Patents by Inventor Clifford Hyunsuk Yoon

Clifford Hyunsuk Yoon has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20080248475
    Abstract: The invention provides novel methods and compositions for modulating gluconeogenesis through modulation of PGC-1 activity or expression. Also provided are methods for identifying compounds that modulate gluconeogenesis through modulation of PGC-1 activity or expression, as well as methods for identifying compounds that modulate the interaction of PGC-1 with PGC-1 target molecules. Further provided are methods for treating disorders characterized by aberrant gluconeogenesis.
    Type: Application
    Filed: December 21, 2007
    Publication date: October 9, 2008
    Applicant: Dana-Farber Cancer Institute, Inc.
    Inventors: Bruce M. Spiegelman, Clifford Hyunsuk Yoon
  • Patent number: 7371529
    Abstract: The invention provides novel methods and compositions for modulating gluconeogenesis through modulation of PGC-1 activity or expression. Also provided are methods for identifying compounds that modulate gluconeogenesis through modulation of PGC-1 activity or expression, as well as methods for identifying compounds that modulate the interaction of PGC-1 with PGC-1 target molecules. Further provided are methods for treating disorders characterized by aberrant gluconeogenesis.
    Type: Grant
    Filed: January 6, 2005
    Date of Patent: May 13, 2008
    Assignee: Dana-Farber Cancer Institute, Inc.
    Inventors: Bruce M. Spiegelman, Clifford Hyunsuk Yoon
  • Publication number: 20030099994
    Abstract: Novel FDRG polypeptides, proteins, and nucleic acid molecules are disclosed. In addition to isolated, full-length FDRG proteins, the invention further provides isolated FDRG fusion proteins, antigenic peptides and anti-FDRG antibodies. The invention also provides FDRG nucleic acid molecules, recombinant expression vectors containing a nucleic acid molecule of the invention, host cells into which the expression vectors have been introduced and non-human transgenic animals in which a FDRG gene has been introduced or disrupted. Diagnostic, screening and therapeutic methods utilizing compositions of the invention are also provided.
    Type: Application
    Filed: October 3, 2002
    Publication date: May 29, 2003
    Applicant: Millennium Pharamceuticals, Inc.
    Inventors: Douglas A. Holtzman, Bruce M. Spiegelman, Clifford Hyunsuk Yoon