Patents by Inventor Cliff Rowe

Cliff Rowe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CAVITATION-INDUCING BIODEGRADABLE POLYMERIC PARTICLES
    Publication number: 20260207793
    Abstract: The present invention provides a cup-shaped particle comprising a first polymer and a second polymer; wherein the first polymer is a biodegradable polymer; the second polymer is a crosslinked copolymer of two or more different methacrylate monomers and at least one crosslinking agent, wherein the at least one cross-linking agent comprises one or more dimethacrylates; and wherein the cup has a cavity having an opening of at least 50 nm in size.
    Type: Application
    Filed: December 22, 2023
    Publication date: July 23, 2026
    Applicant: Oxsonics Limited
    Inventors: Mohammed Alkattan, Christian Coviello, Cliff Rowe, Charles Pearce
  • COMBINATION THERAPY WITH AN ANTI-AXL ANTIBODY-PBD CONJUGATE AND NANOCUPS
    Publication number: 20250152725
    Abstract: This disclosure relates to therapies in which an antibody drug conjugate is administered together with a composition comprising nanoscale cavitation initiators. Application of ultrasound following administration provides effective, targeted delivery of antibody drug conjugate to the diseased site. The therapies are useful in the treatment of solid tumour.
    Type: Application
    Filed: February 13, 2023
    Publication date: May 15, 2025
    Inventors: Cliff ROWE, Massimo MASIERO, Christian COVIELLO, Patricius Hendrikus Cornelis VAN BERKEL, Jens WUERTHNER
  • LIVER INFECTION
    Publication number: 20160377599
    Abstract: The invention relates to a method for studying an infection process in liver tissue in vitro, the method comprising: seeding hepatocyte cells onto a scaffold in a bioreactor in order to form a liver tissue model;delivering an infectious agent to the liver tissue model, or providing the liver tissue model pre-infected with an infectious agent; and monitoring the infection process; and a method for producing an infectious agent.
    Type: Application
    Filed: July 11, 2014
    Publication date: December 29, 2016
    Inventors: David Hughes, Cliff Rowe, Emma Large, Mark Thursz, Marcus Dorner