Patents by Inventor Colette A. Douzon

Colette A. Douzon has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5019269
    Abstract: These resins derived from a crosslinked styrene (co)-polymer, or from a crosslinked dextran, comprise a (co)-polymer chain which is substituted with one or more groups, which may be identical or different, belonging to the following categories: --Z--A.sub.1 ; --Z--A.sub.2 ; --Z--A.sub.1 --Z'--A.sub.2 ; --Z--A.sub.1 --A.sub.3 --A.sub.2 ; --Z--A.sub.1 --A.sub.4, where Z=spacer chain, Z'=linking chain, A.sub.1 =phosphate residue, A.sub.2 =residue of purine or pyrimidine base, A.sub.3 =sugar residue and A.sub.4 =residue of a molecule participating in the polar structure of various phospholipids. These resins are applicable for the analysis and purification of molecules of biological origin, in particular as a stationary phase in ion-exchange and affinity chromatography, especially for carrying out the fractionation of protein mixtures.
    Type: Grant
    Filed: March 21, 1990
    Date of Patent: May 28, 1991
    Assignee: Centre National de la Recherche Scientifique
    Inventors: Didier Letourneur, Colette Douzon, Veronique Migonney, Daniel A. Muller, Marcel Jozefowicz
  • Patent number: 4950712
    Abstract: These resins derived from a crosslinked styrene (co)-polymer, or from a crosslinked dextran, comprise a (co)-polymer chain which is substituted with one or more groups, which may be identical or different, belonging to the following categories: --Z--A.sub.1 ; --Z--A.sub.2 ; --Z--A.sub.1 --Z'--A.sub.2 ; --Z--A.sub.1 --A.sub.3 --A.sub.2 ; --Z--A.sub.1 --A.sub.4, where Z=spacer chain, Z'=linking chain, A.sub.1 =phosphate residue, A.sub.2 =residue of purine or pyrimidine base, A.sub.3 =sugar residue and A.sub.4 =residue of a molecule participating in the polar structure of various phospholipids. These resins are applicable for the analysis and purification of molecules of biological origin, in particular as a stationary phase in ion-exchange and affinity chromatography, especially for carrying out the fractionation of protein mixtures.
    Type: Grant
    Filed: August 22, 1988
    Date of Patent: August 21, 1990
    Assignee: Centre National de la Recherche Scientifique (C.N.R.S.)
    Inventors: Didier Letourneur, Colette Douzon, Veronique Migonney, Daniel A. Muller, Marcel Jozefowicz
  • Patent number: 4526786
    Abstract: N-aryl oxazolidinones, oxazolidinethiones, pyrrolidinones, pyrrolidines and thiazolidinones are disclosed. These compounds possess antidepressant activity.
    Type: Grant
    Filed: June 16, 1982
    Date of Patent: July 2, 1985
    Assignee: Delalande S.A.
    Inventors: Guy R. Bourgery, Colette A. Douzon, Jean-Francois R. Ancher, Alain P. Lacour, Patrick G. Guerret, Michel Langlois, Phillippe L. Dostert
  • Patent number: 4517197
    Abstract: A compound of the formula ##STR1## where R is selected from the group consisting of CH.sub.3 --CO--(CH.sub.2).sub.2 --O--, ##STR2## The compounds are useful in treating depression.
    Type: Grant
    Filed: July 29, 1983
    Date of Patent: May 14, 1985
    Assignee: Delalande S.A.
    Inventors: Jean-Francois R. Ancher, Guy R. Bourgery, Philippe L. Dostert, Colette A. Douzon, Patrick G. Guerret, Alain P. Lacour, Michel Langlois
  • Patent number: 4470993
    Abstract: Method of treating the central nervous system troubles such as the Parkinson's disease and the senescence troubles, generally treated by the B type monoamine oxidase inhibitors, which comprises administering internally to a human being requiring such treatment a therapeutically effective amount of N-aryl 5-aminomethyl oxazolidine-2-one derivatives.
    Type: Grant
    Filed: March 3, 1983
    Date of Patent: September 11, 1984
    Assignee: Delalande S.A.
    Inventors: Jean-Francois R. Ancher, Guy R. Bourgery, Philippe L. Dostert, Colette A. Douzon, Patrick G. Guerret, Alain P. Lacour, Michel Langlois, Margherita Strolin-Benedetti
  • Patent number: 4435415
    Abstract: N-aryl oxazolidinones, oxazolidinethiones, pyrrolidinones, pyrrolidines and thiazolidinones are disclosed. These compounds possess antidepressant activity.
    Type: Grant
    Filed: June 16, 1982
    Date of Patent: March 6, 1984
    Assignee: Delalande S.A.
    Inventors: Guy R. Bourgery, Colette A. Douzon, Jean-Francois R. Ancher, Alain P. Lacour, Patrick G. Guerret, Michel Langlois, Philippe L. Dostert
  • Patent number: 4413001
    Abstract: N-aryl oxazolidinones, oxazolidinethiones, pyrrolidinones, pyrrolidines and thiazolidinones are disclosed. These compounds possess antidepressant activity.
    Type: Grant
    Filed: June 16, 1982
    Date of Patent: November 1, 1983
    Assignee: Delalande S.A.
    Inventors: Guy R. Bourgery, Colette A. Douzon, Jean-Francois R. Ancher, Alain P. Lacour, Patrick G. Guerret, Michel Langlois, Philippe L. Dostert
  • Patent number: 4348393
    Abstract: N-aryl oxazolidinones, oxazolidinethiones, pyrrolidinones, pyrrolidines and thiazolidinones are disclosed. These compounds possess antidepressant activity.
    Type: Grant
    Filed: June 4, 1979
    Date of Patent: September 7, 1982
    Assignee: Delalande S.A.
    Inventors: Guy R. Bourgery, Colette A. Douzon, Jean-Francois R. Ancher, Alain P. Lacour, Patrick G. Guerret, Michel Langlois, Phillippe L. Dostert
  • Patent number: 4338451
    Abstract: There are disclosed 3-substituted phenyl-5-hydroxymethyl oxazolidinones which possess anti-depressant properties. The compounds are prepared by cyclizing, with ethyl carbonate, 1-substituted phenylamino-2,3-propanediol compounds.
    Type: Grant
    Filed: August 1, 1980
    Date of Patent: July 6, 1982
    Assignee: Delalande S.A.
    Inventors: Philippe L. Dostert, Colette A. Douzon, Guy R. Bourgery, Claude G. Gouret, Gisele C. Mocquet, Jean A. Coston
  • Patent number: 4287351
    Abstract: N-aryl oxazolidinones, oxazolidinethiones, pyrrolidinones, pyrrolidines and thiazolidinones are disclosed. These compounds possess antidepressant activity.
    Type: Grant
    Filed: February 6, 1980
    Date of Patent: September 1, 1981
    Assignee: Delalande S.A.
    Inventors: Guy R. Bourgery, Colette A. Douzon, Jean-Francois R. Ancher, Alain P. Lacour, Patrick G. Guerret, Michel Langlois, Phillippe L. Dostert
  • Patent number: 4250318
    Abstract: There are disclosed 3-substituted phenyl-5-hydroxymethyl oxazolidinones which possess anti-depressant properties. The compounds are prepared by cyclizing, with ethyl carbonate, 1-substituted phenylamino-2,3-propanediol compounds.
    Type: Grant
    Filed: August 9, 1978
    Date of Patent: February 10, 1981
    Assignee: Delalande S.A.
    Inventors: Philippe L. Dostert, Colette A. Douzon, Guy R. Bourgery, Claude G. Gouret, Gisele C. Mocquet, Jean-Alain Coston
  • Patent number: 4150029
    Abstract: Compounds having the formula ##STR1## wherein R.sub.1 is hydrogen or CONHR.sub.7 and R.sub.7 is methyl or isopropyl,And whereinWhen R.sub.1 is hydrogen: R is p-nitro, p-cyano; p-aldehydo; p-acetyl; m-ethyl; m-nitro; m-bromo; 3,4-dimethyl; m-NH.sub.2 ; p-methylamino; p-dimethylamino; p-diethylamino; p-methylbenzylamino; p-pyrrolidino; p-piperidino; SR.sub.4 in para position in which R.sub.4 is alkyl having 1 to 4 carbon atoms or cyclohexyl; OR.sub.5 is para position in which R.sub.5 is alkyl having 2 to 7 carbon atoms, cyclohexyl, cyclohexylmethyl, acetylmethyl; cyanomethyl, alkene-2 yl having 3 to 5 carbon atoms, butene-3 yl, cyclohexene-1 methyl, propargyl, butyne-2 yl, ##STR2## in which n is one or 2 and when n is one, R.sub.6 is hydrogen, o-fluoro, o-methyl, m-chloro, m-fluoro, m-methyl, m-trifluoromethyl, p-chloro, p-bromo-, p-fluoro, p-cyano, p-nitro or p-dimethylamino and when n is 2, R.sub.6 is hydrogen; and 3-methyl-4-benzyloxy:When R.sub.1 is CONHR.sub.7 and R.sub.
    Type: Grant
    Filed: February 23, 1977
    Date of Patent: April 17, 1979
    Assignee: Delalande S.A.
    Inventors: Philippe L. Dostert, Colette A. Douzon, Guy R. Bourgery, Claude J. Gouret, Gisele C. Mocquet, Jean A. Coston
  • Patent number: RE29607
    Abstract: Compounds of the formula ##STR1## in which R is H, .[.Cl, F, CH.sub.3 or CF.sub.3 .]. .Iadd.m-F, p-F, o-F, p-Cl, p-CH.sub.3, m-CH.sub.3 or m-CF.sub.3 .Iaddend.. The compounds are prepared by cyclizing with ethyl carbonate, a compound of the formula ##STR2## The compounds have anti-depressive, myorelaxing, tranquilizing, sedative, analgesic, anti-convulsive, anti-pyretic, anti-inflammatory and uricosuric activities.
    Type: Grant
    Filed: June 4, 1976
    Date of Patent: April 11, 1978
    Assignee: Delalande S. A.
    Inventors: Claude P. Fauran, Guy M. Raynaud, Rene A. Oliver, Colette A. Douzon
  • Patent number: RE29934
    Abstract: A compound of the formula ##STR1## .[.in which R is H, halogen, alkyl having 1 to 4 carbon atoms or trifluoromethyl, and R.sub.1 and R.sub.2 each is H or dialkylaminoalkyl or together with N comprise methylpiperazino..]. .Iadd.in which (1) .Iadd. ##STR2## .Iaddend. is -NH.sub.2 and R is H, m-CH.sub.3, o-CF.sub.3, m-Cl, p-Cl, m-Br, m-F, p-F, o-F, p-CH.sub.3 or m-CH.sub.3, or .Iadd. ##STR3## .Iaddend. and R is H, m-CF.sub.3 or m-F, or .Iadd. ##STR4## .Iaddend. and R is H, m-CF.sub.3 or m-F.The compound is prepared by treating the corresponding 5-hydroxymethyl compound with ammonia or an amine in the presence of phosgene.The compounds possess anti-depressive, myorelaxing, tranquilizing, sedative, analgesic, anti-convulsive, anti-pyretic, anti-inflammatory and uricosuric activities.
    Type: Grant
    Filed: March 3, 1976
    Date of Patent: March 13, 1979
    Assignee: Delalande S. A.
    Inventors: Claude P. Fauran, Guy M. Raynaud, Rene A. Oliver, Colette A. Douzon