Patents by Inventor Colin Buss

Colin Buss has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Lung protease nanosensors and uses thereof
    Patent number: 12173349
    Abstract: Aspects of the present disclosure relate to methods and compositions useful for in vivo and/or in vitro profiling of proteases present in the lung. In some embodiments, the disclosure provides methods of in vivo enzymatic processing of exogenous molecules followed by detection of detectable markers as representative of the presence of active proteases associated with a lung disease, for example, lung cancer and lung infections. In some embodiments, the disclosure provides compositions and methods for production of a lung disease signature and diagnosis of lung disease.
    Type: Grant
    Filed: September 25, 2019
    Date of Patent: December 24, 2024
    Assignee: Massachusetts Institute of Technology
    Inventors: Sangeeta N. Bhatia, Jesse Kirkpatrick, Jaideep S. Dudani, Colin Buss, Andrew David Warren
  • LUNG PROTEASE NANOSENSORS AND USES THEREOF
    Publication number: 20200096514
    Abstract: Aspects of the present disclosure relate to methods and compositions useful for in vivo and/or in vitro profiling of proteases present in the lung. In some embodiments, the disclosure provides methods of in vivo enzymatic processing of exogenous molecules followed by detection of detectable markers as representative of the presence of active proteases associated with a lung disease, for example, lung cancer and lung infections. In some embodiments, the disclosure provides compositions and methods for production of a lung disease signature and diagnosis of lung disease.
    Type: Application
    Filed: September 25, 2019
    Publication date: March 26, 2020
    Applicant: Massachusetts Institute of Technology
    Inventors: Sangeeta N. Bhatia, Jesse Kirkpatrick, Jaideep S. Dudani, Colin Buss, Andrew David Warren