Patents by Inventor Cole Seifert

Cole Seifert has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12344632
    Abstract: Disclosed is a system and method for Fmoc/tBu solution-phase peptide synthesis including the development of a new benzyl-type GAP protecting group, and related uses thereto. This novel GAP protecting group is utilized in place of a polymer support, facilitating C to N Fmoc peptide synthesis without chromatography, recrystallization, or polymer supports. The GAP group can be added and removed in high yield.
    Type: Grant
    Filed: February 10, 2021
    Date of Patent: July 1, 2025
    Assignee: Texas Tech University System
    Inventors: Guigen Li, Cole Seifert
  • Publication number: 20240391949
    Abstract: The disclosure relates to chemical compositions that can include anchor molecules for chemical synthesis. GAP anchor molecules can include GAP constituents, linker constituents, and spacer constituents. Anchor molecules can be used to synthetically manufacture peptides. A novel method of solution-phase peptide synthesis is also disclosed that utilizes novel group-assisted purification protecting groups to facilitate efficient, scalable chemistry to synthetically manufacture peptides.
    Type: Application
    Filed: May 17, 2024
    Publication date: November 28, 2024
    Applicant: Sederma
    Inventor: Cole Seifert
  • Publication number: 20240217995
    Abstract: The disclosure relates to compositions that can serve as anchors for the chemical synthesis of peptides. Anchor molecules can include GAP constituents, linker constituents, amino acid constituents, and/or stopper constituents. Anchor molecules can also include anchor peptides, wherein an anchor peptide can be removably coupled with an amino acid of a given sequence and act as a GAP anchor by achieving solubility control over the target peptide as it is synthesized via the addition of one or more other amino acids: the anchor peptide can then be removed from the target peptide. A novel method of peptide synthesis that utilizes novel anchor molecules and/or anchor peptides is also presented.
    Type: Application
    Filed: April 22, 2022
    Publication date: July 4, 2024
    Applicant: Sederma
    Inventor: Cole Seifert
  • Patent number: 12024537
    Abstract: The disclosure relates to chemical compositions that can include anchor molecules for chemical synthesis. GAP anchor molecules can include GAP constituents, linker constituents, and spacer constituents. Anchor molecules can be used to synthetically manufacture peptides. A novel method of solution-phase peptide synthesis is also disclosed that utilizes novel group-assisted purification protecting groups to facilitate efficient, scalable chemistry to synthetically manufacture peptides.
    Type: Grant
    Filed: November 25, 2020
    Date of Patent: July 2, 2024
    Assignee: Sederma
    Inventor: Cole Seifert
  • Patent number: 11827660
    Abstract: The present invention relates to a novel synthesis method to form particular molecules. These molecules have multiple uses, most notably in the field of protecting groups used throughout organic and synthetic chemistry. The disclosed method is safer, more cost- and time-effective, and more amenable to large scale production than those currently known in the art. The protecting groups synthesized are useful in GAP peptide synthesis.
    Type: Grant
    Filed: January 26, 2020
    Date of Patent: November 28, 2023
    Assignee: Sederma
    Inventor: Cole Seifert
  • Publication number: 20220089619
    Abstract: The present invention relates to a novel synthesis method to form particular molecules. These molecules have multiple uses, most notably in the field of protecting groups used throughout organic and synthetic chemistry. The disclosed method is safer, more cost- and time-effective, and more amenable to large scale production than those currently known in the art. The protecting groups synthesized are useful in GAP peptide synthesis.
    Type: Application
    Filed: January 26, 2020
    Publication date: March 24, 2022
    Applicant: GAP Peptides, LLC
    Inventor: Cole Seifert
  • Publication number: 20210171569
    Abstract: Disclosed is a system and method for Fmoc/tBu solution-phase peptide synthesis including the development of a new benzyl-type GAP protecting group, and related uses thereto. This novel GAP protecting group is utilized in place of a polymer support, facilitating C to N Fmoc peptide synthesis without chromatography, recrystallization, or polymer supports. The GAP group can be added and removed in high yield.
    Type: Application
    Filed: February 10, 2021
    Publication date: June 10, 2021
    Inventors: Guigen Li, Cole Seifert
  • Publication number: 20210079036
    Abstract: The disclosure relates to chemical compositions that can include anchor molecules for chemical synthesis. GAP anchor molecules can include GAP constituents, linker constituents, and spacer constituents. Anchor molecules can be used to synthetically manufacture peptides. A novel method of solution-phase peptide synthesis is also disclosed that utilizes novel group-assisted purification protecting groups to facilitate efficient, scalable chemistry to synthetically manufacture peptides.
    Type: Application
    Filed: November 25, 2020
    Publication date: March 18, 2021
    Applicant: GAP Peptides LLC
    Inventor: Cole Seifert
  • Patent number: 10947267
    Abstract: Disclosed is a system and method for Fmoc/tBu solution-phase peptide synthesis including the development of a new benzyl-type GAP protecting group, and related uses thereto. This novel GAP protecting group is utilized in place of a polymer support, facilitating C to N Fmoc peptide synthesis without chromatography, recrystallization, or polymer supports. The GAP group can be added and removed in high yield.
    Type: Grant
    Filed: December 21, 2016
    Date of Patent: March 16, 2021
    Assignee: Texas Tech University System
    Inventors: Guigen Li, Cole Seifert
  • Publication number: 20190330262
    Abstract: Disclosed is a system and method for Fmoc/tBu solution-phase peptide synthesis including the development of a new benzyl-type GAP protecting group, and related uses thereto. This novel GAP protecting group is utilized in place of a polymer support, facilitating C to N Fmoc peptide synthesis without chromatography, recrystallization, or polymer supports. The GAP group can be added and removed in high yield.
    Type: Application
    Filed: December 21, 2016
    Publication date: October 31, 2019
    Inventors: Guigen Li, Cole Seifert