Abstract: A hypodermic syringe (1, 2) includes a needle (3) covered by a needle sheath (4) that comprises a tubular sheath body (5) with a removable end cap (6). Injectant is transferred into the main body (1) of the syringe by removing the end cap, inserting the needle together with the sheath body (5) into a source of injectant and operating the plunger so as to draw the injectant through open end (6) of the plunger through the needle into the main body. The process is carried out without exposing the needle to the user's touch.

Abstract: A syringe has a capsule assembly (1) which is pre-loaded with injectant fluid (1.10) and is provided with a needle (1.2) that is covered by a sealed needle sheath (1.4). The capsule assembly (1) is placed into a housing (2). The sealed capsule is prepared for use by removal of the sealed needle sheath (1.4). A plunger (4) with an associated piston (5) is used to input the fluid (1.10). The capsule assembly (1) including the needle (1.2) is automatically retracted into the housing (2) after use.