Abstract: A dinghy constructed of two separable sections, being a front and a rear section, and a connection means adapted to join the two sections together. The front section has a rear bulkhead, the rear section has a front bulkhead the connection means integral with the bulkheads. One of the bulkheads includes cylindrical sleeves, the other bulkhead cylindrical rods adapted to engage the sleeves to thereby connect the dinghy together.

Abstract: Provided herein is a method for the synthesis of cephalosporin antibiotic compounds comprising a palladium-catalyzed coupling reaction.

Abstract: Provided herein is a method for the synthesis of cephalosporin antibiotic compounds comprising a palladium-catalyzed coupling reaction.

Abstract: Provided herein is a method for the synthesis of cephalosporin antibiotic compounds comprising a palladium-catalyzed coupling reaction.

Abstract: A dinghy constructed of two separable sections, being a front and a rear section, and a connection means adapted to join the two sections together. The front section has a rear bulkhead, the rear section has a front bulkhead the connection means integral with the bulkheads. One of the bulkheads includes sleeves, the other bulkhead rods adapted to engage the sleeves to thereby connect the dinghy together.

Abstract: Provided herein is a method for the synthesis of cephalosporin antibiotic compounds comprising a palladium-catalyzed coupling reaction.

Abstract: Provided herein is a method for the synthesis of cephalosporin antibiotic compounds comprising a palladium-catalyzed coupling reaction. Provided herein are methods for the synthesis of cephalosporin compounds of formula (I) employing a palladium-catalyzed alkylation reaction, as well as compositions related to the same. In an aspect, provided herein is a method for preparing a compound of formula (II), or a salt thereof, comprising the step of admixing, e.g., reacting, a compound of formula (III), or a salt thereof, with a nucleophile (Nuc) in the presence of reagents comprising: (a) a palladium source; and (b) a palladium-binding ligand, to form a compound of formula (II), or a salt thereof.

Abstract: The present invention generally relates to a process for preparation of 9-halo-3-(2-haloacetyl)-10,11-dihydro-5H-dibenzo[c,g]chromen-8(9H)-one of Formula I, which is an intermediate in the preparation of Hepatitis C Virus (HCV) inhibitors.

Abstract: The present invention generally relates to a process for preparation of 9-halo-3-(2-haloacetyl)-10,11-dihydro-5H-dibenzo[c,g]chromen-8(9H)-one of Formula I, which is an intermediate in the preparation of Hepatitis C Virus (HCV) inhibitors.

Abstract: Provided herein is a method for the synthesis of cephalosporin antibiotic compounds comprising a palladium-catalyzed coupling reaction. Provided herein are methods for the synthesis of cephalosporin compounds of formula (I) employing a palladium-catalyzed alkylation reaction, as well as compositions related to the same. In an aspect, provided herein is a method for preparing a compound of formula (II), or a salt thereof, comprising the step of admixing, e.g., reacting, a compound of formula (III), or a salt thereof, with a nucleophile (Nuc) in the presence of reagents comprising: (a) a palladium source; and (b) a palladium-binding ligand, to form a compound of formula (II), or a salt thereof.

Abstract: The present invention provides for a device for sealing paint in a can. The device or fluid cover includes a circular disk having an outer edge with the diameter of the edge being smaller than the inner diameter of the can. The cover includes a side wall that extends outwardly and upwardly and a lip that extends radially outwardly from the side wall. The diameter of the lip is greater than the inner diameter of the can. Upon insertion of the cover into the can the side wall flexes to allow the cover to be inserted into the can, whilst the lip frictionally engages the can inner surface. The fluid cover further includes a handle defining an upward cavity that can be compressed to expel air from the cavity and assists in sealing the fluid cover on top of paint by providing a partial vacuum. The side wall may be of an arcuate shape and have several sections extending radially outwardly at different angles to the disk.

Abstract: The present invention provides for a device for sealing paint in a can. The device or fluid cover includes a circular disk having an outer edge with the diameter of the edge being smaller than the inner diameter of the can. The cover includes a side wall that extends outwardly and upwardly and a lip that extends radially outwardly from the side wall. The diameter of the lip is greater than the inner diameter of the can. Upon insertion of the cover into the can the side wall flexes to allow the cover to be inserted into the can, whilst the lip frictionally engages the can inner surface. The fluid cover further includes a handle defining an upward cavity that can be compressed to expel air from the cavity and assists in sealing the fluid cover on top of paint by providing a partial vacuum. The side wall may be of an arcuate shape and have several sections extending radially outwardly at different angles to the disk.