Patents by Inventor Clifford Tabin

Clifford Tabin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Hedgehog antibodies
    Patent number: 7901686
    Abstract: The present invention concerns the discovery that proteins encoded by a family of vertebrate genes, termed here hedgehog-related genes, comprise morphogenic signals produced by embryonic patterning centers, and are involved in the formation of ordered spatial arrangements of differentiated tissues in vertebrates. The present invention makes available compositions and methods that can be utilized, for example to generate and/or maintain an array of different vertebrate tissue both in vitro and in vivo.
    Type: Grant
    Filed: August 3, 2005
    Date of Patent: March 8, 2011
    Assignees: President and Fellows of Harvard College, Imperial Cancer Research Technology Ltd.
    Inventors: Clifford Tabin, Valeria Marigo, Philip W. Ingham, Andrew P. McMahon
  • Screening assays for hedgehog agonists and antagonists
    Publication number: 20080171328
    Abstract: The present invention concerns the discovery that proteins encoded by a family of vertebrate genes, termed here hedgehog-related genes, comprise morphogenic signals produced by embryonic patterning centers, and are involved in the formation of ordered spatial arrangements of differentiated tissues in vertebrates. The present invention makes available compositions and methods that can be utilized, for example to generate and/or maintain an array of different vertebrate tissue both in vitro and in vivo.
    Type: Application
    Filed: August 20, 2007
    Publication date: July 17, 2008
    Applicants: The President and Fellows of Harvard College, Imperial Cancer Research Technology Limited
    Inventors: Clifford Tabin, Valeria Marigo, Philip W. Ingham, Andrew P. McMahon
  • Vertebrate embryonic pattern-inducing proteins, and uses related thereto
    Publication number: 20070213273
    Abstract: The present invention concerns the discovery that proteins encoded by a family of vertebrate genes, termed here hedgehog-related genes, comprise morphogenic signals produced by embryonic patterning centers, and are involved in the formation of ordered spatial arrangements of differentiated tissues in vertebrates. The present invention makes available compositions and methods that can be utilized, for example to generate and/or maintain an array of different vertebrate tissue both in vitro and in vivo.
    Type: Application
    Filed: December 5, 2006
    Publication date: September 13, 2007
    Inventors: Philip Ingham, Andrew McMahon, Clifford Tabin
  • Screening assays for agonists and antagonists of the hedgehog signaling pathway
    Patent number: 7060450
    Abstract: The present invention concerns the discovery that proteins encoded by a family of vertebrate genes, termed here hedgehog-related genes, comprise morphogenic signals produced by embryonic patterning centers, and are involved in the formation of ordered spatial arrangements of differentiated tissues in vertebrates. The present invention makes available compositions and methods that can be utilized, for example to generate and/or maintain an array of different vertebrate tissue both in vitro and in vivo.
    Type: Grant
    Filed: November 13, 2000
    Date of Patent: June 13, 2006
    Assignees: President and Fellows of Harvard College, Imperial Cancer Research Technology Ltd.
    Inventors: Clifford Tabin, Valeria Marigo, Philip W. Ingham, Andrew P. McMahon
  • Screening assays for hedgehog agonists and antagonists
    Publication number: 20050282231
    Abstract: The present invention concerns the discovery that proteins encoded by a family of vertebrate genes, termed here hedgehog-related genes, comprise morphogenic signals produced by embryonic patterning centers, and are involved in the formation of ordered spatial arrangements of differentiated tissues in vertebrates. The present invention makes available compositions and methods that can be utilized, for example to generate and/or maintain an array of different vertebrate tissue both in vitro and in vivo.
    Type: Application
    Filed: August 3, 2005
    Publication date: December 22, 2005
    Inventors: Clifford Tabin, Valeria Marigo, Philip Ingham, Andrew McMahon
  • Vertebrate embryonic pattern-inducing proteins and uses related thereto
    Publication number: 20050004028
    Abstract: The present invention concerns the discovery that proteins encoded by a family of vertebrate genes, termed here hedgehog-related genes, comprise morphogenic signals produced by embryonic patterning centers, and are involved in the formation of ordered spatial arrangements of differentiated tissues in vertebrates. The present invention makes available compositions and methods that can be utilized, for example to generate and/or maintain an array of different vertebrate tissue both in vitro and in vivo.
    Type: Application
    Filed: April 28, 2004
    Publication date: January 6, 2005
    Applicants: President and Fellows of Harvard College, Imperial Cancer Research Technology Limited
    Inventors: Philip Ingham, Andrew McMahon, Clifford Tabin