Patents by Inventor Clive Booles

Clive Booles has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ANTI-MALARIAL PHARMACEUTICAL COMPOSITION
    Publication number: 20190290576
    Abstract: The invention provides pharmaceutical compositions for the treatment and prophylaxis of malaria, comprising artemether and a medium chain triglyceride formulated for transmucosal sublingual, buccal or nasal delivery, especially by a spray. Also provided are delivery devices containing the compositions.
    Type: Application
    Filed: June 3, 2019
    Publication date: September 26, 2019
    Applicant: Protopharma Limited
    Inventors: Clive Booles, Calvin Ross, Martin Sams
  • ANTI-MALARIAL PHARMACEUTICAL COMPOSITION
    Publication number: 20180071207
    Abstract: The invention provides pharmaceutical compositions for the treatment and prophylaxis of malaria, comprising artemether and a medium chain triglyceride formulated for transmucosal sublingual, buccal or nasal delivery, especially by a spray. Also provided are delivery devices containing the compositions.
    Type: Application
    Filed: November 20, 2017
    Publication date: March 15, 2018
    Applicant: Protopharma Limited
    Inventors: Clive Booles, Calvin Ross, Martin Sams
  • Sublingual administration of statins
    Patent number: 9849083
    Abstract: The invention provides a pharmaceutical composition for the transmucosal delivery of a statin, said composition comprising a statin and a carrier in which said statin is soluble or forms a suspension or emulsion. The invention also provides a pharmaceutical composition comprising a statin for use in inhibiting cholesterol synthesis in vivo, where in said use said composition is delivered by the transmucosal route.
    Type: Grant
    Filed: December 14, 2012
    Date of Patent: December 26, 2017
    Assignee: LondonPharma Ltd.
    Inventors: Martin James Sams, Juliet Victoria High, Paul Andrew Jamieson, Clive Booles
  • Anti-Malarial Pharmaceutical Composition
    Publication number: 20160038404
    Abstract: The invention provides pharmaceutical compositions for the treatment and prophylaxis of malaria, comprising artemether and a medium chain triglyceride formulated for transmucosal sublingual, buccal or nasal delivery, especially by a spray. Also provided are delivery devices containing the compositions.
    Type: Application
    Filed: July 24, 2015
    Publication date: February 11, 2016
    Applicant: Protopharma Limited
    Inventors: Clive Booles, Calvin Ross, Martin Sams
  • Sublingual Administration of Statins
    Publication number: 20150328142
    Abstract: The invention provides a pharmaceutical composition for the transmucosal delivery of a statin, said composition comprising a statin and a carrier in which said statin is soluble or forms a suspension or emulsion. The invention also provides a pharmaceutical composition comprising a statin for use in inhibiting cholesterol synthesis in vivo, where in said use said composition is delivered by the transmucosal route.
    Type: Application
    Filed: December 14, 2012
    Publication date: November 19, 2015
    Applicant: LondonPharma Ltd.
    Inventors: Martin James Sams, Juliet Victoria High, Paul Andrew Jamieson, Clive Booles
  • Drug Delivery Technology
    Publication number: 20150005307
    Abstract: The invention provides a pharmaceutical composition for the transmucosal delivery of a PDE5 inhibitor, said composition comprising a PDE5 inhibitor and a carrier in which said PDE5 inhibitor is soluble or forms a suspension or emulsion. The invention also provides a pharmaceutical composition comprising a PDE5 inhibitor for use in inhibiting PDE activity in vivo, where in said use said composition is delivered by the transmucosal route.
    Type: Application
    Filed: December 19, 2012
    Publication date: January 1, 2015
    Applicant: LondonPharma Ltd.
    Inventors: Martin James Sams, Juliet Victoria High, Paul Andrew Jamieson, Clive Booles
  • Anti-Malarial Pharmaceutical Composition
    Publication number: 20140179772
    Abstract: The invention provides pharmaceutical compositions for the treatment and prophylaxis of malaria, comprising artemether and a medium chain triglyceride formulated for transmucosal sublingual, buccal or nasal delivery, especially by a spray. Also provided are delivery devices containing the compositions.
    Type: Application
    Filed: July 26, 2013
    Publication date: June 26, 2014
    Applicant: Protopharma Limited
    Inventors: Clive Booles, Calvin Ross, Martin Sams
  • Sublingual Pharmaceutical Composition Comprising a Neutral Oil
    Publication number: 20120058158
    Abstract: The invention provides pharmaceutical compositions for the sublingual delivery of medicaments comprising a neutral oil and a medicament soluble in said oil, providing that said medicament is not nitroglycerine. The invention also provides delivery devices adapted for sublingual delivery of such compositions.
    Type: Application
    Filed: April 23, 2010
    Publication date: March 8, 2012
    Applicant: LONDONPHARMA LTD.
    Inventor: Clive Booles
  • ANTI-MALARIAL PHARMACEUTICAL COMPOSITION
    Publication number: 20110015260
    Abstract: The invention provides pharmaceutical compositions for the treatment and prophylaxis of malaria, comprising artemether and a medium chain triglyceride formulated for transmucosal sublingual, buccal or nasal delivery, especially by a spray. Also provided are delivery devices containing the compositions.
    Type: Application
    Filed: October 27, 2008
    Publication date: January 20, 2011
    Applicant: PROTOPHARMA LIMITED
    Inventors: Clive Booles, Calvin Ross, Martin Sams
  • Novel compositions and formulations
    Publication number: 20090270438
    Abstract: There is provided according to the invention a non-pressurised pharmaceutical liquid solution spray composition comprising: (i) buprenorphine; and a solvent comprising ethanol which composition is substantially free of chloride. There is also provided according to the invention a non-pressurised pharmaceutical liquid solution spray formulation comprising: (i) buprenorphine; (ii) a solvent comprising ethanol; and (iii) one or more antioxidants each of a molar ratio of antioxidant:buprenorphine between 0.2:1 and 25:1.
    Type: Application
    Filed: April 17, 2009
    Publication date: October 29, 2009
    Inventors: Clive Booles, Padriac O'Brien, David Antony Phillip Small, Matthew John Tyler
  • Novel compositions
    Publication number: 20060062812
    Abstract: Compositions and method are provided, for the treatment of pain, e.g. acute breakthrough pain, by means of a systemic, non-invasive mode of administration. Specifically, the invention relates to a sublingual presentation of an opioid analgesic, such as fentanyl, or its salts, in amounts that are sufficient to treat the pain.
    Type: Application
    Filed: September 12, 2005
    Publication date: March 23, 2006
    Inventors: Calvin Ross, Clive Booles, Alistair Campbell, Paul Woodcock, Scott Davis
  • Pressurized solvent-free drug aerosol compositions containing hydrofluorocarbon propellants
    Patent number: 5846521
    Abstract: Pressurised aerosol compositions comprise a medicament, a hydrofluorocarbon propellant and a polyethoxylated surfactant, the compositions containing substantially no solvent, other than the propellant, capable of increasing the solubility of the surfactant in the propellant. The compositions according to the invention are advantageous in that the solubility of the surfactant is such as to ensure good dispersion of the medicament and smooth operation of the aerosol valve.
    Type: Grant
    Filed: July 14, 1997
    Date of Patent: December 8, 1998
    Assignee: Fisons plc
    Inventors: Asit Somani, Clive Booles