Patents by Inventor Clifford William Coughlin

Clifford William Coughlin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Scalable process for the preparation of a rapamycin 42-ester from a rapamycin 42-ester boronate
    Patent number: 7622578
    Abstract: A scalable process for the preparation of a rapamycin 42-ester by reacting a rapamycin 42-ester boronate with a diol and purifying crude rapamycin 42-ester by recrystallization and treatment with a diol is provided. Also provided is a method for isolating and purifying a rapamycin 42-ester boronate from mother liquors comprising acetone and rapamycin contaminants.
    Type: Grant
    Filed: December 6, 2006
    Date of Patent: November 24, 2009
    Assignee: Wyeth
    Inventors: Chunhao Zhang, Clifford William Coughlin, Anthony Pilcher, Adam P. Michaud, James S. Farina, Ayman Sahli
  • Process for the preparation of purified crystalline CCI-779
    Patent number: 7553843
    Abstract: The present invention provides purified crystalline CCI-779 and processes for preparing the same.
    Type: Grant
    Filed: December 6, 2006
    Date of Patent: June 30, 2009
    Assignee: Wyeth
    Inventors: Subodh S. Deshmukh, Clifford William Coughlin, Chunhao Zhang, Adam P. Michaud, Lynn M. Phelan, Wei Tong