Patents by Inventor Cleo SALISBURY

Cleo SALISBURY has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • USE OF TRYPTOPHAN DERIVATIVES AND L-METHIONINE FOR PROTEIN FORMULATION
    Publication number: 20210155715
    Abstract: The present disclosure provides methods and formulations comprising a polypeptide comprising solvent accessible amino acid residues susceptible to oxidation wherein N-acetyl-DL-tryptophan (NAT) and/or L-methionine is used to prevent oxidation of the polypeptide.
    Type: Application
    Filed: February 5, 2021
    Publication date: May 27, 2021
    Inventors: Cleo SALISBURY, Vikas SHARMA, Sreedhara ALAVATTAM
  • USE OF TRYPTOPHAN DERIVATIVES FOR PROTEIN FORMULATIONS
    Publication number: 20200246465
    Abstract: The invention provides methods and formulations comprising a protein comprising solvent accessible amino acid residues susceptible to oxidation wherein N-acetyl tryptophan (NAT) is used to prevent oxidation of the protein. The invention also provides methods for making such formulations and methods of using such formulations. Methods to measure degradation of NAT in protein formulations are also provided.
    Type: Application
    Filed: December 20, 2019
    Publication date: August 6, 2020
    Applicant: Genentech, Inc.
    Inventors: Vikas SHARMA, Danielle LEISKE, Lydia HAMBURG, Cleo SALISBURY
  • USE OF TRYPTOPHAN DERIVATIVES FOR PROTEIN FORMULATIONS
    Publication number: 20170239355
    Abstract: The invention provides methods and formulations comprising a protein comprising solvent accessible amino acid residues susceptible to oxidation wherein N-acetyl tryptophan (NAT) is used to prevent oxidation of the protein. The invention also provides methods for making such formulations and methods of using such formulations. Methods to measure degradation of NAT in protein formulations are also provided.
    Type: Application
    Filed: December 28, 2016
    Publication date: August 24, 2017
    Inventors: Vikas SHARMA, Danielle LEISKE, Lydia HAMBURG, Cleo SALISBURY