptible particles can be located (via an applied magnetic field) at the liquid-air interface when a second liquid contacts the interface to form a liquid-liquid interface. The magnetic particles travel across the liquid-liquid interface to the second liquid. The magnetically susceptible particles are configured to transport an analyte across the interface into the second liquid. An assay for the analyte is performed in the second liquid. An assay for another analyte can also be performed in the sample liquid.Type: GrantFiled: March 29, 2007Date of Patent: April 11, 2017Assignee: INVERNESS MEDICAL SWITZERLAND GMBHInventors: Phillip Lowe, Steven Alexander Keatch, Steven Howell, Claus Marquordt, Ruth Polwart, Alan Kenneth Thomson
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Patent number: 9063132Abstract: An assay method and device can perform at least one (e.g., at least two) assays on a single aliquot of a sample liquid. The device can mix a sample liquid with assay reagents including magnetically susceptible particles. The device is configured to create a sample liquid-air interface with the sample liquid. The magnetically susceptible particles can be located (via an applied magnetic field) at the liquid-air interface when a second liquid contacts the interface to form a liquid-liquid interface. The magnetic particles travel across the liquid:liquid interface to the second liquid. The magnetically susceptible particles are configured to transport an analyte across the interface into the second liquid. An assay for the analyte is performed in the second liquid. An assay for another analyte can also be performed in the sample liquid.Type: GrantFiled: April 2, 2010Date of Patent: June 23, 2015Assignee: INVERNESS MEDICAL SWITZERLAND GMBHInventors: John William Dilleen, Phillip Lowe, Ruth Polwart, Jennifer Hay, Claus Marquordt, Steven Alexander Keatch, Steven Howell, Alan Thomson
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Publication number: 20110088786Abstract: A method for manipulating a first liquid within a device including fabricated microstructures for transporting the first liquid through a system of capillary channels and cavities with a closed configuration. The method including transporting the first liquid through the system by capillary force only, stopping a flow of the first liquid temporarily at a capillary stop, switching on the flow of the first liquid after a desired stop time is elapsed, adjusting the stop time of the first liquid by a length and a cross-section of the control capillary between a beginning of the control capillary and its end at the capillary stop, metering the first liquid to be manipulated, and holding a metered amount of the first liquid during the stop time within a cavity.Type: ApplicationFiled: December 23, 2010Publication date: April 21, 2011Applicant: Boehringer Ingelheim microParts GmbHInventors: Gert BLANKENSTEIN, Thomas Willms, Ralf-Peter Peters, Claus Marquordt, Holger Bartos
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Publication number: 20110053289Abstract: An assay method and device can perform at least one (e.g., at least two) assays on a single aliquot of a sample liquid. The device can mix a sample liquid with assay reagents including magnetically susceptible particles. The device is configured to create a sample liquid-air interface with the sample liquid. The magnetically susceptible particles can be located (via an applied magnetic field) at the liquid-air interface when a second liquid contacts the interface to form a liquid-liquid interface. The magnetic particles travel across the liquid-liquid interface to the second liquid. The magnetically susceptible particles are configured to trans-port an analyte across the interface into the second liquid. An assay for the analyte is performed in the second liquid. An assay for another analyte can also be performed in the sample liquid.Type: ApplicationFiled: March 29, 2007Publication date: March 3, 2011Applicant: INVERNESS MEDICAL SWITZERLAND GMBHInventors: Phillip Lowe, Steven Alexander Keatch, Steven Howell, Claus Marquordt, Ruth Polwart, Alan Kenneth Thomson
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Publication number: 20110008813Abstract: An assay method and device can perform at least one (e.g., at least two) assays on a single aliquot of a sample liquid. The device can mix a sample liquid with assay reagents including magnetically susceptible particles. The device is configured to create a sample liquid-air interface with the sample liquid. The magnetically susceptible particles can be located (via an applied magnetic field) at the liquid-air interface when a second liquid contacts the interface to form a liquid-liquid interface. The magnetic particles travel across the liquid:liquid interface to the second liquid. The magnetically susceptible particles are configured to transport an analyte across the interface into the second liquid. An assay for the analyte is performed in the second liquid. An assay for another analyte can also be performed in the sample liquid.Type: ApplicationFiled: April 2, 2010Publication date: January 13, 2011Applicant: Inverness Medical Switzerland GMBHInventors: John William Dilleen, Phillip Lowe, Ruth Polwart, Jennifer Hay, Claus Marquordt, Steven Alexander Keatch, Steven Howell, Alan Thompson
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Patent number: 7485118Abstract: The present invention relates to a microstructure arrangement for the bubble-free filling with a liquid of at least one system for draining off liquids. The arrangement has an inlet for the arrangement to be connected to a system for the supply of liquids and at least one outlet for the arrangement to be connected to the at least one liquid-discharging system. The arrangement has a transition region, through which the liquid can be transported from the inlet to the at least one outlet. At a start of the transition region, at least one first microstructure element for producing a point with increased capillary force is provided, in order to achieve gap-free wetting of the areas bounding this point with increased capillary force, in particular side walls, a cover and/or a bottom.Type: GrantFiled: December 20, 2004Date of Patent: February 3, 2009Assignee: Boehringer Ingelholm Microparts GmbHInventors: Gert Blankenstein, Ralf-Peter Peters, Claus Marquordt
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Patent number: 7134453Abstract: The invention relates to a microfluidic switch for stopping a liquid flow during a time interval with the following features: the switch has at least one first channel and at least one second channel; the first channel and the second channel have a common end area; the first channel in the end area has a stopping mechanism for stopping of a liquid flow flowing in the first channel; the stopping mechanism can be controlled by means of a liquid flow flowing in the second channel for continuing the liquid flow in the first channel. Transport in the first and the second channel takes place advantageously by the capillarity acting in the channel.Type: GrantFiled: January 23, 2004Date of Patent: November 14, 2006Assignee: Boehringer Ingelheim Microparts GmbHInventors: Ralf Peters, Gert Blankenstein, Holger Bartos, Claus Marquordt
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Publication number: 20060216195Abstract: A device and a process for testing a sample liquid wherein the sample liquid flows laminarly by capillary forces over a flat side of a channel to completely filling a reaction area which has a soluble and/or reacting reagent on the flat side and defines a reaction volume of the sample liquid, the reaction volume being temporarily stopped in the reaction area for dissolving or reacting at least 90% of the reagent in the defined reaction volume of the sample liquid, and at least 90% of the dissolved reagent or a reaction product, after stopping, flows together with the reaction volume into the test area which is formed by the channel downstream of the reaction area, the sample liquid flowing with an at least essentially straight liquid front and/or at least essentially without a change in the flow cross section from the reaction area into the test area.Type: ApplicationFiled: January 27, 2006Publication date: September 28, 2006Applicant: Boehringer Ingelheim microParts GmbHInventors: Gert Blankenstein, Ralf-Peter Peters, Thomas Willms, Claus Marquordt, Christian Schoen
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Publication number: 20050249641Abstract: A microstructured platform for manipulating a wetting liquid including at least one cavity and a channel system for transporting the liquid. At least some of the channels of the channel system are made as capillaries which have a dimension in the millimeter range or less in at least one direction transverse to the transport direction of the liquid. The platform also includes at least one other microstuctured element disposed in the transport path of the liquid. The microstructured element may be in the form of a fluidic switch, metering means, separating device, or a region for holding together a limited amount of liquid. The structure facilitates or enables the manipulation of liquids when only a small amount of liquid is available and extensive analyses are to be performed with the liquid.Type: ApplicationFiled: April 8, 2005Publication date: November 10, 2005Applicant: Boehringer Ingelheim microParts GmbHInventors: Gert Blankenstein, Thomas Willms, Ralf-Peter Peters, Claus Marquordt, Holger Bartos
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Publication number: 20050169778Abstract: The present invention relates to a microstructure arrangement for the bubble-free filling with a liquid of at least one system for draining off liquids. The arrangement has an inlet for the arrangement to be connected to a system for the supply of liquids and at least one outlet for the arrangement to be connected to the at least one liquid-discharging system. The arrangement has a transition region, through which the liquid can be transported from the inlet to the at least one outlet. At a start of the transition region, at least one first microstructure element for producing a point with increased capillary force is provided, in order to achieve gap-free wetting of the areas bounding this point with increased capillary force, in particular side walls, a cover and/or a bottom.Type: ApplicationFiled: December 20, 2004Publication date: August 4, 2005Inventors: Gert Blankenstein, Ralf-Peter Peters, Claus Marquordt
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Publication number: 20050106756Abstract: A microstructured separation device for separating parts of a liquid which comprises liquid components and at least one type of particle and/or at least one complex of interconnected particles of at least one type, with the following features: the device has an inlet for the liquid, a collection section, and a transport path from the inlet to the collection section; the transport path includes, situated one after the other in the direction of transport, a resuspension section, an incubation section, a first separation section for holding back at least some of the complexes and/or for slowing down the movement of at least some of the complexes and/or at least some of the particles, and a second separation section for holding back at least some of the complexes and/or at least some of the particles and/or for slowing down the movement of the particles; and the first separation section and second separation section have a microstructure with one or more microstructure elements.Type: ApplicationFiled: November 8, 2004Publication date: May 19, 2005Inventors: Gert Blankenstein, Claus Marquordt
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Publication number: 20040206408Abstract: The invention relates to a microfluidic switch for stopping a liquid flow during a time interval with the following features: the switch has at least one first channel and at least one second channel; the first channel and the second channel have a common end area; the first channel in the end area has a stopping mechanism for stopping of a liquid flow flowing in the first channel; the stopping mechanism can be controlled by means of a liquid flow flowing in the second channel for continuing the liquid flow in the first channel. Transport in the first and the second channel takes place advantageously by the capillarity acting in the channel.Type: ApplicationFiled: January 23, 2004Publication date: October 21, 2004Inventors: Ralf-Peter Peters, Gert Blankenstein, Holger Bartos, Claus Marquordt
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Patent number: D617468Type: GrantFiled: May 27, 2009Date of Patent: June 8, 2010Assignees: Inverness Medical Innovations, Inc., Boehringer Ingelheim microParts GmbHInventors: Claus Marquordt, Murray Whyte, Christian Schoen, Thanh Tu Duong
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Patent number: D621059Type: GrantFiled: October 2, 2007Date of Patent: August 3, 2010Assignee: Alere Switzerland GmbHInventors: Claus Marquordt, David William Taylor, Colin Hanna, David Kinniburgh Lang, Brian McGuigan, Colin Boyd, Jonathan Chua Cheng Lam, Allen Lai Siew Kong, Chun Keat Ooi