Patents by Inventor Colin Halford

Colin Halford has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10370728
    Abstract: Described are probes and methods for detecting antibiotic susceptibility of a specimen. The method comprises contacting the specimen with an oligonucleotide probe that specifically hybridizes with a target nucleic acid sequence region of ribosomal RNA. The target sequence is at the junction between a pre-ribosomal RNA tail and mature ribosomal RNA of 23S or 16S rRNA. Performing the method in the presence and absence of an antibiotic permits detection of antibiotic susceptibility.
    Type: Grant
    Filed: May 3, 2013
    Date of Patent: August 6, 2019
    Assignees: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE UNITED STATES OF AMERICA REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS
    Inventors: David A. Haake, Colin Halford, Jane T. Babbitt, Bernard M. Churchill
  • Publication number: 20160160268
    Abstract: Described are methods for detecting susceptibility of a specimen to antibiotics, and particularly for enhancing such susceptibility testing for beta lactam antibiotics and antibiotics that bind to penicillin-binding proteins. The method comprises contacting the specimen with an oligonucleotide probe that specifically hybridizes with a target nucleic acid sequence region of ribosomal RNA. The target sequence is mature ribosomal RNA or at the splice site between a pre-ribosomal RNA tail and mature ribosomal RNA. Performing the method in the presence and absence of an antibiotic permits determination of antibiotic susceptibility. Rapid susceptibility testing is enabled by the addition of the PBP2-specific antibiotic, amdinocillin.
    Type: Application
    Filed: July 22, 2014
    Publication date: June 9, 2016
    Applicants: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, UNITED STATES GOVERNMENT REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS
    Inventors: David A. HAAKE, Bernard M. CHURCHILL, Colin HALFORD
  • Publication number: 20150104789
    Abstract: Described are probes and methods for detecting antibiotic susceptibility of a specimen. The method comprises contacting the specimen with an oligonucleotide probe that specifically hybridizes with a target nucleic acid sequence region of ribosomal RNA. The target sequence is at the junction between a pre-ribosomal RNA tail and mature ribosomal RNA of 23S or 16S rRNA. Performing the method in the presence and absence of an antibiotic permits detection of antibiotic susceptibility.
    Type: Application
    Filed: May 3, 2013
    Publication date: April 16, 2015
    Applicants: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE UNITED STATES GOVERNMENT REPRESENTED BY THE DEPARTMENT OF VETERAN AFFAIRS
    Inventors: David A. Haake, Colin Halford, Jane T. Babbitt, Bernard M. Churchill