Patents by Inventor Clement A. Stone

Clement A. Stone has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of treating hypertension
    Patent number: 4215110
    Abstract: A method of treating hypertension by administration, to hypertensive patients, of an anti-hypertensive amount of certain tripeptides, is disclosed.
    Type: Grant
    Filed: September 22, 1978
    Date of Patent: July 29, 1980
    Assignee: Merck & Co., Inc.
    Inventors: Victor J. Lotti, Clement A. Stone
  • Compositions and methods for treating glaucoma by the topical administration of t-butylamino-3-(4-morpholino-1,2,5-thiadiazol-3-yloxy-2-phopanol hydrogen maleate
    Patent number: 4195085
    Abstract: Antiglaucoma compositions containing t-butylamino-3-(4-morpholino-1,2,5-thiadiazol-3-yloxy)-2-propanol hydrogen maleate and method of treating elevated intraocular pressure.
    Type: Grant
    Filed: August 29, 1978
    Date of Patent: March 25, 1980
    Assignee: Merck & Co., Inc.
    Inventor: Clement A. Stone
  • Antihypertensive compositions containing N-heterocyclicalanines and .alpha. -
    Patent number: 4170654
    Abstract: Novel pharmaceutical compositions are disclosed. The compositions comprise an aryl substituted alanine and a substituted phenyl hydrazino propionic acid. The compositions are useful for treating hypertension.
    Type: Grant
    Filed: July 6, 1978
    Date of Patent: October 9, 1979
    Assignee: Merck & Co., Inc.
    Inventor: Clement A. Stone
  • Antihypertensive compositions containing an arylsubstituted alanine and a phenyl hydrazinopropionic acid
    Patent number: 4160835
    Abstract: Novel pharmaceutical compositions are disclosed. The compositions comprise an aryl substituted alanine and a substituted phenyl hydrazino propionic acid. The compositions are useful for treating hypertension.
    Type: Grant
    Filed: November 11, 1977
    Date of Patent: July 10, 1979
    Assignee: Merck & Co., Inc.
    Inventor: Clement A. Stone
  • Antihypertensive compositions containing an aryl-substituted alanine azo and an arylhydrazino-propionic acid
    Patent number: 4156734
    Abstract: Novel pharmaceutical compositions are disclosed. The compositions comprise an aryl substituted alanine and a substituted phenyl hydrazino propionic acid. The compositions are useful for treating hypertension.
    Type: Grant
    Filed: February 13, 1978
    Date of Patent: May 29, 1979
    Assignee: Merck & Co., Inc.
    Inventor: Clement A. Stone
  • Anti-hypertensive compositions
    Patent number: 4069333
    Abstract: Novel pharmaceutical compositions comprising hydrazino-phenylpropionic acid decarboxylase inhibitors and certain benzimidazole and benzoxazole alanines are disclosed. The compositions have enhanced hypotensive activity.
    Type: Grant
    Filed: February 8, 1977
    Date of Patent: January 17, 1978
    Assignee: Merck & Co., Inc.
    Inventor: Clement A. Stone
  • Novel anti-hypertensive compositions
    Patent number: 4051251
    Abstract: Novel pharmaceutical compositions comprising hydrazino-phenylpropionic acid decarboxylase inhibitors and certain benzimidazole and benzoxazole alanines are disclosed. The compositions have enhanced hypotensive activity.
    Type: Grant
    Filed: February 13, 1976
    Date of Patent: September 27, 1977
    Assignee: Merck & Co., Inc.
    Inventor: Clement A. Stone
  • Antihypertensive agents
    Patent number: 4034100
    Abstract: Compounds of the formula ##STR1## possess antihypertensive activity. Also provided are methods for the preparation of the compounds as well as pharmaceutical formulations and methods for their use as antihypertensive agents.
    Type: Grant
    Filed: February 13, 1976
    Date of Patent: July 5, 1977
    Assignee: Merck & Co., Inc.
    Inventors: Patrick S. Callery, Nicolas Zenker, Jeremy Wright, Clement A. Stone
  • Compositions and method of treating hypertension
    Patent number: 4016288
    Abstract: The present invention relates to a novel and useful method of treatment and a composition which is used to treat hypertension. More particularly, it relates to the administration of a composition containing (A) L-.alpha.-hydrazino-.alpha.-loweralkyl-3,4-dihydroxyphenyl propionic acid or .alpha.-hydrazino-3,4-dihydroxyphenyl propionic acid or a pharmaceutically acceptable non-toxic salt of either in combination with (B) a specific class of esters of .alpha.-methyl-3,4-dihydroxyphenylalaninate or a salt thereof.
    Type: Grant
    Filed: August 13, 1975
    Date of Patent: April 5, 1977
    Assignee: Merck & Co., Inc.
    Inventors: Alexander Scriabine, Clement A. Stone