Abstract: The present inventors identified a subpopulation of genes induced by type I and type II IFNs in a human submandibular gland (HSG) epithelial cell line. Unexpectedly, it was found that the majority of genes that are highly up-regulated by IFN-? are also highly induced by IFN-?. In contrast, there was a substantial group of genes that are highly induced by IFN-? only. In target tissues, this identified subpopulation of genes and probes allow different IFN patterns to be discerned, enabling more precise molecular classification of patient subpopulations. The identified gene probes are useful for selecting and monitoring therapy, and for defining efficacy of novel agents in the autoimmune rheumatic diseases.

Abstract: The present inventors identified a subpopulation of genes induced by type I and type II IFNs in a human submandibular gland (HSG) epithelial cell line. Unexpectedly, it was found that the majority of genes that are highly up-regulated by IFN-? are also highly induced by IFN-?. In contrast, there was a substantial group of genes that are highly induced by IFN-? only. In target tissues, this identified subpopulation of genes and probes allow different IFN patterns to be discerned, enabling more precise molecular classification of patient subpopulations. The identified gene probes are useful for selecting and monitoring therapy, and for defining efficacy of novel agents in the autoimmune rheumatic diseases.

Abstract: Provided herein is technology relating to polymer nanocomposites, and particularly, but not exclusively, to polymer nanocomposites comprising two or more nanomaterials and methods of producing nanocomposites comprising two or more nanomaterials.

Abstract: The present inventors identified a subpopulation of genes induced by type I and type II IFNs in a human submandibular gland (HSG) epithelial cell line. Unexpectedly, it was found that the majority of genes that are highly up-regulated by IFN-? are also highly induced by IFN-?. In contrast, there was a substantial group of genes that are highly induced by IFN-? only. In target tissues, this identified subpopulation of genes and probes allow different IFN patterns to be discerned, enabling more precise molecular classification of patient subpopulations. The identified gene probes are useful for selecting and monitoring therapy, and for defining efficacy of novel agents in the autoimmune rheumatic diseases.

Abstract: Provided herein is technology relating to polymer-graphene nanocomposites and particularly, but not exclusively, to methods for producing polymer-graphene nanocomposites using master batches comprising graphene and a polymer or polymer precursor. The resulting polymer-graphene nanocomposites comprise a high degree of exfoliation and dispersion of graphene nanoplatelets within the polymer matrix.

Abstract: Provided herein is technology relating to polymer nanocomposites, and particularly, but not exclusively, to polymer nanocomposites comprising two or more nanomaterials and methods of producing nanocomposites comprising two or more nanomaterials.

Abstract: Provided herein is technology relating to polymer-graphene nanocomposites and particularly, but not exclusively, to methods for producing polymer-graphene nanocomposites using master batches comprising graphene and a polymer or polymer precursor. The resulting polymer-graphene nanocomposites comprise a high degree of exfoliation and dispersion of graphene nanoplatelets within the polymer matrix.

Abstract: The present inventors identified a subpopulation of genes induced by type I and type II IFNs in a human submandibular gland (HSG) epithelial cell line. Unexpectedly, it was found that the majority of genes that are highly up-regulated by IFN-? are also highly induced by IFN-?. In contrast, there was a substantial group of genes that are highly induced by IFN-? only. In target tissues, this identified subpopulation of genes and probes allow different IFN patterns to be discerned, enabling more precise molecular classification of patient subpopulations. The identified gene probes are useful for selecting and monitoring therapy, and for defining efficacy of novel agents in the autoimmune rheumatic diseases.

Abstract: A computer system for facilitating payments from an account according to particular embodiments of the invention is adapted for: (1) facilitating the transmission, to a plan service provider, of a first set of documentation of a first payment that would potentially qualify for reimbursement from the account; (2) receiving, from the plan service provider, verification that the first payment has been verified as qualifying for reimbursement from the account according to a set of reimbursement rules associated with the account; (3) storing, in memory, an electronic version of the first set of documentation; and (4) storing, in memory, an indication that the first payment has been verified as being properly reimbursable from the account.

Abstract: A computer system for facilitating payments from an account according to particular embodiments of the invention is adapted for: (1) facilitating the transmission, to a plan service provider, of a first set of documentation of a first payment that would potentially qualify for reimbursement from the account; (2) receiving, from the plan service provider, verification that the first payment has been verified as qualifying for reimbursement from the account according to a set of reimbursement rules associated with the account; (3) storing, in memory, an electronic version of the first set of documentation; and (4) storing, in memory, an indication that the first payment has been verified as being properly reimbursable from the account.

Abstract: A computer system for facilitating payments from an account according to particular embodiments of the invention is adapted for: (1) facilitating the transmission, to a plan service provider, of a first set of documentation of a first payment that would potentially qualify for reimbursement from the account; (2) receiving, from the plan service provider, verification that the first payment has been verified as qualifying for reimbursement from the account according to a set of reimbursement rules associated with the account; (3) storing, in memory, an electronic version of the first set of documentation; and (4) storing, in memory, an indication that the first payment has been verified as being properly reimbursable from the account.

Abstract: A computer system for facilitating payments from an account according to particular embodiments of the invention is adapted for: (1) facilitating the transmission, to a plan service provider, of a first set of documentation of a first payment that would potentially qualify for reimbursement from the account; (2) receiving, from the plan service provider, verification that the first payment has been verified as qualifying for reimbursement from the account according to a set of reimbursement rules associated with the account; (3) storing, in memory, an electronic version of the first set of documentation; and (4) storing, in memory, an indication that the first payment has been verified as being properly reimbursable from the account.

Abstract: A computer system for facilitating payments from an account according to particular embodiments of the invention is adapted for: (1) facilitating the transmission, to a plan service provider, of a first set of documentation of a first payment that would potentially qualify for reimbursement from the account; (2) receiving, from the plan service provider, verification that the first payment has been verified as qualifying for reimbursement from the account according to a set of reimbursement rules associated with the account; (3) storing, in memory, an electronic version of the first set of documentation; and (4) storing, in memory, an indication that the first payment has been verified as being properly reimbursable from the account.

Abstract: A computer system according to particular embodiments of the invention is adapted for: (A) receiving one or more claims for reimbursement from an account holder of a health savings account; (B) after receiving the one or more claims, allowing a plan service provider to: (1) review each particular one of the one or more claims for reimbursement to determine whether the particular claim is properly reimbursable from the health savings account; and (2) in response to determining that the particular claim is reimbursable from the health savings account, certify that the particular claim is properly reimbursable from the health savings account.