Patents by Inventor Colin DRABE

Colin DRABE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Aldehyde-modified hyaluronic acid, method for preparing same and applications thereof
    Patent number: 12667533
    Abstract: A modified hyaluronic acid derivative is described having the —CH2-OH group of the N-acetyl-D-glucosamine unit (GlcNAc) modified to an aldehyde group having the structure —CH2-O—CH2-CHO where the degree of modification is 1.0% to 15.0% for preparing a crosslinked hydrogel for use in aesthetic applications. The modified hyaluronic acid derivative is prepared by reacting a glycerol-modified hyaluronic acid with an oxidizing agent such as periodate.
    Type: Grant
    Filed: December 18, 2019
    Date of Patent: June 30, 2026
    Assignee: Merz Pharma GmbH & Co. KGaA
    Inventors: Patrick Plitt, Colin Drabe, Sibylle Mueller, Radovan Vukicevic, Jens Neubauer, Charlotte Reither
  • CROSS-LINKING POLYSACCHARIDE WITH FIBROIN AND USES OF THE OBTAINED MATERIAL
    Publication number: 20240317900
    Abstract: The invention proposes a method for preparing a cross-linked material, comprising forming amide bonds that conjugate one or more fibroin moieties with one or more polysaccharide moieties. The invention further relates to a cross-linked material obtainable from such method and to an injectable composition comprising the obtained cross-linked material. The cross-linked material can be a hydrogel and/or a super-volumizer and can be used in cosmetic and pharmaceutical applications.
    Type: Application
    Filed: June 22, 2022
    Publication date: September 26, 2024
    Inventors: Radovan VUKICEVIC, Colin DRABE, Patrick PLITT, Jens NEUBAUER
  • ALDEHYDE-MODIFIED HYALURONIC ACID, METHOD FOR PREPARING SAME AND APPLICATIONS THEREOF
    Publication number: 20220062151
    Abstract: The present invention relates to a modified hyaluronic acid derivative, wherein the —CH2—OH group of at least one N-acetyl-D-glucosamine unit is modified into an aldehyde group having the structure —CH2—O—CH2—CHO, methods for preparing same and applications thereof.
    Type: Application
    Filed: December 18, 2019
    Publication date: March 3, 2022
    Inventors: Patrick PLITT, Colin DRABE, Sibylle MUELLER, Radovan VUKICEVIC, Jens NEUBAUER, Charlotte REITHER
  • In vivo accelerated degradation of polysaccharide-containing fillers
    Patent number: 10413491
    Abstract: The present invention relates to a composition for the in vivo degradation of polysaccharide-containing fillers by radical degradation. The composition of the invention comprising at least one source of oxygen free radicals and at least one catalyst of oxygen free radical generation from the at least one source of oxygen free radicals. The present invention further relates to methods and uses of said composition for filler correction or reversal.
    Type: Grant
    Filed: April 1, 2015
    Date of Patent: September 17, 2019
    Assignee: MERZ PHARMA GMBH & CO. KGAA
    Inventors: Lubin Belkovi, Franck Villain, Andreas Krause, Colin Drabe
  • IN VIVO ACCELERATED DEGRADATION OF POLYSACCHARIDE-CONTAINING FILLERS
    Publication number: 20170172865
    Abstract: The present invention relates to a composition for the in vivo degradation of polysaccharide-containing fillers by radical degradation. The composition of the invention comprising at least one source of oxygen free radicals and at least one catalyst of oxygen free radical generation from the at least one source of oxygen free radicals. The present invention further relates to methods and uses of said composition for filler correction or reversal.
    Type: Application
    Filed: April 1, 2015
    Publication date: June 22, 2017
    Inventors: Lubin BELKOVI, Franck VILLAIN, Andreas KRAUSE, Colin DRABE