Patents by Inventor Clifford J. Harris

Clifford J. Harris has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5395853
    Abstract: The present invention is concerned with compounds of formula (I) ##STR1## wherein m is 0 or 1;W is hydrogen, a C.sub.1-16 straight, branched, or cyclic alkyl group, or a C.sub.2-16 straight, branched, or cyclic alkenyl or alkynyl group, orPh(CH.sub.2).sub.n -- where Ph is phenyl and n is an integer of from 0 to 2, the phenyl group being optionally substituted by one or more atoms or groups independently selected from halogen, hydroxy, nitro, C.sub.1-4 alkoxy and C.sub.1-4 alkyl wherein one or more of the hydrogen atoms in said alkyl group is optionally replaced by halogen, orR.sup.1 NHCO-- where R.sup.1 is hydrogen or a C.sub.1-6 alkyl group, orR.sup.2 CONH-- where R.sup.2 is hydrogen or a C.sub.1-6 alkyl group; ##STR2## Y is --(CH.sub.2).sub.q, where q is an integer of from 1 to 3, or --CH.dbd.CH-- (E or Z);Z is a C.sub.
    Type: Grant
    Filed: November 24, 1993
    Date of Patent: March 7, 1995
    Assignee: Burroughs Wellcome Co.
    Inventors: William P. Jackson, Clifford J. Harris, Richard J. Arrowsmith, John G. Dann, Kevin J. O'Connor, Robert F. G. Booth
  • Patent number: 5290814
    Abstract: The present invention is concerned with compounds of formula (I) ##STR1## wherein m is 0 or 1;W is hydrogen, a C.sub.1-16 straight, branched, or cyclic alkyl group, or a C.sub.2-16 straight, branched, or cyclic alkenyl or alkynyl group, or Ph(CH.sub.2).sub.n -- where Ph is phenyl and n is an integer of from 0 to 2, the phenyl group being optionally substituted by one or more atoms or groups independently selected from halogen, hydroxy, nitro, C.sub.1-4 alkoxy and C.sub.1-4 alkyl wherein one or more of the hydrogen atoms in said alkyl group is optionally replaced by halogen, or R.sup.1 NHCO-- where R.sup.1 is hydrogen or a C.sub.1-6 alkyl group, or R.sup.2 CONH-- where R.sup.2 is hydrogen or a C.sub.1-6 alkyl group; X is ##STR2## where A is halogen; Y is --(CH.sub.2).sub.q, where q is an integer of from 1 to 3, or --CH.dbd.CH-- (E or Z);Z is a C.sub.
    Type: Grant
    Filed: November 5, 1992
    Date of Patent: March 1, 1994
    Assignee: Burroughs Wellcome Co.
    Inventors: William P. Jackson, Clifford J. Harris, Richard J. Arrowsmith, John G. Dann, Kevin J. O'Connor, Robert F. G. Booth
  • Patent number: 4537972
    Abstract: Compounds of the general formula ##STR1## wherein the various substituents are defined hereinbelow. These compounds have anti-aggregatory effect on blood platelets and are useful in the treatment or prophylaxis of thrombo-embolic disorders. Processes for the preparation of the compounds are described.
    Type: Grant
    Filed: November 30, 1983
    Date of Patent: August 27, 1985
    Inventors: Clifford J. Harris, Paul Barraclough
  • Patent number: 4432988
    Abstract: Compounds of the general formula ##STR1## [wherein X represents a sulphur atom (--S--) or oxygen atom (--O--) in the .alpha. or .beta.-configuration;X.sup.1 represents a C.sub.1-5 straight chain or branched alkylene group or C.sub.3-5 straight chain or branched alkenylene group;X.sup.2 represents a carboxyl, carboxamide, hydroxymethlene, alkoxycarbonyl or 5-tetrazolyl group;Z represents a hydrogen atom or a C.sub.1-4 straight chain or branched alkyl group;Y represents a group of formula --CR.sub.2 -CH.sub.2 -- in which each R is independently selected from hydrogen and methyl;Y.sup.1 represents a methylene group substituted by hydroxyl, a methylene group substituted by hydroxyl and alkyl, a methylene group or carbonyl group, andY.sup.2 represents a C.sub.1-7 straight chain or branched alkyl group, phenyl, benzyl or a C.sub.4-7 cycloalkyl group] and salts of those compounds of formula (I) wherein X.sup.2 represents a carboxyl group and/or wherein Z represents a hydrogen atom.
    Type: Grant
    Filed: August 25, 1981
    Date of Patent: February 21, 1984
    Assignee: The Wellcome Foundation Ltd.
    Inventors: Clifford J. Harris, Paul Barraclough