Patents by Inventor Cliff Berkman

Cliff Berkman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Peptidomimetic inhibitors of PSMA, compounds comprising them, and methods of use
    Patent number: 8293725
    Abstract: Compounds of the formula, A-L-B, wherein A is glutamate or a glutamate analog; L is a phosphoramidate or a phosphoramidate analog; and B is serine or a serine analog are described which are potent inhibitors of prostate-specific membrane antigen (PMSA). Such compounds are useful in treatment of prostate cancer; and when chemically attached to a fluorescent dye, can efficiently and selectively label prostate cancer cells for fluorescent imaging.
    Type: Grant
    Filed: January 22, 2010
    Date of Patent: October 23, 2012
    Assignee: Cancer Targeted Technology LLC
    Inventor: Cliff Berkman
  • Peptidomimetic Inhibitors Of PSMA, Compounds Comprising Them, And Methods Of Use
    Publication number: 20100183517
    Abstract: Compounds of the formula, A-L-B, wherein A is glutamate or a glutamate analog; L is a phosphoramidate or a phosphoramidate analog; and B is serine or a serine analog are described which are potent inhibitors of prostate-specific membrane antigen (PMSA). Such compounds are useful in treatment of prostate cancer; and when chemically attached to a fluorescent dye, can efficiently and selectively label prostate cancer cells for fluorescent imaging.
    Type: Application
    Filed: January 22, 2010
    Publication date: July 22, 2010
    Applicant: CANCER TARGETED TECHNOLOGY LLC
    Inventor: Cliff Berkman
  • Peptidomimetic inhibitors of PSMA, compounds comprising them, and methods of use
    Patent number: 7696185
    Abstract: Compounds of the formula, A—L—B, wherein A is glutamate or a glutamate analog; L is a phosphoramidate or a phosphoramidate analog; and B is serine or a serine analog are described which are potent inhibitors of prostate-specific membrane antigen (PMSA). Such compounds are useful in treatment of prostate cancer; and when chemically attached to a fluorescent dye, can efficiently and selectively label prostate cancer cells for fluorescent imaging.
    Type: Grant
    Filed: March 14, 2007
    Date of Patent: April 13, 2010
    Assignee: Cancer Targered Technology LLC
    Inventor: Cliff Berkman
  • Peptidomimetic Inhibitors Of PSMA, Compounds Comprising Them, And Methods of Use
    Publication number: 20070219165
    Abstract: Compounds of the formula, A-L-B, wherein A is glutamate or a glutamate analog; L is a phosphoramidate or a phosphoramidate analog; and B is serine or a serine analog are described which are potent inhibitors of prostate-specific membrane antigen (PMSA). Such compounds are useful in treatment of prostate cancer; and when chemically attached to a fluorescent dye, can efficiently and selectively label prostate cancer cells for fluorescent imaging.
    Type: Application
    Filed: March 14, 2007
    Publication date: September 20, 2007
    Applicant: CANCER TARGETED TECHNOLOGY LLC
    Inventor: Cliff Berkman