Abstract: A microfluidic diagnostic device (1, 50) comprising a substrate (4); a compatible layer (6) formed on a first face (4a) of the substrate (4); a structural layer (8), formed on top of the compatible layer (6); a channel (10), formed in the structural layer (8) and limited underneath by the compatible layer (6), optically accessible by a first luminous radiation having a first wavelength (?e); and a cover layer (18) made of a material transparent to the first wavelength (?e), arranged on top of the structural layer (8) and sealing the channel (10) at the top, wherein the compatible layer (6) has a thickness equal to approximately a quarter of the first wavelength (?e) divided by the refraction index of the compatible layer (6), or equal to an odd multiple of a quarter of the first wavelength (?e) divided by the refraction index of the compatible layer (6).

Abstract: A confocal optical detector including a light source generating a first optical beam along an axis; an optoelectronic sensor; an optical focusing device, which receives and focuses the first optical beam; and a hole, which receives the first optical beam and is arranged between the optoelectronic sensor and the optical focusing device. The optoelectronic sensor is arranged between the light source and the hole. In addition, the optoelectronic sensor and the optical focusing device are aligned along the axis.

Abstract: A confocal optical detector including a light source generating a first optical beam along an axis; an optoelectronic sensor; an optical focusing device, which receives and focuses the first optical beam; and a hole, which receives the first optical beam and is arranged between the optoelectronic sensor and the optical focusing device. The optoelectronic sensor is arranged between the light source and the hole. In addition, the optoelectronic sensor and the optical focusing device are aligned along the axis.

Abstract: PCR device (1) comprising at least a chamber (2), the chamber (2) being delimited on one side by a PCR substrate (3) at least partially covered by a polyelectrolyte coating (4) forming hydrophilic regions. The polyelectrolyte coating comprises at least one layer facing the chamber (2), the layer being a negatively charged polyelectrolyte layer. Further a hydrophobic polymer layer may be applied onto the PCR substrate facing the chamber forming hydrophobic regions delimiting the hydrophilic regions. Further a method for passivating a PCR substrate comprising the step of applying a polyelectrolyte is provided for.

Abstract: An integrated electromagnetic actuator comprising: a first structural layer; a flexible membrane, extending over the first structural layer and comprising regions of ferromagnetic material; a chamber, delimited between the first structural layer and the flexible membrane; a winding, comprising a plurality of turns of conductive material and extending within the first structural layer; and a core element made of ferromagnetic material, extending within the first structural layer, inside the winding.

Abstract: A microfluidic diagnostic device (1, 50) comprising a substrate (4); a compatible layer (6) formed on a first face (4a) of the substrate (4); a structural layer (8), formed on top of the compatible layer (6); a channel (10), formed in the structural layer (8) and limited underneath by the compatible layer (6), optically accessible by a first luminous radiation having a first wavelength (?e); and a cover layer (18) made of a material transparent to the first wavelength (?e), arranged on top of the structural layer (8) and sealing the channel (10) at the top, wherein the compatible layer (6) has a thickness equal to approximately a quarter of the first wavelength (?e) divided by the refraction index of the compatible layer (6), or equal to an odd multiple of a quarter of the first wavelength (?e) divided by the refraction index of the compatible layer (6).