Abstract: Medical devices and methods for making and using the same. An example medical device may include an elongate core member having a proximal portion and a distal portion. The distal portion may include a distal end and a flattened region. The flattened region may be disposed proximally of the distal end. The flattened region may have a height and a width. The width may be twice or more as large as the height. A tubular member may be disposed over the distal portion. The tubular member may have a plurality of slots formed therein.

Abstract: Medical devices for navigation through anatomy, including guidewires, which may have a core wire, a slotted tubular member, or both. Embodiments may have coils, including non-circular cross-section edge-wound marker coils, extended coil tips, and soldered or glued mesial joint coils. Core wires may have a step, ridge, or taper at the joints to the tubular member, and may be flattened at the distal tip. Radiopaque material may be located inside the tubular member, and the distal tip may be heat treated to make it shapeable. Additional tubular members or coils may be used concentrically or in line and may enhance flexibility, provide radiopacity, reduce friction, or reduce material or manufacturing cost. Tubular members may be chamfered or tapered continuously or incrementally. Slots may be arranged in groups, such as groups of three, and may be equal in depth or unequal in depth to provide a steerable or compressible tip.

Abstract: A coil for use in a medical device. The coil includes a plurality of coil windings or turns, wherein adjacent coil windings are connected together at a plurality of discrete connection locations to increase the torsional rigidity and torque transmitting properties of the coil without sacrificing the flexibility characteristics of the coil. In some embodiments the coil may be a wave wound coil, such as a nested wave wound coil or a crest-to-crest wave wound coil.

Abstract: An elongate medical device such as a guidewire, that may comprise a first elongate member having a proximal end, a distal end and a lumen there between, a second elongate member having a proximal end and a distal end, the second elongate member at least partially disposed in the first elongate member, a first connection between first elongate member and the second elongate member at the proximal end of the first elongate member, a second connection between the first elongate member and the second elongate member at the distal end of the first elongate member, and a third connection between the first elongate member and the second elongate member, the third connection disposed at a point between the first connection and the second connection, wherein the third connection is substantially at a location selected by the Method for Enhancing the Ratio of Torsional Stiffness to Transverse Flexibility.

Abstract: Medical devices for navigation through anatomy, including guidewires, which may have a core wire, a slotted tubular member, or both. Embodiments may have coils, including non-circular cross-section edge-wound marker coils, extended coil tips, and soldered or glued mesial joint coils. Core wires may have a step, ridge, or taper at the joints to the tubular member, and may be flattened at the distal tip. Radiopaque material may be located inside the tubular member, and the distal tip may be heat treated to make it shapeable. Additional tubular members or coils may be used concentrically or in line and may enhance flexibility, provide radiopacity, reduce friction, or reduce material or manufacturing cost. Tubular members may be chamfered or tapered continuously or incrementally. Slots may be arranged in groups, such as groups of three, and may be equal in depth or unequal in depth to provide a steerable or compressible tip.

Abstract: An elongated medical device and components therefore, and methods for making and using the same. An example embodiment includes an elongated metallic tubular member including a tapered transition region disposed between two sections having different physical characteristics, such as flexibility characteristics. In some cases, the tubular member includes a section including a plurality of slots formed therein. Some example embodiments include a medical device including such a tubular member.

Abstract: Medical devices for navigation through anatomy, including guidewires, which may have a core wire, a slotted tubular member, or both. Embodiments may have coils, including non-circular cross-section edge-wound marker coils, extended coil tips, and soldered or glued mesial joint coils. Core wires may have a step, ridge, or taper at the joints to the tubular member, and may be flattened at the distal tip. Radiopaque material may be located inside the tubular member, and the distal tip may be heat treated to make it shapeable. Additional tubular members or coils may be used concentrically or in line and may end in depth radunequal in depth opacity, reduce friction, or reduce material or manufacturing cod in groups, such as groups of three, and may be equally spaced around the axis or offset to provide a steerable or compressible tip.

Abstract: Medical devices and methods for making and using the same. A medical device may include an elongate tubular member. The tubular member may include a first circumferential tube segment, a second circumferential tube segment disposed next to the first circumferential tube segment, and a third circumferential tube segment disposed next to the second circumferential tube segment. The first tube segment and the second tube segment may be separated by a first set of slots formed in the tubular member. The second tube segment and the third tube segment may be separated by a second set of slots formed in the tubular member. The second tube segment may be connected to the first tube segment with a proximally-extending beam formed in the tubular member. The second tube segment may also be connected to the third tube segment with a distally-extending beam formed in the tubular member. A ring may be defined in the second tube segment between the proximally-extending beam and the distally-extending beam.

Abstract: Medical devices and methods for making and using the same. An example medical device may include an elongate core member having a proximal portion and a distal portion. The distal portion may include a distal end and a flattened region. The flattened region may be disposed proximally of the distal end. The flattened region may have a height and a width. The width may be twice or more as large as the height. A tubular member may be disposed over the distal portion. The tubular member may have a plurality of slots formed therein.

Abstract: Medical devices and methods for making and using the same. An example medical devices includes a core member and a tubular member disposed over a portion of the core member. The tubular member has a plurality of slots formed therein.

Abstract: A coil for use in a medical device. The coil includes a plurality of coil windings or turns, wherein adjacent coil windings are connected together at a plurality of discrete connection locations to increase the torsional rigidity and torque transmitting properties of the coil without sacrificing the flexibility characteristics of the coil. In some embodiments the coil may be a wave wound coil, such as a nested wave wound coil or a crest-to-crest wave wound coil.

Abstract: A laser shock peening process for producing one or more compressive residual stress regions in a medical device is disclosed. A high-energy laser apparatus can be utilized to direct an intense laser beam through a confining medium and onto the target surface of a workpiece. An absorption overlay disposed on the target surface of the workpiece absorbs the laser beam, inducing a pressure shock wave that forms a compressive residual stress region deep within the workpiece. Medical devices such as stents, guidewires, catheters, and the like having one or more of these compressive residual stress regions are also disclosed.

Abstract: Medical devices and methods for making and using the same. An example medical device may include an elongate core member and a tubular member disposed about a portion of the core member. The tubular member may have a plurality of slots formed therein. The medical devices may be configured to have a preferential bending direction.

Abstract: An elongate medical device such as a guidewire, that may comprise a first elongate member having a proximal end, a distal end and a lumen there between, a second elongate member having a proximal end and a distal end, the second elongate member at least partially disposed in the first elongate member, a first connection between first elongate member and the second elongate member at the proximal end of the first elongate member, a second connection between the first elongate member and the second elongate member at the distal end of the first elongate member, and a third connection between the first elongate member and the second elongate member, the third connection disposed at a point between the first connection and the second connection, wherein the third connection is substantially at a location selected by the Method for Enhancing the Ratio of Torsional Stiffness to Transverse Flexibility.

Abstract: Medical devices and methods for making and using the same. An example medical device may include an elongate shaft having a proximal region and a distal region. A tubular member may be disposed over the distal region of the shaft. The tubular member may have an outer surface and may have a plurality of slots formed therein. A coil may be disposed adjacent the tubular member.

Abstract: Medical devices for navigation through anatomy, including guidewires, which may have a core wire, a slotted tubular member, or both. Embodiments may have coils, including non-circular cross-section edge-wound marker coils, extended coil tips, and soldered or glued mesial joint coils. Core wires may have a step, ridge, or taper at the joints to the tubular member, and may be flattened at the distal tip. Radiopaque material may be located inside the tubular member, and the distal tip may be heat treated to make it shapeable. Additional tubular members or coils may be used concentrically or in line and may enhance flexibility, provide radiopacity, reduce friction, or reduce material or manufacturing cost. Tubular members may be chamfered or tapered continuously or incrementally. Slots may be arranged in groups, such as groups of three, and may be equal in depth or unequal in depth to provide a steerable or compressible tip.

Abstract: Medical devices for navigation through anatomy, including guidewires, which may have a core wire, a slotted tubular member, or both. Embodiments may have coils, including non-circular cross-section edge-wound marker coils, extended coil tips, and soldered or glued mesial joint coils. Core wires may have a step, ridge, or taper at the joints to the tubular member, and may be flattened at the distal tip. Radiopaque material may be located inside the tubular member, and the distal tip may be heat treated to make it shapeable. Additional tubular members or coils may be used concentrically or in line and may enh in depth radunequal in depth opacity, reduce friction, or reduce material or manufacturing cod in groups, such as groups of three, and may be equally spaced around the axis or offset to provide a steerable or compressible tip.

Abstract: Sealing assemblies are illustrated for heaters, pumps, conduits, and the like for handling process fluids used in the semiconductor-processing industry. Clean, particle-free, nonreactive, non-trapping, ultra-pure, thermally tolerant, sealed systems are required to maintain process fluids with contaminant levels below parts per billion, or even trillion. A lip seal connects a tube, having a lip at each end, to a face of a creeping material. A creeping fluorocarbon sealing material may form the interface for reducing stress concentrations on the tube, and for providing a consistent reliable seal between the lip and the creeping face. A face seal between creeping faces may be effected by a creeping sealant there between. The faces may be loaded entirely by their own creeping structural materials. No flanges are required. In certain embodiments, retaining rings may be provided for preventing unrestrained creep of sealing assemblies.