Patents by Inventor Clifford David Jones

Clifford David Jones has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Aminopyrimidine Derivatives With Tie2 Inhibiting Activity
    Publication number: 20080194552
    Abstract: The invention relates to a compound of the Formula I or salt thereof wherein Rx, Ry, Rx, R5, R6, A, B, L, n and m are as defined in the description. The invention also relates to pharmaceutical compositions of said compounds, the use of said compounds as medicaments and in the production of an anti-angiogenic effect in a warm blooded animal. The invention also relates to processes for the preparation of said compounds.
    Type: Application
    Filed: March 30, 2006
    Publication date: August 14, 2008
    Applicant: ASTRAZENECA AB
    Inventors: Clifford David Jones, Richard William, Arthur Luke, William McCoull
  • Compounds Having Tie2 (Tek) Activity
    Publication number: 20080153838
    Abstract: The invention relates to a compound of the Formula I. or salt, prodrug or solvate thereof, wherein R1, R5, R6, D, A, B, L, n, m and p are as defined in the description. The invention also relates to pharmaceutical compositions of said compounds, the use of said compounds as medicaments and in the production of an anti-angiogenic effect in a warm-blooded animal. The invention also relates to processes for the preparation of said compounds.
    Type: Application
    Filed: February 2, 2006
    Publication date: June 26, 2008
    Applicant: ASTRAZENECA AB
    Inventors: Clifford David Jones, Richard Williams Arthur Luke, William McCoull
  • Compounds effecting glucokinase
    Patent number: 7390908
    Abstract: The invention relates to the use of a compound of Formula (I) or a salt, solvate or prodrug thereof, wherein R1, R2, R3, n and m are as described in the specification, in the preparation of a medicament for the treatment or prevention of a disease condition mediated through glucokinase (GLK), such as type 2 diabetes. The invention also relates to a novel group of compounds of Formula (I) and to methods for preparing compounds of Formula (I).
    Type: Grant
    Filed: August 15, 2002
    Date of Patent: June 24, 2008
    Assignee: AstraZeneca AB
    Inventors: Scott Boyd, Peter William Rodney Caulkett, Rodney Brian Hargreaves, Suzanne Saxon Bowker, Roger James, Craig Johnstone, Clifford David Jones, Darren McKerrecher, Michael Howard Block
  • Pyrimidine Compounds Having Tie-2 (Tek) Inhibitory Activity
    Publication number: 20080146599
    Abstract: The invention relates to a compound of the Formula (I) or salt, prodrug or solvate thereof, wherein Rx, Ry, Rz, R5, R6, A, B, L, n and m are as defined in the description. The invention also relates to pharmaceutical compositions of said compounds, the use of said compounds as medicaments and in the production of an anti-angiogenic effect in a warm blooded animal. The invention also relates to processes for the preparation of said compounds.
    Type: Application
    Filed: January 27, 2006
    Publication date: June 19, 2008
    Applicant: ASTRAZENECA AB
    Inventors: Clifford David Jones, Richard William Arthur Luke, William McCoull
  • Pyrimidines With Tie2 (Tek) Activity
    Publication number: 20080108608
    Abstract: The invention relates to a compound of the Formula (I). or salt thereof wherein R1, R2, R3, R4, R5, R6, A, B, L, n and m are as defined in the description. The invention also relates to pharmaceutical compositions of said compounds, the use of said compounds as medicaments and in the production of an anti-angiogenic effect in a warm-blooded animal. The invention also relates to processes for the preparation of said compounds.
    Type: Application
    Filed: December 20, 2004
    Publication date: May 8, 2008
    Applicant: ASTRAZENECA AB
    Inventors: Clifford David Jones, Richard William, Arthur Luke, William McCoull
  • Pyrimidines With Tie2 (Tek) Activity
    Publication number: 20080027076
    Abstract: The invention relates to a compound of the Formula (I); or salt thereof, wherein R1, R2, R3, R4, R5, R6, A, B, L, n and m are as defined in the description. The invention also relates to pharmaceutical compositions of said compounds, the use of said compounds as medicaments and in the production of an anti-angiogenic effect in a warm blooded animal. The invention also relates to processes for the preparation of said compounds.
    Type: Application
    Filed: December 20, 2004
    Publication date: January 31, 2008
    Applicant: ASTRAZENECA AB
    Inventors: Clifford David Jones, Richard William Arthur Luke, William McCoull
  • Amino nicotinate derivatives as glucokinase (GLK) modulators
    Patent number: 7160906
    Abstract: The invention related to novel compounds of Formula (I) or a salt, solvate or prodrug thereof, wherein R1, R2, R3, n and m are as described in the specification, useful in the treatment of a disease or condition mediated through glucokinase (GLK), such as type 2 diabetes. The invention also relates to methods for preparing compounds of Formula (I) and their use as medicaments in the treatment of diseases mediated by glucokinase.
    Type: Grant
    Filed: June 24, 2002
    Date of Patent: January 9, 2007
    Assignee: AstraZeneca AB
    Inventors: Barry Raymond Hayter, Gordon Stuart Currie, Rodney Brian Hargreaves, Roger James, Clifford David Jones, Darren McKerrecher, Joanne Victoria Allen, Peter William Rodney Caulkett, Craig Johnstone, Harold Gaskin
  • Amino nicotinate derivatives as glucokinase (GLK) modulators
    Publication number: 20040214868
    Abstract: The invention related to novel compounds of Formula (I) or a salt, solvate or prodrug thereof, wherein R1, R2, R3, n and m are as described in the specification, useful in the treatment of a 1
    Type: Application
    Filed: June 1, 2004
    Publication date: October 28, 2004
    Inventors: Barry Raymond Hayter, Gordon Stuart Currie, Rodney Brian Hargreaves, Roger James, Clifford David Jones, Darren McKerrecher, Joanne Victoria Allen, Peter William Rodney Caulkett, Craig Johnstone, Harold Gaskin