Patents by Inventor Clifford S. Schold

Clifford S. Schold has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of depletion of methionine in plasma and solid tumors and uses thereof
    Patent number: 6017962
    Abstract: The present invention provides a method of depleting methionine in the plasma of an individual in need of such treatment, comprising the steps of: administering to said individual a pharmacologically effective amount of a methionine scavenger; and treating said individual with homocystine. Also provided is a method of method of treating a methionine-dependent tumor in an individual in need of such treatment, comprising the steps of: administering to said individual a pharmacologically effective amount of a methionine synthetase inhibitor; treating said individual with homocystine while depriving dietary methionine, homocysteine and choline; and administering to said individual a pharmacologically effective amount of an anti-neoplastic alkylating agent.
    Type: Grant
    Filed: February 27, 1997
    Date of Patent: January 25, 2000
    Assignee: Board of Regents, The University of Texas System
    Inventors: Clifford S. Schold, Demetrius M. Kokkinakis