Patents by Inventor Colin Brown

Colin Brown has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240124921
    Abstract: Detecting analytes using proximity-induced tagmentation, strand invasion, restriction, or ligation is provided herein. In some examples, detecting an analyte includes coupling a donor recognition probe to a first portion of the analyte. The donor recognition probe includes a first recognition element specific to the first portion of the analyte, a first oligonucleotide corresponding to the first portion, and a transposase coupled to the first recognition element and the first oligonucleotide. An acceptor recognition probe is coupled to a second portion of the analyte. The acceptor recognition probe includes a second recognition element specific to the second portion of the analyte and a second oligonucleotide coupled to the second recognition element and corresponding to the second portion. The transposase is used to generate a reporter polynucleotide including the first and second oligonucleotides. The analyte is detected based on the reporter including comprising the first and second oligonucleotides.
    Type: Application
    Filed: December 21, 2023
    Publication date: April 18, 2024
    Inventors: Andrew KENNEDY, Sarah SHULTZABERGER, Kayla BUSBY, Colin BROWN, Andrew PRICE, Eric VERMAAS, Rigoberto PANTOJA, Matthew Feeley, Jennifer ZOU, Yong LI, Sepideh ALMASI, Anindita DUTTA, Michelle ALVAREZ
  • Publication number: 20240127906
    Abstract: This disclosure describes methods, non-transitory computer readable media, and systems that can use a computationally efficient model to determine a corrected methylation-level value for a specific sample nucleotide sequence. For instance, the disclosed systems determine a false positive rate and a false negative rate at which a given methylation sequencing assay converts cytosine bases. Based on the determined false positive rate and false negative rate, the disclosed systems determine a corrected methylation-level value that corrects for a bias of the given methylation sequencing assay.
    Type: Application
    Filed: October 10, 2023
    Publication date: April 18, 2024
    Inventors: Qi Wang, Suzanne Rohrback, Sarah Shultzaberger, Rebekah Karadeema, Leslie Beh Yee Ming, James Baye, Colin Brown
  • Patent number: 11952773
    Abstract: A pre-fabricated wall system can include a first thin wall module and a second thin wall module. The two thin wall modules have a depth defined by a distance from a front surface of each thin wall module to aback surface of each thin wall module. The pre-fabricated wall system can further include a vertical connection post that has a first connection interface on a first side configured to secure to the first thin wall module. The first connection interface can include a first channel. The vertical connection post can also include a second connection interface on a second side opposite the first side configured to secure to the second thin wall module. The second connection interface can include a second channel. The two thin wall modules can be parallel or co-planar to one another when the two thin wall modules are secured to the vertical connection post.
    Type: Grant
    Filed: February 21, 2020
    Date of Patent: April 9, 2024
    Assignee: DIRTT ENVIRONMENTAL SOLUTIONS LTD.
    Inventors: Geoff W. Gosling, Thomas A. Brown, Colin V. Blehm, Taylor W. Merchant
  • Publication number: 20240087161
    Abstract: Systems and methods are provided for estimating the 3D joint location of skeleton joints from an image segment of an object and a 2D joint heatmaps comprising 2D locations of skeleton joints on the image segment. This includes applying the image segment and 2D joint heatmaps to a convolutional neural network containing at least one 3D convolutional layer block, wherein the 2D resolution is reduced at each 3D convolutional layer and the depth resolution is expanded to produce an estimated depth for each joint. Combining the 2D location of each kind of joint with the estimated depth of the kind of joint generates an estimated 3D joint position of the skeleton joint.
    Type: Application
    Filed: November 22, 2023
    Publication date: March 14, 2024
    Inventors: Colin Brown, Louis Harbour
  • Patent number: 11875529
    Abstract: Systems and methods are provided for estimating the 3D joint location of skeleton joints from an image segment of an object and a 2D joint heatmaps comprising 2D locations of skeleton joints on the image segment. This includes applying the image segment and 2D joint heatmaps to a convolutional neural network containing at least one 3D convolutional layer block, wherein the 2D resolution is reduced at each 3D convolutional layer and the depth resolution is expanded to produce an estimated depth for each joint. Combining the 2D location of each kind of joint with the estimated depth of the kind of joint generates an estimated 3D joint position of the skeleton joint.
    Type: Grant
    Filed: June 1, 2022
    Date of Patent: January 16, 2024
    Assignee: HINGE HEALTH, INC.
    Inventors: Colin Brown, Louis Harbour
  • Publication number: 20230313271
    Abstract: This disclosure describes methods, non-transitory computer readable media, and systems that can use a machine-learning to determine factors or scores indicating an error level with which a given methylation assay detects methylation of cytosine bases. For instance, the disclosed systems use a machine-learning model to generate a bias score indicating a degree to which a given methylation assay errs in detecting cytosine methylation when specific sequence contexts surround such cytosines compared to other sequence contexts. The machine-learning model may take various forms of models, including a decision-tree model, a neural network, or a combination of a decision-tree model and a neural network. In some cases, the disclosed system combines or uses bias scores from multiple machine-learning models to generate a consensus bias score.
    Type: Application
    Filed: February 22, 2023
    Publication date: October 5, 2023
    Inventors: Steven Norberg, Luis Fernando Camarillo Guerrero, Colin Brown, Andrea Manzo, Sarah E. Shultzaberger, Michael Eberle, Sepideh Almasi, Suzanne Rohrback, Pascale Mathonet, Egor Dolzhenko
  • Publication number: 20230274145
    Abstract: This disclosure describes an activity recognition system for asymmetric (e.g., left- and right- handed) activities that leverages the symmetry intrinsic to most human and animal bodies. Specifically, described is 1) a human activity recognition system that only recognizes handed activities but is inferenced twice, once with input flipped, to identify both left- and right- handed activities and 2) a training method for learning-based implementations of the aforementioned system that flips all training instances (and associated labels) to appear left-handed and in doing so, balances the training dataset between left- and right-handed activities.
    Type: Application
    Filed: May 3, 2023
    Publication date: August 31, 2023
    Inventors: Colin Brown, Andrey Tolstikhin
  • Publication number: 20230267331
    Abstract: This disclosure describes an activity recognition system for asymmetric (e.g., left- and right-handed) activities that leverages the symmetry intrinsic to most human and animal bodies. Specifically, described is 1) a human activity recognition system that only recognizes handed activities but is inferenced twice, once with input flipped, to identify both left- and right-handed activities and 2) a training method for learning-based implementations of the aforementioned system that flips all training instances (and associated labels) to appear left-handed and in doing so, balances the training dataset between left- and right-handed activities.
    Type: Application
    Filed: May 3, 2023
    Publication date: August 24, 2023
    Inventors: Colin Brown, Andrey Tolstikhin
  • Publication number: 20230175954
    Abstract: A method of directly measuring moisture content in an oil-filled transformer includes using an optical fiber that having a grating sensor, such as a Fiber Bragg grating, defined in the optical fiber. The various conductors (windings) in the transformer are insulated using an insulator such as paper and insulating oil is filled inside the transformer. Moisture in the transformer is absorbed by the paper that surrounds the windings. A moisture content at a specific location can be measured by placing the optical fiber with the grating sensor directly at the specific location to be measured. A physical parameter of the paper that absorbed moisture changes over time, causing a change in the grating sensor of the optical fiber which changes the spectral response of optical signals that are reflected by the grating sensor. The method provides an accurate method of measuring the moisture inside the transformer at the specific location.
    Type: Application
    Filed: December 5, 2022
    Publication date: June 8, 2023
    Inventors: Sri Krishna Bukya, Emilio Morales Cruz, Anis Zribi, Andre Pelletreau, Colin Brown, Paul Donegan
  • Patent number: 11657281
    Abstract: This disclosure describes an activity recognition system for asymmetric (e.g. left- and right-handed) activities that leverages the symmetry intrinsic to most human and animal bodies. Specifically, described is 1) a human activity recognition system that only recognizes handed activities but is inferenced twice, once with input flipped, to identify both left- and right-handed activities and a training method for learning-based implementations of the aforementioned system that flips all training instances (and associated labels) to appear left-handed and in doing so, balances the training dataset between left- and right-handed activities.
    Type: Grant
    Filed: March 12, 2020
    Date of Patent: May 23, 2023
    Assignee: Hinge Health, Inc.
    Inventors: Colin Brown, Andrey Tolstikhin
  • Publication number: 20220292714
    Abstract: Systems and methods are provided for estimating the 3D joint location of skeleton joints from an image segment of an object and a 2D joint heatmaps comprising 2D locations of skeleton joints on the image segment. This includes applying the image segment and 2D joint heatmaps to a convolutional neural network containing at least one 3D convolutional layer block, wherein the 2D resolution is reduced at each 3D convolutional layer and the depth resolution is expanded to produce an estimated depth for each joint. Combining the 2D location of each kind of joint with the estimated depth of the kind of joint generates an estimated 3D joint position of the skeleton joint.
    Type: Application
    Filed: June 1, 2022
    Publication date: September 15, 2022
    Inventors: Colin Brown, Louis Harbour
  • Patent number: 11354817
    Abstract: Systems and methods are provided for estimating the 3D joint location of skeleton joints from an image segment of an object and a 2D joint heatmaps comprising 2D locations of skeleton joints on the image segment. This includes applying the image segment and 2D joint heatmaps to a convolutional neural network containing at least one 3D convolutional layer block, wherein the 2D resolution is reduced at each 3D convolutional layer and the depth resolution is expanded to produce an estimated depth for each joint. Combining the 2D location of each kind of joint with the estimated depth of the kind of joint generates an estimated 3D joint position of the skeleton joint.
    Type: Grant
    Filed: December 14, 2021
    Date of Patent: June 7, 2022
    Assignee: HINGE HEALTH, INC.
    Inventors: Colin Brown, Louis Harbour
  • Publication number: 20220148296
    Abstract: This disclosure describes an activity recognition system for asymmetric (e.g. left- and right- handed) activities that leverages the symmetry intrinsic to most human and animal bodies. Specifically, described is 1) a human activity recognition system that only recognizes handed activities but is inferenced twice, once with input flipped, to identify both left- and right-handed activities and a training method for learning-based implementations of the aforementioned system that flips all training instances (and associated labels) to appear left-handed and in doing so, balances the training dataset between left- and right-handed activities.
    Type: Application
    Filed: March 12, 2020
    Publication date: May 12, 2022
    Applicant: Hinge Health, Inc.
    Inventors: Colin Brown, Andrey Tolstikhin
  • Publication number: 20220108470
    Abstract: Systems and methods are provided for estimating the 3D joint location of skeleton joints from an image segment of an object and a 2D joint heatmaps comprising 2D locations of skeleton joints on the image segment. This includes applying the image segment and 2D joint heatmaps to a convolutional neural network containing at least one 3D convolutional layer block, wherein the 2D resolution is reduced at each 3D convolutional layer and the depth resolution is expanded to produce an estimated depth for each joint. Combining the 2D location of each kind of joint with the estimated depth of the kind of joint generates an estimated 3D joint position of the skeleton joint.
    Type: Application
    Filed: December 14, 2021
    Publication date: April 7, 2022
    Inventors: Colin Brown, Louis Harbour
  • Patent number: 9940545
    Abstract: A method, apparatus and computer program product are hereby provided to detect anatomical elements in a medical image. In this regard, the method, apparatus, and computer program product may receive a test image and generate a classified image by applying an image classifier to the test image. The image classifier may include at least one decision tree for evaluating at least one pixel value of the test image and the classified image may include a plurality of pixel values. Each pixel value may be associated with a probability that an anatomical element is located at the pixel location. The method, apparatus, and computer program product may also evaluate the classified image using an anatomical model to detect at least one anatomical element within the classified image.
    Type: Grant
    Filed: September 20, 2013
    Date of Patent: April 10, 2018
    Assignee: CHANGE HEALTHCARE LLC
    Inventors: Mahmoud Ramze Rezaee, Andrew Top, Colin Brown, Ghassan Hamarneh
  • Publication number: 20150086091
    Abstract: A method, apparatus and computer program product are hereby provided to detect anatomical elements in a medical image. In this regard, the method, apparatus, and computer program product may receive a test image and generate a classified image by applying an image classifier to the test image. The image classifier may include at least one decision tree for evaluating at least one pixel value of the test image and the classified image may include a plurality of pixel values. Each pixel value may be associated with a probability that an anatomical element is located at the pixel location. The method, apparatus, and computer program product may also evaluate the classified image using an anatomical model to detect at least one anatomical element within the classified image.
    Type: Application
    Filed: September 20, 2013
    Publication date: March 26, 2015
    Applicant: McKesson Financial Holdings
    Inventors: Mahmoud Ramze Rezaee, Andrew Top, Colin Brown, Ghassan Hamarneh
  • Patent number: 8642574
    Abstract: A method of preventing or reducing the incidence of post-operative adhesions in or associated with a body cavity, which comprises introducing into the body cavity a composition containing an aqueous solution or suspension or gel formulation containing the polysaccharide dextrin.
    Type: Grant
    Filed: November 17, 2011
    Date of Patent: February 4, 2014
    Assignee: Innovata Limited
    Inventor: Colin Brown
  • Publication number: 20120115810
    Abstract: A method of preventing or reducing the incidence of post-operative adhesions in or associated with a body cavity, which comprises introducing into the body cavity a composition containing an aqueous solution or suspension or gel formulation containing the polysaccharide dextrin.
    Type: Application
    Filed: November 17, 2011
    Publication date: May 10, 2012
    Inventor: COLIN BROWN
  • Patent number: 8158610
    Abstract: A method of reducing the incidence of post-operative adhesions in or associated with a body cavity, which comprises introducing into the body cavity a composition containing an aqueous solution or suspension or gel formulation containing the polysaccharide dextrin.
    Type: Grant
    Filed: May 7, 2010
    Date of Patent: April 17, 2012
    Assignee: Innovata Limited
    Inventor: Colin Brown
  • Patent number: 8063027
    Abstract: A method of preventing or reducing the incidence of post-operative adhesions in or associated with a body cavity, which comprises introducing into the body cavity a composition containing an aqueous solution or suspension or gel formulation containing the polysaccharide dextrin.
    Type: Grant
    Filed: October 25, 2005
    Date of Patent: November 22, 2011
    Assignee: Innovata Limited
    Inventor: Colin Brown