Patents by Inventor Cole Seifert

Cole Seifert has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Synthesis strategy for gap protecting group
    Patent number: 11827660
    Abstract: The present invention relates to a novel synthesis method to form particular molecules. These molecules have multiple uses, most notably in the field of protecting groups used throughout organic and synthetic chemistry. The disclosed method is safer, more cost- and time-effective, and more amenable to large scale production than those currently known in the art. The protecting groups synthesized are useful in GAP peptide synthesis.
    Type: Grant
    Filed: January 26, 2020
    Date of Patent: November 28, 2023
    Assignee: Sederma
    Inventor: Cole Seifert
  • SYNTHESIS STRATEGY FOR GAP PROTECTING GROUP
    Publication number: 20220089619
    Abstract: The present invention relates to a novel synthesis method to form particular molecules. These molecules have multiple uses, most notably in the field of protecting groups used throughout organic and synthetic chemistry. The disclosed method is safer, more cost- and time-effective, and more amenable to large scale production than those currently known in the art. The protecting groups synthesized are useful in GAP peptide synthesis.
    Type: Application
    Filed: January 26, 2020
    Publication date: March 24, 2022
    Applicant: GAP Peptides, LLC
    Inventor: Cole Seifert
  • SYSTEM AND METHOD FOR SOLUTION PHASE GAP PEPTIDE SYNTHESIS
    Publication number: 20210171569
    Abstract: Disclosed is a system and method for Fmoc/tBu solution-phase peptide synthesis including the development of a new benzyl-type GAP protecting group, and related uses thereto. This novel GAP protecting group is utilized in place of a polymer support, facilitating C to N Fmoc peptide synthesis without chromatography, recrystallization, or polymer supports. The GAP group can be added and removed in high yield.
    Type: Application
    Filed: February 10, 2021
    Publication date: June 10, 2021
    Inventors: Guigen Li, Cole Seifert
  • COMPOSITIONS AND METHODS FOR CHEMICAL SYNTHESIS
    Publication number: 20210079036
    Abstract: The disclosure relates to chemical compositions that can include anchor molecules for chemical synthesis. GAP anchor molecules can include GAP constituents, linker constituents, and spacer constituents. Anchor molecules can be used to synthetically manufacture peptides. A novel method of solution-phase peptide synthesis is also disclosed that utilizes novel group-assisted purification protecting groups to facilitate efficient, scalable chemistry to synthetically manufacture peptides.
    Type: Application
    Filed: November 25, 2020
    Publication date: March 18, 2021
    Applicant: GAP Peptides LLC
    Inventor: Cole Seifert
  • System and method for solution phase gap peptide synthesis
    Patent number: 10947267
    Abstract: Disclosed is a system and method for Fmoc/tBu solution-phase peptide synthesis including the development of a new benzyl-type GAP protecting group, and related uses thereto. This novel GAP protecting group is utilized in place of a polymer support, facilitating C to N Fmoc peptide synthesis without chromatography, recrystallization, or polymer supports. The GAP group can be added and removed in high yield.
    Type: Grant
    Filed: December 21, 2016
    Date of Patent: March 16, 2021
    Assignee: Texas Tech University System
    Inventors: Guigen Li, Cole Seifert
  • SYSTEM AND METHOD FOR SOLUTION PHASE GAP PEPTIDE SYNTHESIS
    Publication number: 20190330262
    Abstract: Disclosed is a system and method for Fmoc/tBu solution-phase peptide synthesis including the development of a new benzyl-type GAP protecting group, and related uses thereto. This novel GAP protecting group is utilized in place of a polymer support, facilitating C to N Fmoc peptide synthesis without chromatography, recrystallization, or polymer supports. The GAP group can be added and removed in high yield.
    Type: Application
    Filed: December 21, 2016
    Publication date: October 31, 2019
    Inventors: Guigen Li, Cole Seifert