Patents by Inventor Clayton Rische

Clayton Rische has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20180042848
    Abstract: Immunoregulatory spherical nucleic acids (irSNAs) composed of a lipid containing core and an inert Nucleic non-TLR antagonistic oligonucleotide shell are provided. Acid Shell These it-SNAs are useful for modulating an immune response.
    Type: Application
    Filed: February 18, 2016
    Publication date: February 15, 2018
    Applicant: Exicure, Inc.
    Inventors: Sergei Gryaznov, Aleksandar Filip Radovic-Moreno, Christopher C. Mader, Tiffany L. Halo, Richard Kang, Subbarao Nallagatla, Clayton Rische, Sagar Anantatatmula
  • Publication number: 20160194642
    Abstract: Aspects of the invention relate to nanoscale constructs and related methods and compositions thereof. The compositions of the invention are useful for treating disorders that are sensitive to levels of immune cell activation, such as autoimmune disease or other inflammation based disease or disorder.
    Type: Application
    Filed: July 25, 2014
    Publication date: July 7, 2016
    Applicant: Exicure, Inc
    Inventors: Sergei Gryaznov, Christopher C. Mader, Tiffany L. Halo, Aleksandar Filip Radovic-Moreno, Clayton Rische, Sagar Anantatmula