Abstract: This invention relates to novel compounds and pharmaceutical compositions comprising. Compounds of the invention useful as modulators of Rho-associated protein kinase (ROCK), for example ROCK1 and/or ROCK2 inhibitors. Methods of treatment employing the compounds are also contemplated by the present invention. The compounds of the invention are useful in treating ROCK mediated diseases.

Abstract: This invention relates to novel compounds and pharmaceutical compositions comprising. Compounds of the invention useful as modulators of Rho-associated protein kinase (ROCK), for example ROCK1 and/or ROCK2 inhibitors. Methods of treatment employing the compounds are also contemplated by the present invention. The compounds of the invention are useful in treating ROCK mediated diseases.

Abstract: This invention relates to novel compounds and pharmaceutical compositions comprising the same. Compounds of the invention useful as modulators of Rho-associated protein kinase (ROCK), for example ROCK1 and/or ROCK2 inhibitors. Methods of treatment employing the compounds are also contemplated by the present invention. The compounds of the invention are useful in treating ROCK mediated diseases.

Abstract: This invention relates to novel compounds and pharmaceutical compositions comprising the same. Compounds of the invention useful as modulators of Rho-associated protein kinase (ROCK), for example ROCK1 and/or ROCK2 inhibitors. Methods of treatment employing the compounds are also contemplated by the present invention. The compounds of the invention are useful in treating ROCK mediated diseases.

Abstract: A locking golf bag has a body portion that includes a tubular wall having an inner surface, an outer surface and an upper edge. A divider plate that has a first opening and a second opening is secured to the tubular wall along the inner surface thereof. The bag also includes a closing member that is coupled to the divider plate and moveable between an open configuration and a closed configuration. The closing member has an outer edge, a first aperture, and a second aperture. When the closing member is in the open configuration, the first aperture is aligned with the first opening such that the first opening has an open size and the second aperture is aligned with the second opening such that the second opening has a first effective size. When the closing member is in the closed configuration, the first aperture is aligned with the first opening such that the first opening has a closed size and the second aperture is aligned with the second opening such that the second opening has a second effective size.

Abstract: A device automatically closes the cover of a container after a predetermined time interval and is used in combination with a timing member, such as a conventional mechanical timer, that includes timer mechanism for measuring a predetermined time interval, a shaft that is rotatable between a de-activated position and an activated position, and an arm that is moveable between an extended position and a retracted position. The device includes a plate member, a first hinge assembly, a first hinge member, a coupling mechanism, a gear, and a connection mechanism. The first hinge assembly includes a cylindrical member that is rotatable in a first direction and a second direction and has a chamber which is sized to receive a portion of the shaft. The hinge member is secured to the cylindrical member and rotates concurrently with the cylindrical member.

Abstract: A collapsible splash guard is provided that is relatively permanently secured to the lower surface of a toilet seat. The splash guard includes a base plate shaped and sized to substantially conform with the shape and size of the toilet bowl rim, a pleated, substantially U-shaped splash shield, and attachment members for attaching a first portion of the splash shield to the base plate. The splash guard also includes pivotal securing members for pivotally securing a second portion of the splash shield to the base plate and members for hingedly attaching the splash guard to the lower face of the toilet seat. The attachment members can either permanently or removable attach the first portion of the splash guard to the base plate. The splash guard can further include a flange which extends downwardly from an inner edge of the base plate such that the attachment members either permanently or removably attach the first portion of the splash shield to an inner face of the flange.