Patents by Inventor Colin Andrew McLean Semple

Colin Andrew McLean Semple has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20040053283
    Abstract: A nucleotide acid sequence is provided encoding a protein having NAALAdase like activity NALADase activity has been found to be decreased in schizophrenic brain tissue. Its encoded protein can be used to screen for glutamate peptidase modulators.
    Type: Application
    Filed: September 8, 2003
    Publication date: March 18, 2004
    Inventors: Colin Andrew Mclean Semple, Donald Robert Dunbar
  • Publication number: 20030152973
    Abstract: The present invention provides a full length cDNA sequence that codes for a G-protein coupled receptor, as well as the complete gene and the encoded protein. The present invention provides a recombinant cell line expressing these receptors at appropriate levels such that novel compounds active at these receptors may be identified for therapeutic use. The receptor sequence described in this invention is a member of a novel GPCR receptor sub-family which has no known endogenous ligand. This cDNA can be used to identify novel compounds active at the receptor for therapeutic intervention especially in the field of CNS disorders, more in particular for the treatment of bipolar affective disorder (BPAD). The nucleotide sequence of this gene could he used for diagnostic purposes in psychiatric patients and susceptible populations.
    Type: Application
    Filed: February 3, 2003
    Publication date: August 14, 2003
    Inventors: Morag A Grassie, Derek Gatherer, Colin Andrew McLean Semple