Patents by Inventor Clint James

Clint James has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pyrrolotriazine compounds and methods of inhibiting TAM kinases
    Patent number: 11040981
    Abstract: Described herein are compounds, methods of making such compounds, pharmaceutical compositions, and medicaments comprising such compounds, and methods of using such compounds to treat cancer.
    Type: Grant
    Filed: October 9, 2018
    Date of Patent: June 22, 2021
    Assignee: Syros Pharmaceuticals, Inc.
    Inventors: David Moebius, Jason J. Marineau, Yi Zhang, Claudio Edmundo Chuaqui, Goran Malojcic, William Sinko, Huiping Amy Guan, Stephane Ciblat, Clint James, Amandine Xolin, Sylvain Bernard, Malay Doshi
  • PYRROLOTRIAZINE COMPOUNDS AND METHODS OF INHIBITING TAM KINASES
    Publication number: 20210147431
    Abstract: Described herein are compounds, methods of making such compounds, pharmaceutical compositions, and medicaments comprising such compounds, and methods of using such compounds to treat cancer.
    Type: Application
    Filed: October 22, 2020
    Publication date: May 20, 2021
    Inventors: David Moebius, Jason J. Marineau, Yi Zhang, Claudio Edmundo Chuaqui, Goran Malojcic, William Sinko, Huiping Amy Guan, Stephane Ciblat, Clint James, Amandine Xolin, Sylvain Bernard, Malay Doshi
  • PYRROLOTRIAZINE COMPOUNDS AND METHODS OF INHIBITING TAM KINASES
    Publication number: 20200317676
    Abstract: Described herein are compounds, methods of making such compounds, pharmaceutical compositions, and medicaments comprising such compounds, and methods of using such compounds to treat cancer.
    Type: Application
    Filed: October 9, 2018
    Publication date: October 8, 2020
    Applicant: Syros Pharmaceuticals, Inc.
    Inventors: David Moebius, Jason J. Marineau, Yi Zhang, Kathryn Austgen, Claudio Edmundo Chuaqui, Goran Malojcic, William Sinko, Huiping Amy Guan, Tracey Lodie Savoie, Stephane Ciblat, Clint James, Amandine Xolin, Sylvain Bernard, Malay Doshi
  • TAM KINASE INHIBITORS
    Publication number: 20200291018
    Abstract: Described herein are compounds, methods of making such compounds, pharmaceutical compositions, and medicaments comprising such compounds, and methods of using such compounds to treat diseases, such as cancer.
    Type: Application
    Filed: July 13, 2018
    Publication date: September 17, 2020
    Applicant: Syros Pharmaceuticals, Inc.
    Inventors: Yi ZHANG, Claudio Edmundo CHUAQUE, Goran MALOJCIC, William SINKO, Stephane CIBLAT, Clint JAMES, Huiping Amy GUAN, Jason J. MARINEAU, David MOEBIUS
  • Inhibitors of HIV replication
    Patent number: 9399645
    Abstract: Compounds of formula (I) and pharmaceutical compositions thereof: wherein A1 A2 and A3 are each independently selected from the group consisting of N and CR3, wherein R1 is an optionally substituted heterocyclyl or an optionally substituted —(C1-6)alkyl-heterocyclyl, R2 is an optionally substituted aryl or an optionally subsisted heteroaryl, R4 is an optionally substituted aryl, an optionally substituted heterocyclyl or an optionally substituted heteroaryl, useful as an inhibitor of HIV replication.
    Type: Grant
    Filed: December 19, 2012
    Date of Patent: July 26, 2016
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Claudio Sturino, Pierre Beaulieu, Patrick Deroy, Martin Duplessis, Clint James, Jean-Eric Lacoste, Joannie Minville, Louis Morency, Sébastien Morin, Bruno Simoneau, Martin Tremblay
  • Inhibitors of cytomegalovirus
    Patent number: 9334249
    Abstract: Compounds of Formula (I) wherein n, R1, R1A, R2, R4 and Z are defined herein, are useful for the treatment of cytomegalovirus disease and/or infection.
    Type: Grant
    Filed: October 31, 2013
    Date of Patent: May 10, 2016
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Lee Fader, Mathieu Parisien, Carl Thibeault, Louis Morency, Martin Duplessis, Clint James, Sébastien Morin, James Gillard
  • INHIBITORS OF CYTOMEGALOVIRUS
    Publication number: 20150284348
    Abstract: Compounds of Formula (I) wherein n, R1, R1A, R2, R4 and Z are defined herein, are useful for the treatment of cytomegalovirus disease and/or infection.
    Type: Application
    Filed: October 31, 2013
    Publication date: October 8, 2015
    Inventors: Lee Fader, Mathieu Parisien, Carl Thibeault, Louis Morency, Martin Duplessis, Clint James, Sébastien Morin, James Gillard
  • INHIBITORS OF HIV REPLICATION
    Publication number: 20150011531
    Abstract: Compounds of formula (I) and pharmaceutical compositions thereof: wherein A1 A2 and A3 are each independently selected from the group consisting of N and CR3, wherein R1 is an optionally substituted heterocyclyl or an optionally substituted —(C1-6)alkyl-heterocyclyl, R2 is an optionally substituted aryl or an optionally subsisted heteroaryl, R4 is an optionally substituted aryl, an optionally substituted heterocyclyl or an optionally substituted heteroaryl, useful as an inhibitor of HIV replication.
    Type: Application
    Filed: December 19, 2012
    Publication date: January 8, 2015
    Applicant: Boehringer Ingelheim International GmbH
    Inventors: Claudio Sturino, Pierre Beaulieu, Patrick Deroy, Martin Duplessis, Clint James, Jean-Eric Lacoste, Joannie Minville, Louis Morency, Sébastien Morin, Bruno Simoneau, Martin Tremblay
  • Inhibitors of HIV replication
    Patent number: 8349839
    Abstract: Compounds of formula (I): wherein R1, R2, A1, A2, A3, A4, X and Y are as defined herein, are useful as inhibitors of HIV replication.
    Type: Grant
    Filed: April 8, 2010
    Date of Patent: January 8, 2013
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Claudio Sturino, Patrick Deroy, Martin Duplessis, Paul J. Edwards, Anne-Marie Faucher, Teddy Halmos, Clint James, Jean-Eric Lacoste, Eric Malenfant, Joannie Minville, Louis Morency, Sebastien Morin, Martin Tremblay, Christiane Yoakim
  • INHIBITORS OF HIV REPLICATION
    Publication number: 20100261714
    Abstract: Compounds of formula (I): wherein R1, R2, A1, A2, A3, A4, X and Y are as defined herein, are useful as inhibitors of HIV replication.
    Type: Application
    Filed: April 8, 2010
    Publication date: October 14, 2010
    Applicant: BOEHRINGER INGELHEIM INTERNATIONAL GMBH
    Inventors: Claudio STURINO, Patrick DEROY, Martin DUPLESSIS, Paul J. EDWARDS, Anne-Marie FAUCHER, Teddy HALMOS, Clint JAMES, Jean-Eric LACOSTE, Eric MALENFANT, Joannie MINVILLE, Louis MORENCY, Sebastien MORIN, Martin TREMBLAY, Christiane YOAKIM
  • Piperazine amidines as antiviral agents
    Publication number: 20070078141
    Abstract: This disclosure provides compounds of Formula I as described herein having drug and bio-affecting properties, their pharmaceutical compositions and method of use. In particular, the disclosure is concerned with indole and azaindole piperazine diamide derivatives that possess unique antiviral activity. More particularly, the present disclosure relates to compounds useful for the treatment of HIV and AIDS.
    Type: Application
    Filed: October 2, 2006
    Publication date: April 5, 2007
    Inventors: Tao Wang, John Kadow, Nicholas Meanwell, Zhongxing Zhang, Zhiwei Yin, Clint James, Edward Ruediger, Bradley Pearce