Patents by Inventor Clemens Doppler

Clemens Doppler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of quantitatively detecting nucleic acids
    Patent number: 6136531
    Abstract: The invention describes a method of quantitatively detecting specific nucleotide sequences. Said method is essentially characterized in that a single-stranded nucleic acid, particularly mRNA, which has been isolated from a mixture, e.g. a biological sample, is hybridized in solution, with a polynucleotide sequence which is essentially complementary to the sequence to be determined; the nucleic acid is then immobilized on a solid phase, and the amount of bound hybrid is determined. It has proven to be particularly advantageous if the binding to the coated solid phase is accomplished with the aid of the specifically bindable chemical group which is coupled to the sequence to be determined or to the polynucleotide probe sequence via a linker.
    Type: Grant
    Filed: October 29, 1997
    Date of Patent: October 24, 2000
    Assignee: Roche Diagnostics GmbH
    Inventors: Hermann Leying, Matthias Hinzpeter, Hans-Peter Fritton, Clemens Doppler, Heiko Wittor
  • Method for the detection of metabolically labelled DNA
    Patent number: 5700639
    Abstract: The invention concerns a method for the non-radioactive detection of metabolically labelled DNA, in one aspect detecting labelled DNA indicative of cell lysis or apoptosis.
    Type: Grant
    Filed: June 9, 1994
    Date of Patent: December 23, 1997
    Assignee: Boehringer Mannheim GmbH
    Inventors: Bernhard Trauth, Matthias Hinzpeter, Clemens Doppler, Eberhard Russmann