Abstract: Disclosed is a headphone audio cable connection structure, including a headphone body and an audio cable, where the headphone body is provided with an audio cable insertion hole and a clamping sleeve, the audio cable extends into the clamping sleeve and is inserted into the audio cable insertion hole, inserting grooves and clamping grooves are formed on a side wall of the clamping sleeve, the audio cable is sleeved with a clamping seat, and protruding clamping blocks are arranged on the clamping seat. The present disclosure ensures a stable connection of the audio cable, prevents the audio cable from falling off, and facilitates replacement of the audio cable.