Patents by Inventor Clemens Braun

Clemens Braun has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Combination of HMG-CoA reductase inhibitors with phosphodiesterase 4 inhibitors for the treatment of inflammatory pulmonary diseases
    Patent number: 9713614
    Abstract: The invention relates to the combined use of a PDE4 inhibitor with a HMG-CoA reductase inhibitor for the prevention and curative treatment of an inflammatory pulmonary disease.
    Type: Grant
    Filed: May 22, 2015
    Date of Patent: July 25, 2017
    Assignee: ASTRAZENECA AB
    Inventors: Stefan-Lutz Wollin, Andrea Wohlsen, Clemens Braun, Degenhard Marx
  • Pyrazolone-derivatives and their use as PDE-4 inhibitors
    Patent number: 9340522
    Abstract: The compounds of Formula (I), are novel effective inhibitors of the type 4 phosphodiesterase.
    Type: Grant
    Filed: November 15, 2013
    Date of Patent: May 17, 2016
    Assignee: TAKEDA GMBH
    Inventors: Imre Schlemminger, Beate Schmidt, Dieter Flockerzi, Hermann Tenor, Christof Zitt, Armin Hatzelmann, Degenhard Marx, Clemens Braun, Raimund Kuelzer, Anke Heuser, Hans-Peter Kley, Geert Jan Sterk
  • COMBINATION OF HMG-COA REDUCTASE INHIBITORS WITH PHOSPHODIESTERASE 4 INHIBITORS FOR THE TREATMENT OF INFLAMMATORY PULMONARY DISEASES
    Publication number: 20150272949
    Abstract: The invention relates to the combined use of a PDE4 inhibitor with a HMG-CoA reductase inhibitor for the prevention and curative treatment of an inflammatory pulmonary disease.
    Type: Application
    Filed: May 22, 2015
    Publication date: October 1, 2015
    Inventors: Stefan-Lutz WOLLIN, Andrea WOHLSEN, Clemens BRAUN, Degenhard MARX
  • 3,4,4a,10b-Tetrahydro-1H-thiopyrano-[44,3-c] isoquinoline derivatives
    Patent number: 9018175
    Abstract: The compounds of Formula (1), in which A, R1, R2, R3 and R5 have the meanings as given in the description, are novel effective inhibitors of type 4 and 5 phosphodiesterase.
    Type: Grant
    Filed: December 15, 2010
    Date of Patent: April 28, 2015
    Assignee: Takeda GmbH
    Inventors: Dieter Flockerzi, Thomas Stengel, Alexander Mann, Harald Ohmer, Ulrich Kautz, Steffen Weinbrenner, Stefan Fischer, Christof Zitt, Armin Hatzelmann, Torsten Dunkern, Christian Hesslinger, Thomas Maier, Hermann Tenor, Clemens Braun, Raimund Külzer, Degenhard Marx
  • NOVEL 3,4,4A,10B-TETRAHYDRO-1H-THIOPYRANO[4,3-C] ISOQUINOLINE COMPOUNDS
    Publication number: 20140113877
    Abstract: The compounds of formula (1) in which A, X, R1, R2, R3 and R7 have the meanings as given in the description, are novel effective inhibitors of type 4 and type 5 phosphodiesterase.
    Type: Application
    Filed: June 12, 2012
    Publication date: April 24, 2014
    Applicant: Takeda GmbH
    Inventors: Dieter Flockerzi, Alexander Mann, Thomas Stengel, Harald Ohmer, Ulrich Kautz, Steffen Weinbrenner, Stefan Fischer, Hermann Tenor, Christof Zitt, Armin Hatzelmann, Torsten Dunkern, Christian Hesslinger, Clemens Braun, Ewald Benediktus, Andreas Pahl, Raimund Kuelzer, Degenhard Marx
  • NOVEL PYRAZOLONE-DERIVATIVES AND THEIR USE AS PDE-4 INHIBITORS
    Publication number: 20140073672
    Abstract: The compounds of Formula (I), are novel effective inhibitors of the type 4 phosphodiesterase.
    Type: Application
    Filed: November 15, 2013
    Publication date: March 13, 2014
    Applicant: TAKEDA GMBH
    Inventors: Imre SCHLEMMINGER, Beate SCHMIDT, Dieter FLOCKERZI, Hermann TENOR, Christof ZITT, Armin HATZELMANN, Degenhard MARX, Clemens BRAUN, Raimund KUELZER, Anke HEUSER, Hans-Peter KLEY, Geert Jan STERK
  • Pyrazolone-derivatives and their use as PDE-4 inhibitors
    Patent number: 8609848
    Abstract: The compounds of Formula (I), are novel effective inhibitors of the type 4 phosphodiesterase.
    Type: Grant
    Filed: November 12, 2009
    Date of Patent: December 17, 2013
    Assignee: Takeda GmbH
    Inventors: Imre Schlemminger, Beate Schmidt, Dieter Flockerzi, Hermann Tenor, Christof Zitt, Armin Hatzelmann, Degenhard Marx, Clemens Braun, Raimund Külzer, Anke Heuser, Hans-Peter Kley, Geert Jan Sterk
  • 3,4,4A,10B-TETRAHYDRO-1H-THIOPYRANO-[4,3-c] ISOQUINOLINE DERIVATIVES
    Publication number: 20120289474
    Abstract: The compounds of Formula (1), in which A, R1, R2, R3 and R5 have the meanings as given in the description, are novel effective inhibitors of type 4 and 5 phosphodiesterase.
    Type: Application
    Filed: December 15, 2010
    Publication date: November 15, 2012
    Applicant: NYCOMED GMBH
    Inventors: Dieter Flockerzi, Thomas Stengel, Alexander Mann, Harald Ohmer, Ulrich Kautz, Steffen Weinbrenner, Stefan Fischer, Christof Zitt, Armin Hatzelmann, Torsten Dunkern, Christian Hesslinger, Thomas Maier, Hermann Tenor, Clemens Braun, Raimund Külzer, Degenhard Marx
  • NOVEL PYRAZOLONE-DERIVATIVES AND THEIR USE AS PDE-4 INHIBITORS
    Publication number: 20110218201
    Abstract: The compounds of Formula (I), are novel effective inhibitors of the type 4 phosphodiesterase.
    Type: Application
    Filed: November 12, 2009
    Publication date: September 8, 2011
    Applicant: NYCOMED GMBH
    Inventors: Imre Schlemminger, Beate Schmidt, Dieter Flockerzi, Hermann Tenor, Christof Zitt, Armin Hatzelmann, Degenhard Marx, Clemens Braun, Raimund Külzer, Anke Heuser, Hans-Peter Kley, Geert Jan Sterk
  • Combination of a Pd4 Inhibitor and a Tetrahydrobiopterin Derivative
    Publication number: 20080221111
    Abstract: The invention describes the use of a PDE4 inhibitor in combination with BH4 or a BH4 derivative for the prevention and/or treatment of respiratory diseases.
    Type: Application
    Filed: May 8, 2006
    Publication date: September 11, 2008
    Applicant: NYCOMED GmbH
    Inventors: Christian Hesslinger, Christian Schudt, Degenhard Marx, Clemens Braun
  • Brake lining wear indicating device
    Patent number: 5133431
    Abstract: A brake lining wear indicating device is inserted into an aperture (7) of a brake lining carrier (8) of a drum or disc brake from the side facing away from the brake lining (1) and secured in the aperture. The indicating device includes a slotted (16) sleeve shaped holder (2) and a contact member (3) inserted into and axially secured to the holder and has an electrical conductor (4) therein. In order that the indicating device can be fitted into brake lining carriers of different thickness, holder (2) has on its side facing away from the brake lining (1) a frustonconical section (13) having an outwardly narrowing inner frustoconical area (14) and several axially extending slots (16). When contact member (3) is inserted into holder (2), frustoconical part (13) of the holder is forcibly radially expanded and wedged into aperture (7) of brake lining carrier (8).
    Type: Grant
    Filed: March 1, 1991
    Date of Patent: July 28, 1992
    Assignee: Perrot-Bremse GmbH
    Inventor: Clemens Braun