Patents by Inventor Clive A. SMITH
Clive A. SMITH has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11957827Abstract: A sample holder for use in a centrifuge, the sample holder being generally planar and comprising: an aperture or recess for releasably retaining a sample storage member including a sample chamber adapted to contain a volume of liquid; a centre point around which the holder will rotate during use; and one or more calibration features, wherein the calibration feature(s) comprise one or more outer edges, which lie on the side of the or each calibration feature which is furthest from the centre point, and the one or more outer edges comprise a series of radially spaced-apart outer edge portions or positions which are spaced at different distances from the centre point as a function of angular position around the centre point.Type: GrantFiled: October 10, 2017Date of Patent: April 16, 2024Assignee: Entia LimitedInventors: Millie Clive-Smith, Toby Basey-Fisher
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Patent number: 11820863Abstract: The present invention provides a surfactant having a formula selected from the group consisting of: B—((X)x—(CH2)a-A)n(VI), (A-(CH2)a—(X)x—B—(X)x—(CH2)a-A)n (IV), (A-(CH2)a—(X)x—B)n (V), and (B)n—(X)x—(CH2)a-A (VII), wherein A is a perfluoropolyether; a is a positive integer; X is either a covalent bond or a linking group; x is a positive integer; B is a polyalkylene oxide unit; n is a positive integer greater than 1 and, in compounds comprising more than one A, B, X, a and x, each may be the same or different. The present invention also relates to methods of making such surfactants, uses of such surfactants and emulsions comprising such surfactants.Type: GrantFiled: May 26, 2017Date of Patent: November 21, 2023Assignee: SPHERE FLUIDICS LIMITEDInventors: Xin Li, Clive A. Smith, Alexandra Clay, Frank F. Craig
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Publication number: 20230193137Abstract: The present invention provides a surfactant of formula (I): (A)m-X-(B)n (I) wherein X is a linking group; each A is N independently a fluorocarbon or a perfluoropolyether; each B is independently (II) wherein a is an integer between 3 and 50 and each R is independently C1-6 alkyl, CH2CH2OC1-6 alkyl or CH2CH(CH3)OC1-6 alkyl; m is an integer between 1 and 10; and n is an integer between 1 and 10.Type: ApplicationFiled: May 4, 2021Publication date: June 22, 2023Inventors: Xin LI, Clive Smith, Ben Mackworth
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Patent number: 11661269Abstract: A support structure for supporting vehicles one above the other during transport or storage, the structure comprising a base frame having four corner posts extending generally vertically when in use to support a separate upper frame on which an upper vehicle can be supported in an elevated transport position, and one or more separate lower frames arranged to be positioned within the base frame when in use on which a lower vehicle can be supported. The upper frame is guided up the corner posts when the upper vehicle is raised to the elevated transport position. The base frame, upper and lower frames are transportable in a collapsed state when not in use by folding the corner posts down and collapsing the base frame, upper frame and lower frame so that they occupy less space with the upper, and lower and base frames in a nested configuration.Type: GrantFiled: March 23, 2018Date of Patent: May 30, 2023Assignee: Trans-Rak International LimitedInventors: Wesley Payne, Martin Clive-Smith
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Publication number: 20220228652Abstract: Embodiments of this disclosure are directed to devices that allow for adjusting of device parameters in a manner that does not involve power dissipation in an essential way. Thus, power demands when such devices are used in applications can be insignificant. This applies to both springs and inerters, which constitute basic lossless building blocks of mechanical device systems, and are analogues of inductors and capacitors in electrical circuits. Embodiments of this disclosure are also directed to a lossless adjustable 2-port transformer, and realization of mechanical translational and rotary transformers are set forth in the following. Embodiments of this disclosure allow for reduction of power demands in adjusting device parameters.Type: ApplicationFiled: May 13, 2020Publication date: July 21, 2022Applicants: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, CAMBRIDGE ENTERPRISE LIMITEDInventors: Tryphon T. Georgiou, Malcolm Clive Smith, Faryar Jabbari, Neil E. Houghton
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Publication number: 20220194693Abstract: A rig for connecting or disconnecting container couplers to or from the four lower corner fittings of a shipping container, the rig has two pairs of corner units held in the required transverse special relationship by a structure extending between the two corner units of each pair to form two operating end modules. A base member has sockets and/or other connectors to secure the operating end modules in a plurality of longitudinal special relationships to enable the corner units of the modules to simultaneously engage all the four lower corner fittings of a range of containers of different lengths or using different types of couplers. Each corner unit includes an Indexing means for engaging and manipulating an associated coupling to connect or disconnect the coupling to or from its associated container corner fitting.Type: ApplicationFiled: February 11, 2020Publication date: June 23, 2022Inventors: Martin Clive-Smith, Edward Henry Reynolds, James Clive-Smith
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Patent number: 11287365Abstract: A cuvette comprising: a main body having a sample chamber formed therein, the sample chamber communicating with the exterior of the cuvette by an opening formed in the exterior of the main body, wherein the sample chamber comprises a first sample chamber and a second sample chamber, the first sample chamber being in fluid communication with the opening, and the second sample chamber having a first end which is in fluid communication with the first sample chamber, and a second, closed end, the second sample chamber being in fluid communication with the exterior of the cuvette only through the first chamber, the first chamber having a width which is greater than that of the second chamber, and further wherein the greatest width of the opening is greater than or equal to the greatest width of the first sample chamber, the greatest width of the first sample chamber is greater than or equal to the greatest width of the second sample chamber, and the width of the sample chamber, passing from the opening to the closType: GrantFiled: October 9, 2017Date of Patent: March 29, 2022Assignee: Entia LimitedInventors: Millie Clive-Smith, Toby Basey-Fisher
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Publication number: 20210308682Abstract: We describe instruments, and cartridges therefor, for processing droplets of water in oil-in-water emulsions, the droplets containing biological entities such as cells. In one embodiment a method of such processing comprises: providing a plurality of the entities in a fluid: preparing a droplet from said fluid: determining whether said droplet contains one or more entities of said plurality of entities, or whether said droplet does not contain a said entity; sorting said droplet dependent on an outcome of said determination; and dispensing said sorted droplet into a reservoir, wherein said dispensing comprises: identifying said sorted droplet for dispensing; extracting said sorted droplet from a first fluidic flow path of said fluid by transferring said sorted droplet from said first fluidic flow path into a second fluidic flow path; and ejecting said sorted droplet from said second fluidic flow path into said reservoir by applying pressure to said second fluidic flow path.Type: ApplicationFiled: June 16, 2021Publication date: October 7, 2021Inventors: Frank F. CRAIG, Marian Rehak, David Holmes, Clive A. Smith, Xin Liu, Giuseppe Benazzi, Xin Li, Vinayaka Pawate, Robert Frank Marchington, Richard Francis Day, Michael Stewart Hazell
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Patent number: 11124391Abstract: An adaptor including a pair of lifting beams for lifting two or more shipping containers in a side by side configuration, each container having corner fittings provided with lifting/fastening sockets. Each lifting beam is designed to extend across one end of the top of the containers to be lifted and has pairs of connectors designed to connect to the lifting sockets provided in the tops of the containers. Each lifting beam, or connecting beams extending between the lifting beams, have sockets for detachable connection with an associated crane or lifting machine to lift the adaptor and containers. Each lifting beam is also a continuous extendable component having first and second portions which are movable relative to each other.Type: GrantFiled: February 8, 2018Date of Patent: September 21, 2021Assignee: BLOK Container Systems LimitedInventors: Martin Clive-Smith, Edward Henry Reynolds
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Publication number: 20210245999Abstract: A method of testing a shipping container (10) for use as an upper container in a vertical tandem lift configuration the method comprising supporting the container other than by the lower corner fittings (15), connecting couplers (18) in the lower corner fittings of the container to be tested and then applying a proof load on the couplers to confirm that the container and/or the couplers can sustain the forces at least through the lower corner fittings which will be experienced during use in a vertical tandem lift. The invention also provides a rig (70, 143) for carrying out the proof test and/or for connecting or disconnecting couplers to or from the lower corner fittings of a shipping container. Various corner units for use in such a rig are also disclosed.Type: ApplicationFiled: May 8, 2019Publication date: August 12, 2021Inventor: Martin Clive-Smith
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Patent number: 11077441Abstract: Instruments and cartridges for processing droplets in emulsions containing biological entities such as cells. A method of such processing comprises providing a plurality of the entities in a fluid; preparing a droplet from the fluid; determining whether the droplet contains one or more entities of said plurality of entities, or whether said droplet does not contain a said entity; sorting said droplet dependent on an outcome of the determination; and dispensing the sorted droplet into a reservoir. The dispensing may comprise identifying and extracting the sorted droplet from a first fluidic flow path of said fluid by transferring the sorted droplet from into a second fluidic flow path and then ejecting the sorted droplet into a reservoir by applying pressure to the second fluidic flow path. The droplet contents may be tracked so that the contents of an individual droplet can be sorted, selectively dispensed, and retrieved.Type: GrantFiled: June 3, 2016Date of Patent: August 3, 2021Assignee: Sphere Fluidics LimitedInventors: Frank F. Craig, Marian Rehak, David Holmes, Clive A. Smith, Xin Liu, Giuseppe Benazzi, Xin Li, Vinayaka Pawate, Robert Frank Marchington, Richard Francis Day, Michael Stuart Hazell
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Patent number: 11000162Abstract: A multi-ply fibrous product includes at least two fibrous plies, such as a multi-ply nonwoven product, a tissue paper product or a hybrid thereof including at least two tissue paper plies and/or nonwoven plies including cellulosic fibers. At least two fibrous plies are bonded to each other by an aqueous adhesive composition including an adhesive component and a dermatologically acceptable acid, and optionally a salt thereof. A process for the manufacture of this multi-ply fibrous product includes (a) providing at least two fibrous webs, (c) applying an aqueous adhesive composition including an adhesive component and a water-soluble, dermatologically acceptable acid, and optionally the corresponding salt thereof, to at least one side of at least one fibrous web, d) superimposing at least two webs such that the aqueous adhesive composition is located between at least two superimposed webs, and e) bonding at least two webs together.Type: GrantFiled: January 27, 2016Date of Patent: May 11, 2021Assignee: Essity Hygiene and Health AktiebolagInventors: Pascale Saas, Emilie Pleyber, Daniel Hagberg, Alain Bohn, Frédéric Roesch, Yves Enggasser, Clive Smith
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Publication number: 20200354198Abstract: A system for lifting shipping containers each having corner fittings provided with lifting/fastening apertures, the system including lifting means for lifting en masse a matrix of containers including two or more columns of vertically connected containers, each column being at least two containers high. The lifting means uses the lifting apertures provided on the top of the top container in each column, and connecting means are provided for connecting each column transversely to each adjacent column to hold the columns together and prevent toppling of the columns relative to each other. A method of lifting is also disclosed together with a lifting beam and trailer and for use in handling containers.Type: ApplicationFiled: February 17, 2017Publication date: November 12, 2020Applicant: Blok Container Systems LimitedInventors: Martin CLIVE-SMITH, John EVANS
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Publication number: 20200338271Abstract: Fill-finish assemblies facilitating the manufacture of a drug delivery device are disclosed. The fill-finish assembly may include a container, an insertion mechanism, a fluid pathway connection assembly disposed between the container and the insertion mechanism, and a carrier. The insertion mechanism may include a delivery member and an insertion mechanism housing. The insertion mechanism may be configured to move the delivery member from a retracted position inside the insertion mechanism housing to a deployed position outside the insertion mechanism housing. The fluid pathway connection assembly may be selectively activatable to establish fluid communication between the container and the delivery member. The carrier may have a hollow interior containing at least a portion of each of the container, the insertion mechanism, and the fluid pathway connection assembly.Type: ApplicationFiled: November 6, 2018Publication date: October 29, 2020Applicant: AMGEN INC.Inventors: Justin Harris, Matthew Wayne Janke, Wael Mismar, Jerome Olivas, Thomas Clark Pearson, Sudeshna Dutta Ray, Ryan M. Agard, Alexis Dechelette, Michael Gammelager, Mads Hansen, Valerio Mazzon, Owen Ryan, Clive Smith
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Publication number: 20200316545Abstract: A surfactant of formula (I): A-(L1)a-(C2)b-(L2)c-X ??(I) wherein A is a perfluoropolyether; L1 is CONR', wherein R? is selected from H and C1-6 alkyl; a is 0 or 1; b is 0 or an integer between 1 and 10; L2 is a linking group; c is 0 or 1; and X is a charged group.Type: ApplicationFiled: November 29, 2018Publication date: October 8, 2020Inventors: Xin LI, Clive A. SMITH, Alexandra CLAY, Colin PILKINGTON
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Publication number: 20200209145Abstract: A cuvette comprising: a main body having a sample chamber formed therein, the sample chamber communicating with the exterior of the cuvette by an opening formed in the exterior of the main body, wherein the sample chamber comprises a first sample chamber and a second sample chamber, the first sample chamber being in fluid communication with the opening, and the second sample chamber having a first end which is in fluid communication with the first sample chamber, and a second, closed end, the second sample chamber being in fluid communication with the exterior of the cuvette only through the first chamber, the first chamber having a width which is greater than that of the second chamber, and further wherein the greatest width of the opening is greater than or equal to the greatest width of the first sample chamber, the greatest width of the first sample chamber is greater than or equal to the greatest width of the second sample chamber, and the width of the sample chamber, passing from the opening to the closType: ApplicationFiled: October 9, 2017Publication date: July 2, 2020Inventors: Millie Clive-Smith, Toby Basey-Fisher
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Publication number: 20200102143Abstract: A support structure for supporting vehicles one above the other during transport or storage, the structure comprising a base frame having four corner posts extending generally vertically when in use to support a separate upper frame on which an upper vehicle can be supported in an elevated transport position, and one or more separate lower frames arranged to be positioned within the base frame when in use on which a lower vehicle can be supported. The upper frame is guided up the corner posts when the upper vehicle is raised to its upper transport position and support means associated with the corner posts fasten the upper frame in its transport position relative to the corner posts. The base frame, upper and lower frames are transportable in a collapsed state when not in use by folding the corner posts down and collapsing the base frame, upper frame and lower frame so that they occupy less space with the upper, and lower and base frames in a nested configuration.Type: ApplicationFiled: March 23, 2018Publication date: April 2, 2020Inventors: Wesley Payne, Martin Clive-Smith
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Publication number: 20200054819Abstract: A sample holder for use in a centrifuge, the sample holder being generally planar and comprising: an aperture or recess for releasably retaining a sample storage member including a sample chamber adapted to contain a volume of liquid; a centre point around which the holder will rotate during use; and one or more calibration features, wherein the calibration feature(s) comprise one or more outer edges, which lie on the side of the or each calibration feature which is furthest from the centre point, and the one or more outer edges comprise a series of radially spaced-apart outer edge portions or positions which are spaced at different distances from the centre point as a function of angular position around the centre point.Type: ApplicationFiled: October 10, 2017Publication date: February 20, 2020Inventors: Millie Clive-Smith, Toby Basey-Fisher
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Publication number: 20200055711Abstract: An adaptor including a pair of lifting beams for lifting two or more shipping containers in a side by side configuration, each container having corner fittings provided with lifting/fastening sockets. Each lifting beam is designed to extend across one end of the top of the containers to be lifted and has pairs of connectors designed to connect to the lifting sockets provided in the tops of the containers. Each lifting beam, or connecting beams extending between the lifting beams, have sockets for detachable connection with an associated crane or lifting machine to lift the adaptor and containers. Each lifting beam is also a continuous extendable component having first and second portions which are movable relative to each other.Type: ApplicationFiled: February 8, 2018Publication date: February 20, 2020Inventors: Martin Clive-Smith, Edward Henry Reynolds
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Patent number: D877356Type: GrantFiled: March 9, 2018Date of Patent: March 3, 2020Assignee: Entia Ltd.Inventors: Millie Amy Catherine Clive-Smith, Toby Henry Basey-Fisher