Patents by Inventor Colin Groom

Colin Groom has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Crystal structure of phosphodiesterase 5 and use thereof
    Publication number: 20070015205
    Abstract: The present invention relates, inter alia, to the crystal structures of a phosphodiesterase 5 (PDE5) and PDE5/PDE5 ligand complex and their uses in identifying PDE5 ligands, including PDE5 inhibitor compounds. The present invention also relates to methods of identifying such PDE5 inhibitor compounds and their medical use. Also contemplated by the present invention are crystals of PDE5/PDE5 inhibitor complexes.
    Type: Application
    Filed: October 24, 2002
    Publication date: January 18, 2007
    Inventors: David Brown, Colin Groom, Andrew Hopkins, Timothy Jenkins, Sarah Kamp, Margaret O'Gara, Heather Ringrose, Colin Robinson, Wendy Taylor
  • Crystal structure
    Publication number: 20050202549
    Abstract: The present invention relates to the soakable crystals of a phosphodiesterase 5 (PDE5) and their uses in identifying PDE5 ligands, including PDE5 ligands and inhibitor compounds. The present invention also relates to methods of identifying such PDE5 inhibitor compounds and their medical use. The present invention additionally relates to crystals of PDE5 into which ligands may be soaked and crystals of PDE5 comprising PDE5 ligands that have been soaked into the crystal.
    Type: Application
    Filed: April 30, 2004
    Publication date: September 15, 2005
    Inventors: David Brown, Colin Groom, Andrew Hopkins, Timothy Jenkins, Sarah Kamp, Margaret O'Gara, Heather Ringrose, Colin Robinson, Wendy Taylor
  • System and method for the computer-assisted identification of drugs and indications
    Publication number: 20050060305
    Abstract: A pharmaceutical knowledge base is provided that contains multiple information items stored in at least one computer. Pharmaceutical knowledge is represented in a multi-dimensional coordinate space having at least first, second and third axes, where the first axis pertains to diseases, the second axis pertains to targets, and the third axis pertains to drug compounds. Pharmaceutical knowledge may be mapped into the multi-dimensional coordinate space by assigning each information item one or more locations in the space, dependent upon the data contained within the information item. This mapping may then be used to reveal hitherto unappreciated connections between the axes, such as the potential use of a particular compound or target for treating a certain disease.
    Type: Application
    Filed: September 15, 2004
    Publication date: March 17, 2005
    Applicant: Pfizer Inc.
    Inventors: Andrew Hopkins, Lee Harland, Jerry Lanfear, Colin Groom, Ian Parsons, Tony Parsons, Mark Zaretti, Mark Burfoot, Lee Beeley