Patents by Inventor Clifford S. Deutschman

Clifford S. Deutschman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of using a methylxanthine compound
    Patent number: 9155741
    Abstract: The invention relates to compositions and methods for treating various diseases or medical conditions by administering a methylxanthine compound. Specifically, the invention relates to compositions and methods for treating cytochrome oxidase (CcOX) mediated diseases or medical conditions by administering compositions comprising a methyl xanthine compound.
    Type: Grant
    Filed: June 29, 2009
    Date of Patent: October 13, 2015
    Assignee: The Trustees of the University of Pennsylvania
    Inventors: Clifford S. Deutschman, Richard J. Levy
  • METHODS OF USING A METHYLXANTHINE COMPOUND
    Publication number: 20150246049
    Abstract: The invention relates to compositions and methods for treating various diseases or medical conditions by administering a methylxanthine compound. Specifically, the invention relates to compositions and methods for treating cytochrome oxidase (CcOX) mediated diseases or medical conditions by administering compositions comprising a methyl xanthine compound.
    Type: Application
    Filed: May 15, 2015
    Publication date: September 3, 2015
    Inventors: Clifford S. DEUTSCHMAN, Richard J. LEVY
  • Protein kinase C therapy for the treatment of acute lung injury
    Patent number: 8470766
    Abstract: The present invention provides novel formulations of a ?PKC inhibitor. The ?PKC inhibitor can be, for example, a peptide. The present invention also discloses a method of preventing acute pulmonary cell injury associated with trauma, ALI or ARDS and a method of inhibiting an inflammatory response in pulmonary cells by inhibiting the activity of ?PKC. The invention also provides a method of treating a pulmonary disease with an aerosol formulation of a ?PKC inhibitor to inhibit neutrophil activity.
    Type: Grant
    Filed: June 22, 2009
    Date of Patent: June 25, 2013
    Assignees: The Children's Hospital of Philadelphia, The Trustees of the University of Pennsylvania
    Inventors: Laurie Ellen Kilpatrick, Helen Marie Korchak, Clifford S. Deutschman
  • Methods for the treatment of sepsis and sepsis-associated cardiac dysfunction
    Patent number: 8252281
    Abstract: Methods for the treatment of sepsis related cardiac dysfunction are disclosed.
    Type: Grant
    Filed: February 14, 2006
    Date of Patent: August 28, 2012
    Assignees: The Children's Hospital of Philadelphia, The Trustee of the University of Pennsylvania
    Inventors: Richard J. Levy, Clifford S. Deutschman
  • METHODS OF USING A METHYLXANTHINE COMPOUND
    Publication number: 20120004248
    Abstract: The invention relates to compositions and methods for treating various diseases or medical conditions by administering a methylxanthine compound. Specifically, the invention relates to compositions and methods for treating cytochrome oxidase (CcOX) mediated diseases or medical conditions by administering compositions comprising a methyl xanthine compound.
    Type: Application
    Filed: June 29, 2009
    Publication date: January 5, 2012
    Inventors: Clifford S. Deutschman, Richard J. Levy
  • Novel Protein Kinase C Therapy for the Treatment of Acute Lung Injury
    Publication number: 20100003199
    Abstract: The present invention provides novel formulations of a ?PKC inhibitor. The ?PKC inhibitor can be, for example, a peptide. The present invention also discloses a method of preventing acute pulmonary cell injury associated with trauma, ALI or ARDS and a method of inhibiting an inflammatory response in pulmonary cells by inhibiting the activity of ?PKC. The invention also provides a method of treating a pulmonary disease with an aerosol formulation of a ?PKC inhibitor to inhibit neutrophil activity.
    Type: Application
    Filed: June 22, 2009
    Publication date: January 7, 2010
    Inventors: Laurie Ellen Kilpatrick, Helen Marie Korchak, Clifford S. Deutschman
  • Methods for the Treatment of Sepsis and Sepsis-Associated Cardiac Dysfunction
    Publication number: 20090024105
    Abstract: Methods for the treatment of sepsis related cardiac dysfunction are disclosed.
    Type: Application
    Filed: February 14, 2006
    Publication date: January 22, 2009
    Inventors: Richard J. Levy, Clifford S. Deutschman
  • Method of preventing acute pulmonary cell injury
    Publication number: 20020198139
    Abstract: The present invention discloses a method of preventing acute pulmonary cell injury associated with ALI or ARDS and a method of inhibiting an inflammatory response in pulmonary cells by increasing levels of HSP70 protein.
    Type: Application
    Filed: May 16, 2002
    Publication date: December 26, 2002
    Inventors: Clifford S. Deutschman, Veram Weiss