Abstract: Lateral flow devices, methods and kits for performing lateral flow assays are provided.

Abstract: Lateral flow devices, methods and kits for performing lateral flow assays are provided.

Abstract: Lateral flow devices, methods and kits for performing lateral flow assays are provided.

Abstract: Lateral flow devices, methods and kits for performing lateral flow assays are provided.

Abstract: Lateral flow devices, methods and kits for performing lateral flow assays are provided.

Abstract: Systems and methods for producing blot images. A blot, for example a western blot, is imaged using an imaging system having a field of view and a magnification. Features of interest in the blot correspond to features in the digital image, and the sizes of the features in the digital image depend on the magnification of the imaging system. A structuring element is selected based on the sizes and shapes of the features in the digital image, and the image is morphologically eroded and dilated varying numbers of times. The eroded and dilated image is subtracted from the original blot image to remove background signal from the blot image, producing an output image. The number of erosions needed to completely erode the features of interest is determined automatically, for example by investigating the behavior of the kurtosis of the output image as a function of the number of erosions performed.

Abstract: Lateral flow devices, methods and kits for performing lateral flow assays are provided.

Abstract: Lateral flow devices, methods and kits for performing lateral flow assays are provided.

Abstract: Methods and compositions for imaging and scanning Western or immunoblots are disclosed herewith.

Abstract: A lateral flow apparatus is provided.

Abstract: Lateral flow devices, methods and kits for performing lateral flow assays are provided.

Abstract: Molding systems and methods of using such systems are provided.

Abstract: Compositions, methods, articles of manufacture, and kits are provided for storage and delivery of proteins.

Abstract: Lateral flow devices, methods and kits for performing lateral flow assays are provided.

Abstract: Systems and methods for producing blot images. A blot, for example a western blot, is imaged using an imaging system having a field of view and a magnification. Features of interest in the blot correspond to features in the digital image, and the sizes of the features in the digital image depend on the magnification of the imaging system. A structuring element is selected based on the sizes and shapes of the features in the digital image, and the image is morphologically eroded and dilated varying numbers of times. The eroded and dilated image is subtracted from the original blot image to remove background signal from the blot image, producing an output image. The number of erosions needed to completely erode the features of interest is determined automatically, for example by investigating the behavior of the kurtosis of the output image as a function of the number of erosions performed.

Abstract: Lateral flow devices, methods and kits for performing lateral flow assays are provided.

Abstract: Kits, systems, and methods are provided for transferring biological macromolecules from an electrophoresis slab gel to a blotting membrane using conductive polymer electrodes.

Abstract: Devices, systems, methods, and kits are provided for performing separation, immobilization, blotting, and/or detection of analytes from biological samples. In some embodiments, the devices are constructed from two solid substrates with surfaces in contact. The devices include a plurality of channels formed from indentations in these surfaces. The indentations can be aligned with each other across the interface between the substrates, and realigned by shifting or sliding one substrate relative to the other. In some embodiments, the devices are constructed from three layers of a solid substrate. A separation channel in the middle layer of the device is first used for analyte separation. The middle layer can then be slid relative the top and/or bottom layer, thereby aligning the separation channel with a blotting membrane. Analytes can then be transferred to the membrane using electrodes in the top and bottom layers.

Abstract: Compositions, methods, articles of manufacture, and kits are provided for storage and delivery of proteins.

Abstract: Molecular species that are immobilized in discrete locations on a planar support such as protein bands on a gel or a blotting membrane or species applied in dots or spots on a membrane are reacted with binding reagents that are applied through a porous hydrophilic transfer sheet placed over the planar support, the sheet having at least one region that is laterally bordered by a barrier with the binding reagent retained within the bordered region. The bordered region is placed directly over an area on the planar support where the molecular species are expected to reside if they are present on the support. The binding reagent is then delivered into the support to contact the species. Targeted delivery of the binding reagent is thus achieved with improved efficiency.