Patents by Inventor Colette M. CUTLER

Colette M. CUTLER has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS OF SEPARATING HOST CELL LIPASES FROM AN ANTI-LAG3 ANTIBODY PRODUCTION
    Publication number: 20230077205
    Abstract: Provided herein are methods of separating host cell lipases from an anti-LAG3 antibody or antigen binding fragment in chromatographic processes and methods of improving polysorbate-80 stability in an anti-LAG3 antibody formulation by separating host cell lipases from the anti-LAG3 antibody or antigen binding fragment using chromatographic processes. Also provided are pharmaceutical compositions comprising an anti-LAG3 antibody or antigen binding fragment and less than 2 ppm of a host cell lipase.
    Type: Application
    Filed: January 28, 2021
    Publication date: March 9, 2023
    Applicant: Merck Sharp & Dohme LLC
    Inventors: Colette M. CUTLER, Hong LI, Sketa PATEL, Sandra E. RIOS, John P. WELSH