Patents by Inventor Coimbatore Nagaraja Sridhar

Coimbatore Nagaraja Sridhar has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Serially directed combinatorial synthesis on fiber optic arrays
    Patent number: 6156494
    Abstract: A method has been developed which utilizes functionalized optical fibers as a solid support for the assembly of combinatorial libraries of compounds. The optical fibers are used to direct light, heat or a combination thereof to the compounds tethered to the fibers surface. Utilizing the method of the instant invention reactions occurring by both photochemically and thermally allowed pathways are accessible. In a preferred embodiment of the invention, the optical fibers are used to screen the array by fluorescence spectroscopy of labeled target molecules which bind to the immobilized library compounds.
    Type: Grant
    Filed: October 28, 1997
    Date of Patent: December 5, 2000
    Assignee: Mosaic Technologies
    Inventors: Christopher Adams, T. Christian Boles, Coimbatore Nagaraja Sridhar