Patents by Inventor Colin A. Nyuli
Colin A. Nyuli has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 12138159Abstract: A prosthetic valve comprises a self-expanding frame which includes a self-expanding atrial skirt that forms a flanged region, a self-expanding ventricular skirt, and a first self-expanding tab coupled with the ventricular skirt. A receptacle for receiving a valve leaflet is formed by the area bounded by an outer surface of the atrial skirt, an outer surface of the ventricular skirt, and an inner surface of the first tab. The receptacle has a window for receiving the valve leaflet that is defined by a gap between an edge of the flange and a tip of the first tab. The gap is maximized when the tip of the first tab is unconstrained and a base of the first tab is at least partially constrained. The gap is minimized when the tip of the first tab and its base are unconstrained.Type: GrantFiled: October 13, 2022Date of Patent: November 12, 2024Assignee: Neovasc Tiara Inc.Inventors: Randy Matthew Lane, Colin A. Nyuli, Alexei J. Marko
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Patent number: 12109111Abstract: A delivery system includes a delivery catheter with a capsule configured to carry a prosthesis and a steering catheter for steering the delivery catheter. The delivery catheter can be advanced through a patient's vasculature to a target treatment area. The capsule can be opened and the prosthesis can be deployed into the target treatment area. Additionally, a method for delivering a prosthesis to a target treatment area includes advancing a delivery catheter through a patient's vasculature to the target treatment area, steering the delivery catheter toward the target treatment area, opening a capsule on the delivery catheter, and deploying the prosthesis into the target treatment area.Type: GrantFiled: March 9, 2020Date of Patent: October 8, 2024Assignee: Neovasc Tiara Inc.Inventors: Colin A. Nyuli, Randy Matthew Lane, Karen Tsoek-Ji Wong
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Patent number: 12053369Abstract: A sequentially deployed prosthetic cardiac valve includes a self-expanding frame having an atrial skirt, a ventricular skirt, and an annular region disposed therebetween. A first anterior tab is disposed on an anterior portion of the frame. A posterior tab is on a posterior portion of the self-expanding frame. The frame may be designed so that any portion may expand sequentially in any desired order. For example, a portion of the first anterior tab and a portion of the posterior tab may partially self-expand first. Next, the first anterior tab may fully self-expand before the posterior tab fully self-expands. The posterior tab may fully self-expand next followed by the ventricular skirt, or the ventricular skirt may self-expand next followed by full expansion of the posterior tab.Type: GrantFiled: July 8, 2022Date of Patent: August 6, 2024Assignee: Neovasc Tiara Inc.Inventors: Randy Matthew Lane, Colin A. Nyuli, Alexei J. Marko, Krista L. Neale
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Publication number: 20240122705Abstract: A prosthetic cardiac valve comprises an anchor having an atrial skirt, an annular region, and a ventricular skirt. The prosthetic valve also has a plurality of prosthetic valve leaflets each having a first end and a free end. The first end is coupled with the anchor and the free end is opposite the first end. The prosthetic cardiac valve has an open configuration in which the free ends of the prosthetic valve leaflets are disposed away from one another to allow antegrade blood flow therepast, and a closed configuration in which the free ends of the prosthetic valve leaflets engage one another and substantially prevent retrograde blood flow therepast. The anchor has a collapsed configuration for delivery to the heart and an expanded configuration for anchoring the prosthetic cardiac valve to a patient's heart.Type: ApplicationFiled: December 20, 2023Publication date: April 18, 2024Applicants: Neovasc Tiara Inc., Neovasc Inc.Inventors: Matthew Randy Lane, Colin A. Nyuli, Jeremy Brent Ratz, Arshad Quadri
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Patent number: 11793640Abstract: A sequentially deployed prosthetic cardiac valve includes a self-expanding frame having an atrial skirt, a ventricular skirt, and an annular region disposed therebetween. A first anterior tab is disposed on an anterior portion of the frame. A posterior tab is on a posterior portion of the self-expanding frame. The frame may be designed so that any portion may expand sequentially in any desired order. For example, a portion of the first anterior tab and a portion of the posterior tab may partially self-expand first. Next, the first anterior tab may fully self-expand before the posterior tab fully self-expands. The posterior tab may fully self-expand next followed by the ventricular skirt, or the ventricular skirt may self-expand next followed by full expansion of the posterior tab.Type: GrantFiled: October 21, 2020Date of Patent: October 24, 2023Assignee: Neovasc Tiara Inc.Inventors: Randy Matthew Lane, Colin A. Nyuli, Alexei J. Marko, Krista L. Neale
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Publication number: 20230149163Abstract: A prosthetic cardiac valve comprises an anchor having an atrial skirt, an annular region, and a ventricular skirt. The prosthetic valve also has a plurality of prosthetic valve leaflets each having a first end and a free end. The first end is coupled with the anchor and the free end is opposite the first end. The prosthetic cardiac valve has an open configuration in which the free ends of the prosthetic valve leaflets are disposed away from one another to allow antegrade blood flow therepast, and a closed configuration in which the free ends of the prosthetic valve leaflets engage one another and substantially prevent retrograde blood flow therepast. The anchor has a collapsed configuration for delivery to the heart and an expanded configuration for anchoring the prosthetic cardiac valve to a patient's heart.Type: ApplicationFiled: July 21, 2022Publication date: May 18, 2023Inventors: Randy Matthew Lane, Colin A. Nyuli
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Patent number: 11617650Abstract: A device for loading a prosthesis onto a delivery system includes a first housing having a central bore. One or more actuators on the first housing may be actuated radially inward to selectively compress a discrete portion of the prosthesis disposed in the central bore.Type: GrantFiled: June 16, 2022Date of Patent: April 4, 2023Assignee: Neovasc Tiara Inc.Inventors: Colin A. Nyuli, Randy Matthew Lane
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Publication number: 20230036649Abstract: A prosthetic valve comprises a self-expanding frame which includes a self-expanding atrial skirt that forms a flanged region, a self-expanding ventricular skirt, and a first self-expanding tab coupled with the ventricular skirt. A receptacle for receiving a valve leaflet is formed by the area bounded by an outer surface of the atrial skirt, an outer surface of the ventricular skirt, and an inner surface of the first tab. The receptacle has a window for receiving the valve leaflet that is defined by a gap between an edge of the flange and a tip of the first tab. The gap is maximized when the tip of the first tab is unconstrained and a base of the first tab is at least partially constrained. The gap is minimized when the tip of the first tab and its base are unconstrained.Type: ApplicationFiled: October 13, 2022Publication date: February 2, 2023Inventors: Randy Matthew Lane, Colin A. Nyuli, Alexei J. Marko
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Patent number: 11497602Abstract: A prosthetic valve comprises a self-expanding frame which includes a self-expanding atrial skirt that forms a flanged region, a self-expanding ventricular skirt, and a first self-expanding tab coupled with the ventricular skirt. A receptacle for receiving a valve leaflet is formed by the area bounded by an outer surface of the atrial skirt, an outer surface of the ventricular skirt, and an inner surface of the first tab. The receptacle has a window for receiving the valve leaflet that is defined by a gap between an edge of the flange and a tip of the first tab. The gap is maximized when the tip of the first tab is unconstrained and a base of the first tab is at least partially constrained. The gap is minimized when the tip of the first tab and its base are unconstrained.Type: GrantFiled: June 12, 2019Date of Patent: November 15, 2022Assignee: Neovasc Tiara Inc.Inventors: Randy Matthew Lane, Colin A. Nyuli, Alexei J. Marko
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Publication number: 20220338977Abstract: A sequentially deployed prosthetic cardiac valve includes a self-expanding frame having an atrial skirt, a ventricular skirt, and an annular region disposed therebetween. A first anterior tab is disposed on an anterior portion of the frame. A posterior tab is on a posterior portion of the self-expanding frame. The frame may be designed so that any portion may expand sequentially in any desired order. For example, a portion of the first anterior tab and a portion of the posterior tab may partially self-expand first. Next, the first anterior tab may fully self-expand before the posterior tab fully self-expands. The posterior tab may fully self-expand next followed by the ventricular skirt, or the ventricular skirt may self-expand next followed by full expansion of the posterior tab.Type: ApplicationFiled: July 8, 2022Publication date: October 27, 2022Inventors: Randy Matthew Lane, Colin A. Nyuli, Alexei J. Marko, Krista L. Neale
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Publication number: 20220313436Abstract: A device for loading a prosthesis onto a delivery system includes a first housing having a central bore. One or more actuators on the first housing may be actuated radially inward to selectively compress a discrete portion of the prosthesis disposed in the central bore.Type: ApplicationFiled: June 16, 2022Publication date: October 6, 2022Inventors: Colin A. Nyuli, Randy Matthew Lane
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Patent number: 11432924Abstract: A prosthetic cardiac valve comprises an anchor having an atrial skirt, an annular region, and a ventricular skirt. The prosthetic valve also has a plurality of prosthetic valve leaflets each having a first end and a free end. The first end is coupled with the anchor and the free end is opposite the first end. The prosthetic cardiac valve has an open configuration in which the free ends of the prosthetic valve leaflets are disposed away from one another to allow antegrade blood flow therepast, and a closed configuration in which the free ends of the prosthetic valve leaflets engage one another and substantially prevent retrograde blood flow therepast. The anchor has a collapsed configuration for delivery to the heart and an expanded configuration for anchoring the prosthetic cardiac valve to a patient's heart.Type: GrantFiled: October 21, 2019Date of Patent: September 6, 2022Assignees: Neovasc Tiara Inc., Edwards Lifesciences CardiAQ LLCInventors: Randy Matthew Lane, Colin A. Nyuli, Jeremy Brent Ratz, Arshad Quadri
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Patent number: 11419720Abstract: A prosthetic cardiac valve comprises an anchor having an atrial skirt, an annular region, and a ventricular skirt. The prosthetic valve also has a plurality of prosthetic valve leaflets each having a first end and a free end. The first end is coupled with the anchor and the free end is opposite the first end. The prosthetic cardiac valve has an open configuration in which the free ends of the prosthetic valve leaflets are disposed away from one another to allow antegrade blood flow therepast, and a closed configuration in which the free ends of the prosthetic valve leaflets engage one another and substantially prevent retrograde blood flow therepast. The anchor has a collapsed configuration for delivery to the heart and an expanded configuration for anchoring the prosthetic cardiac valve to a patient's heart.Type: GrantFiled: September 3, 2019Date of Patent: August 23, 2022Assignees: Neovasc Tiara Inc., Edwards Lifesciences CardiAQ LLCInventors: Randy Matthew Lane, Colin A. Nyuli, Jeremy Brent Ratz, Arshad Quadri
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Patent number: 11413139Abstract: A sequentially deployed prosthetic cardiac valve includes a self-expanding frame having an atrial skirt, a ventricular skirt, and an annular region disposed therebetween. A first anterior tab is disposed on an anterior portion of the frame. A posterior tab is on a posterior portion of the self-expanding frame. The frame may be designed so that any portion may expand sequentially in any desired order. For example, a portion of the first anterior tab and a portion of the posterior tab may partially self-expand first. Next, the first anterior tab may fully self-expand before the posterior tab fully self-expands. The posterior tab may fully self-expand next followed by the ventricular skirt, or the ventricular skirt may self-expand next followed by full expansion of the posterior tab.Type: GrantFiled: December 9, 2019Date of Patent: August 16, 2022Assignee: Neovasc Tiara Inc.Inventors: Randy Matthew Lane, Colin A. Nyuli, Alexei J. Marko, Krista L. Neale
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Patent number: 11389291Abstract: A method for delivering a prosthetic valve to a patient's heart having a native valve with a plurality of valve leaflets includes providing a delivery device with a prosthetic valve, advancing the delivery device toward the native valve, and expanding a portion of the prosthetic valve to form a flanged region that is upstream of the valve leaflets. One or more tabs on the prosthetic valve are released so that they expand outward to a position that is transverse to the longitudinal axis of the prosthetic valve. The position of the prosthetic valve is adjusted relative to the valve leaflets and rapid pacing is applied to the patient's heart so that the valve leaflets move inward toward the prosthetic valve or the delivery device. The tabs are further released to allow the tabs to move into their final positions.Type: GrantFiled: June 13, 2019Date of Patent: July 19, 2022Assignee: Neovase Tiara Inc.Inventors: Randy Matthew Lane, Alexei J. Marko, Colin A. Nyuli, Krista L. Neale
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Patent number: 11389294Abstract: A device for loading a prosthesis onto a delivery system includes a first housing having a central bore, One or more actuators on the first housing may be actuated radially inward to selectively compress a discrete portion of the prosthesis disposed in the central bore.Type: GrantFiled: February 5, 2021Date of Patent: July 19, 2022Assignee: Neovasc Tiara Inc.Inventors: Colin A. Nyuli, Randy Matthew Lane
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Publication number: 20210169648Abstract: A device for loading a prosthesis onto a delivery system includes a first housing having a central bore, One or more actuators on the first housing may be actuated radially inward to selectively compress a discrete portion of the prosthesis disposed in the central bore.Type: ApplicationFiled: February 5, 2021Publication date: June 10, 2021Inventors: Colin A. Nyuli, Randy Matthew Lane
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Patent number: 10940001Abstract: A device for loading a prosthesis onto a delivery system includes a first housing having a central bore. One or more actuators on the first housing may be actuated radially inward to selectively compress a discrete portion of the prosthesis disposed in the central bore.Type: GrantFiled: March 7, 2019Date of Patent: March 9, 2021Inventors: Colin A. Nyuli, Randy Matthew Lane
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Publication number: 20210030542Abstract: A sequentially deployed prosthetic cardiac valve includes a self-expanding frame having an atrial skirt, a ventricular skirt, and an annular region disposed therebetween. A first anterior tab is disposed on an anterior portion of the frame. A posterior tab is on a posterior portion of the self-expanding frame. The frame may be designed so that any portion may expand sequentially in any desired order. For example, a portion of the first anterior tab and a portion of the posterior tab may partially self-expand first. Next, the first anterior tab may fully self-expand before the posterior tab fully self-expands. The posterior tab may fully self-expand next followed by the ventricular skirt, or the ventricular skirt may self-expand next followed by full expansion of the posterior tab.Type: ApplicationFiled: October 21, 2020Publication date: February 4, 2021Inventors: Randy Matthew Lane, Colin A. Nyuli, Alexei J. Marko, Krista L. Neale
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Patent number: 10856984Abstract: A sequentially deployed prosthetic cardiac valve includes a self-expanding frame having an atrial skirt, a ventricular skirt, and an annular region disposed therebetween. A first anterior tab is disposed on an anterior portion of the frame. A posterior tab is on a posterior portion of the self-expanding frame. The frame may be designed so that any portion may expand sequentially in any desired order. For example, a portion of the first anterior tab and a portion of the posterior tab may partially self-expand first. Next, the first anterior tab may fully self-expand before the posterior tab fully self-expands. The posterior tab may fully self-expand next followed by the ventricular skirt, or the ventricular skirt may self-expand next followed by full expansion of the posterior tab.Type: GrantFiled: August 24, 2018Date of Patent: December 8, 2020Assignee: Neovasc Tiara Inc.Inventors: Randy Matthew Lane, Colin A. Nyuli, Alexei J. Marko, Krista L. Neale