Abstract: The present document relates to audio coding systems. In particular, the present document relates to efficient methods and systems for parametric multi-channel audio coding. An audio encoding system configured to generate a bitstream indicative of a downmix signal and spatial metadata for generating a multi-channel upmix signal from the downmix signal is described. The system comprises a downmix processing unit configured to generate the downmix signal from a multi-channel input signal; wherein the downmix signal comprises m channels and wherein the multi-channel input signal comprises n channels; n, m being integers with m<n. Furthermore, the system comprises a parameter processing unit configured to determine the spatial metadata from the multi-channel input signal.

Abstract: A method for amplification of nucleic acids in which substantially use is made of the fact that a pre-defined nucleic acid chain (target sequence) can be multiplied/amplified in the presence of a target sequence-specific activator oligonucleotide. The target sequence-specific activator oligonucleotide causes the separation of re-synthesized complementary primer extension products by strand displacement, so that a new primer oligonucleotide can attach to the respective template strand. The thus formed complex of a primer oligonucleotide and a template strand can initiate a new primer extension reaction. The thus formed primer extension products in turn function as templates, so that an exponential amplification reaction results.

Abstract: A façade structure is described, preferably a curtain-wall back-ventilated façade structure, with a substructure formed from support profiles which is arranged in front of a building wall and anchored fixedly in the floor and/or in the building wall, with extruded façade tiles made of ceramic material, preferably clay material, which are fastened to the substructure via tile holders. In order to be able to arrange the façade tiles in the vertical format, in addition to the tile holders which grip on the vertical edges of the façade tiles, it is provided that weight-supporting holders, which have receivers which engage in each case in a lower edge of the façade tiles, are fastened to the support profiles to which the tile holders are fastened or to further support profiles of the substructure directly or via separate supports.

Abstract: A façade structure is described, with a substructure formed of support profiles, which is arranged in front of a building wall and anchored fixedly in the floor and/or in the building wall, with extruded façade tiles made of ceramic material, which are fastened to the substructure via tile holders, wherein the tile holders are arranged on all or only some of the support profiles, the tile holders being fastened to the support profiles directly or via separate supports, and the tile holders having receivers, which engage with edge areas of the façade tiles to fasten the façade tiles.

Abstract: A braking system for a rail vehicle includes a target value generator for the target value of the overall braking power, a controller for determining at least one manipulated variable value on the basis of the target value and at least one actuator which transmits the manipulated variable value to the at least one braking device. The system at least approximately determines acceleration components of the rail vehicle and determines the actual value of the total braking power from the acceleration components while taking the vehicle speed and the vehicle mass into consideration. The controller is designed to control the manipulated variable value such as to reduce the control deviation between the target value and the determined actual value.

Abstract: The present invention provides a tomaymycin biosynthetic gene cluster of Streptomyces species FH6421, and its use for producing 11-de-O-methyltomaymycin.

Abstract: The present document relates to audio coding systems. In particular, the present document relates to efficient methods and systems for parametric multi-channel audio coding. An audio encoding system configured to generate a bitstream indicative of a downmix signal and spatial metadata for generating a multi-channel upmix signal from the downmix signal is described. The system comprises a downmix processing unit configured to generate the downmix signal from a multi-channel input signal; wherein the downmix signal comprises m channels and wherein the multi-channel input signal comprises n channels; n, m being integers with m<n. Furthermore, the system comprises a parameter processing unit configured to determine the spatial metadata from the multi-channel input signal.

Abstract: A hinge assembly comprises first and second tape spring elements, wherein each of the spring elements is configured to connect a first element of a space structure to a second element of the space structure. Each of the first and the second tape spring elements is movable from a folded state into an unfolded state by releasing stored strain energy, to deploy the first and the second element of the space structure. The first tape spring element is connected to a first direct current source and configured to conduct direct current of a first polarity supplied to the first tape spring element from the first direct current source. The second tape spring element is connected to a second direct current source and configured to conduct direct current of a second polarity, opposite to the first polarity, supplied to the second tape spring element from the second direct current source.

Abstract: An aircraft structural component having a skin element, including an inner surface, a multitude of transverse stiffening elements, which lie against the inner surface of the skin element, and a multitude of longitudinal stiffening elements, perpendicular to the transverse stiffening elements against the inner surface of the skin element, wherein between a first and a second transverse stiffening element and also between a first and a second longitudinal stiffening element, a first skin section is defined. An aircraft structural component is provided with the quantity of the longitudinal stiffening elements reduced. A first applied reinforcement includes a core layer having a contour line running along the circumference of the skin element, the first applied reinforcement including a face sheet surrounding the core layer on the side thereof which faces away from the skin element, which face sheet is connected to the skin element along the core layer contour line.

Abstract: The present document relates to audio coding systems. In particular, the present document relates to efficient methods and systems for parametric multi-channel audio coding. An audio encoding system configured to generate a bitstream indicative of a downmix signal and spatial metadata for generating a multi-channel upmix signal from the downmix signal is described. The system comprises a downmix processing unit configured to generate the downmix signal from a multi-channel input signal; wherein the downmix signal comprises m channels and wherein the multi-channel input signal comprises n channels; n, m being integers with m<n. Furthermore, the system comprises a parameter processing unit configured to determine the spatial metadata from the multi-channel input signal.

Abstract: It is disclosed a method for amplification of nucleic acids in which substantially use is made of the fact that a pre-defined nucleic acid chain (target sequence) can be multiplied/amplified in the presence of a target sequence-specific activator oligonucleotide. The target sequence-specific activator oligonucleotide causes the separation of re-synthesized complementary primer extension products by means of strand displacement, so that a new primer oligonucleotide can attach to the respective template strand. The thus formed complex of a primer oligonucleotide and a template strand can initiate a new primer extension reaction. The thus formed primer extension products in turn function as templates, so that an exponential amplification reaction results. Here, the activator oligonucleotide itself does not function as a template and preferably is inert over a primer extension reaction.

Abstract: A rail vehicle compressor system comprises a compressor, driven by an electrical machine via a drive shaft, for producing compressed air for at least one compressed air tank. The electrical machine is activated at least indirectly via a control device for operating the electrical machine at least one nominal speed between a maximum speed and a minimum speed. At least one pressure sensor determines the pressure for the control device and is disposed in a compressed-air-carrying line downstream of the compressor. A final control element for continuously influencing the speed of the electrical machine is disposed between an electrical supply and the electrical machine, wherein the control device controls activation of the final control element. A method for controlling the compressor system is also provided, wherein, the compressor is operated at a variable speed in between the maximum speed and the minimum speed based on rail vehicle operating state.

Abstract: A braking system for a rail vehicle includes a target value generator for the target value of the overall braking power, a controller for determining at least one manipulated variable value on the basis of the target value and at least one actuator which transmits the manipulated variable value to the at least one braking device. The system at least approximately determines acceleration components of the rail vehicle and determines the actual value of the total braking power from the acceleration components while taking the vehicle speed and the vehicle mass into consideration. The controller is designed to control the manipulated variable value such as to reduce the control deviation between the target value and the determined actual value.

Abstract: A bearing element (1) for a plain or antifriction bearing is provided, the bearing element (1) being formed of or including at least sectionally a powder-metallurgical composite material which includes a metallic binder phase and a hard material phase, wherein the metallic binder phase is based on at least one element from the following group: chromium, cobalt, molybdenum, nickel, titanium.

Abstract: A rail vehicle compressor system comprises a compressor, driven by an electrical machine via a drive shaft, for producing compressed air for at least one compressed air tank. The electrical machine is activated at least indirectly via a control device for operating the electrical machine at at least one nominal speed between a maximum speed and a minimum speed. At least one pressure sensor determines the pressure for the control device and is disposed in a compressed-air-carrying line downstream of the compressor. A final control element for continuously influencing the speed of the electrical machine is disposed between an electrical supply and the electrical machine, wherein the control device controls activation of the final control element. A method for controlling the compressor system is also provided, wherein, the compressor is operated at a variable speed in between the maximum speed and the minimum speed based on rail vehicle operating state.

Abstract: A bearing module including a first bearing component and a second bearing component which are mounted such that the first bearing component and the second bearing component can move relative to one another, the first bearing component being an outer ring extending in a circumferential direction and the second bearing copmonent being a corresponding inner ring, a raceway is provided on one of the outer bearing and the inner bearing ring, and corrosion protection is provided at a side of the raceway, the corrosion protection being anodic corrosion protection and including one of a sacrificial anode or an impressed current anode. A separate protection means is provided, which is comprised of an oligodynamically acting material.

Abstract: The invention relates to pyridine derivatives of Formula (I) wherein A, R1, R2, R3, and R4 are as described in the description, their preparation and their use as pharmaceutically active compounds. Said compounds particularly act as immunomodulating agents.

Abstract: The invention relates to pharmaceutical compositions containing at least one thiazolidin-4-one derivative to prevent or treat disorders associated with an activated immune system. Furthermore, the invention relates to novel thiazolidin-4-one derivatives notably for use as pharmaceutically active compounds. Said compounds particularly act also as immunosuppressive agents.

Abstract: The invention relates to pharmaceutical compositions containing at least one thiazolidin-4-one derivative to prevent or treat disorders associated with an activated immune system. Furthermore, the invention relates to novel thiazolidin-4-one derivatives notably for use as pharmaceutically active compounds. Said compounds particularly act also as immunosuppressive agents.

Abstract: Process for removing mercury from flue gases of high-temperature plants, in particular power stations and waste incineration plants in which a bromine compound is fed to the multistage furnace and/or the flue gas in a plant section downstream of the furnace, the temperature during contact of the bromine compound with the flue gas being at least 500° C., preferably at least 800° C. The combustion is carried out in the presence of a sulphur compound, in particular sulphur dioxide. Subsequently to the furnace, the flue gas is subjected to an optional multistage cleanup for removing mercury from the flue gas, which cleanup comprises a wet scrubber and/or a dry cleanup.