Patents by Inventor Clovis Rakotoarivelo

Clovis Rakotoarivelo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11484571
    Abstract: A pharmaceutical product containing ?2-microglobulin or a functional variant thereof as an active ingredient in the form of liposomes is provided. The product can increase the concentration of ?2-microglobulin in the blood, and can also restore a normal HC/?2-microglobulin molar ratio within membrane MHC-I complexes, or prevent a ?2-microglobulin deficit from occurring in the MHC-I complexes, of patients suffering from autoimmune diseases. Methods of treating patients with the pharmaceutical product are also presented.
    Type: Grant
    Filed: October 20, 2016
    Date of Patent: November 1, 2022
    Assignee: BETA INNOV
    Inventors: Marcel Mersel, Clovis Rakotoarivelo
  • Publication number: 20210283146
    Abstract: Disclosed is a composition including a 7?-hydroxycholesterol derivative and a lipid vehicle, in particular a vegetable oil, and use thereof in the treatment of neoplastic pathologies, such as glioblastoma multiforme. The composition may be administered by the oral route.
    Type: Application
    Filed: July 11, 2019
    Publication date: September 16, 2021
    Inventors: Marcel MERSEL, Clovis RAKOTOARIVELO
  • Publication number: 20170035846
    Abstract: A pharmaceutical product containing ?2-microglobulin or a functional variant thereof as an active ingredient in the form of liposomes is provided. The product can increase the concentration of ?2-microglobulin in the blood, and can also restore a normal HC/?2-microglobulin molar ratio within membrane MHC-I complexes, or prevent a ?2-microglobulin deficit from occurring in the MHC-I complexes, of patients suffering from autoimmune diseases. Methods of treating patients with the pharmaceutical product are also presented.
    Type: Application
    Filed: October 20, 2016
    Publication date: February 9, 2017
    Inventors: Marcel MERSEL, Clovis RAKOTOARIVELO
  • Publication number: 20130017212
    Abstract: The use of beta2-microglobulin (?2m) as active ingredient, in particular in pharmaceutical compositions intended for the treatment of autoimmune diseases.
    Type: Application
    Filed: April 6, 2011
    Publication date: January 17, 2013
    Applicant: BETA INNOV
    Inventors: Marcel Mersel, Clovis Rakotoarivelo