Patents by Inventor Clive Griffiths
Clive Griffiths has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 12203060Abstract: Aspects of the present invention relate to apparatus for use in cell and tissue culture techniques. Particularly, although not exclusively, embodiments of the present invention relate to apparatus which contribute to providing a dynamic cell culture environment. Also disclosed herein are methods for culturing cells and/or tissues, together with in vitro methods of testing drug efficacy as well as other subject matter.Type: GrantFiled: December 30, 2023Date of Patent: January 21, 2025Assignee: FIBROFIND IP LIMITEDInventors: Fiona Oakley, Lee Borthwick, Clive Griffiths, Michael Drinnan
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Patent number: 12049611Abstract: Aspects of the present invention relate to apparatus for use in cell and tissue culture techniques. Particularly, although not exclusively, embodiments of the present invention relate to apparatus which contribute to providing a dynamic cell culture environment. Also disclosed herein are methods for culturing cells and/or tissues, together with in vitro methods of testing drug efficacy as well as other subject matter.Type: GrantFiled: October 21, 2016Date of Patent: July 30, 2024Assignee: FIBROFIND IP LIMITEDInventors: Fiona Oakley, Lee Borthwick, Clive Griffiths, Michael Drinnan
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Patent number: 10682454Abstract: An apparatus for performing haemodialysis on a patient comprises: first blood transfer means (3) for selectively withdrawing blood from a patient and storing it in a first storage portion (5); second blood transfer means (11) for removing filtered blood from a filtration device (7) and storing it in a second storage portion (13); and a fluid measurement system (51a, 51b) for periodically measuring the respective volumes of blood in the first and second storage portions; adding the volume of blood in the first storage portion to the volume of blood in the second storage portion at that time in order to calculate the total volume of blood within the first and second storage portions at that time; and comparing the total measured volumes of blood within the first and second storage portions measured over a predetermined time interval to calculate the volume of fluid removed from the blood during that predetermined time interval.Type: GrantFiled: June 14, 2012Date of Patent: June 16, 2020Assignee: The Newcastle Upon Tyne Hospitals NHS Foundation TrustInventors: Malcolm Coulthard, Michael Whitaker, Clive Griffiths, Michael Drinnan
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Publication number: 20190002809Abstract: Aspects of the present invention relate to apparatus for use in cell and tissue culture techniques. Particularly, although not exclusively, embodiments of the present invention relate to apparatus which contribute to providing a dynamic cell culture environment. Also disclosed herein are methods for culturing cells and/or tissues, together with in vitro methods of testing drug efficacy as well as other subject matter.Type: ApplicationFiled: October 21, 2016Publication date: January 3, 2019Applicant: University of Newcastle Upon TyneInventors: Fiona OAKLEY, Lee BORTHWICK, Clive GRIFFITHS, Michael DRINNAN
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Publication number: 20180103856Abstract: A blood pressure measurement system is able to measure actual blood pressures. More specifically, the blood pressure sensor or sphygmomanometer is able to detect high frequencies that exist only between systole and diastole, and thus identify aspects such as micro-pulses associated with the opening and closing of an artery to achieve accurate blood pressure readings.Type: ApplicationFiled: April 15, 2016Publication date: April 19, 2018Inventors: Alan MURRAY, Dingchang ZHENG, Clive GRIFFITHS, Chengyu LIU
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Publication number: 20140296746Abstract: A urine flow measuring apparatus that includes a container for receiving urine, measuring means for measuring the weight and/or volume of urine received by the container, and memory means for recording the weight and/or volume measured by the measuring means. Through a controller the measuring means: continually measures the weight and/or volume of the container at regular sampling intervals; and at each sampling interval, identifies if a positive change in the weight and/or volume of the container has occurred and then compares results within a data set, the data set including a result from the current sampling interval and results from all the sampling intervals during a given period. If a number of sampling intervals indicating a positive change in the weight and/or volume is above a certain threshold, the memory means is instructed to begin recording data, else the memory means is instructed to cease recording data.Type: ApplicationFiled: August 9, 2012Publication date: October 2, 2014Applicant: Newcastle-upon-Tyne Hospitals NHS Foundation TrustInventors: Michael Whitaker, Michael Drinnan, Alison Bray, Clive Griffiths, Robert Beckwith
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Publication number: 20140110319Abstract: An apparatus for performing haemodialysis on a patient comprises: first blood transfer means (3) for selectively withdrawing blood from a patient and storing it in a first storage portion (5); second blood transfer means (11) for removing filtered blood from a filtration device (7) and storing it in a second storage portion (13); and a fluid measurement system (51a, 51b) for periodically measuring the respective volumes of blood in the first and second storage portions; adding the volume of blood in the first storage portion to the volume of blood in the second storage portion at that time in order to calculate the total volume of blood within the first and second storage portions at that time; and comparing the total measured volumes of blood within the first and second storage portions measured over a predetermined time interval to calculate the volume of fluid removed from the blood during that predetermined time interval.Type: ApplicationFiled: June 14, 2012Publication date: April 24, 2014Applicant: THE NEWCASTLE UPON TYNE HOSPITALS NHS FOUNDATION TRUSTInventors: Malcolm Coulthard, Michael Whitaker, Clive Griffiths, Michael Drinnan
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Patent number: 8620412Abstract: An apparatus that is able to detect the position of a catheter. The apparatus utilizes a catheter filled with electrically-conductive physiological saline and a connector for establishing an electrical connection between the saline of the catheter and an input of a controller. The controller includes at least one output connectable to a standard ECG lead connector, wherein the controller includes circuitry for generating a low impedance output signal. The controller provides an output which replicates the input a standard ECG patient lead connector is configured to receive. The apparatus provides a more convenient and cost effective solution for providing specialized ECG functions without having to replace a hospital's existing ECG beside monitoring equipment.Type: GrantFiled: April 23, 2008Date of Patent: December 31, 2013Assignee: The Newcastle Upon Tyne Hospitals NHS TrustInventors: Clive Griffiths, Mike Whitaker
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Publication number: 20100292764Abstract: A device (100) and method for achieving localised hypothermia during laparoscopic surgery comprises a sheath portion (101) in the form of a flexible bag-like shape which is shaped and sized so that it substantially surrounds the organ of interest in use. The sheath portion (101) comprises walls, each consisting of at least a first inner layer and a second outer layer which define a space therebetween into which catheters (104a, b) deliver and remove cooled fluid to provide a cooling effect to the organ.Type: ApplicationFiled: April 26, 2007Publication date: November 18, 2010Applicant: The Newcastle Upon Tyne Hospitals NHS TrustInventors: Naeem Soomro, Clive Griffiths, Elaine Colechin, John Riddle
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Publication number: 20100152596Abstract: Apparatus for Detecting the Position of a Catheter Apparatus for detecting the position of a catheter comprising a catheter, electrically conductive means associated with the catheter, a connector for establishing an electrical connection between the electrically conductive means associated with the catheter and an output of the connector and a controller having at least one output connectable to an ECG patient connector, wherein the controller includes at least one input and the said at least one input includes an electrical connection from the controller to the output of the connector and wherein the controller includes means for generating a low impedance output signal.Type: ApplicationFiled: April 23, 2008Publication date: June 17, 2010Applicant: THE NEWCASTLE UPON TYNE HOSPITALS NHS TRUSTInventors: Clive Griffiths, Mike Whitaker
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Patent number: 7381854Abstract: A process for the selective hydrogenation of alpha-methyl-styrene (AMS) to cumene in a two catalyst system is disclosed. A crude cumene feed stream containing up to 10% AMS by weight is supplied to the first reaction zone 112 and mixed with hydrogen in a first catalyst bed 118 containing a nickel catalyst, converting from 70 to 95 percent of the AMS to cumene. Cumene and remaining AMS are separated from hydrogen in a liquid take off tray 120. The first reaction zone 112 effluent is supplied to a second reaction zone 114, where the effluent and hydrogen gas are mixed in a second catalyst bed 126 containing a noble-metal catalyst to substantially convert any remaining AMS to cumene. Cumene is collected, separated from the hydrogen, and can be resupplied to the hydrogenation reactor 110, or supplied as feed to a phenol synthesis loop.Type: GrantFiled: December 20, 2004Date of Patent: June 3, 2008Assignee: Kellogg Brown & Root LLCInventors: Ronald Birkhoff, Clive Griffiths, Kiran Shah, Anand Subramanian
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Publication number: 20060135830Abstract: A process for the selective hydrogenation of alpha-methyl-styrene (AMS) to cumene in a two catalyst system is disclosed. A crude cumene feed stream containing up to 10% AMS by weight is supplied to the first reaction zone 112 and mixed with hydrogen in a first catalyst bed 118 containing a nickel catalyst, converting from 70 to 95 percent of the AMS to cumene. Cumene and remaining AMS are separated from hydrogen in a liquid take off tray 120. The first reaction zone 112 5effluent is supplied to a second reaction zone 114, where the effluent and hydrogen gas are mixed in a second catalyst bed 126 containing a noble-metal catalyst to substantially convert any remaining AMS to cumene. Cumene is collected, separated from the hydrogen, and can be resupplied to the hydrogenation reactor 110, or supplied as feed to a phenol synthesis loop.Type: ApplicationFiled: December 20, 2004Publication date: June 22, 2006Applicant: KELLOGG BROWN AND ROOT, INC.Inventors: Ronald Birkhoff, Clive Griffiths, Kiran Shah, Anand Subramanian