Patents by Inventor Colin Lloyd
Colin Lloyd has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230259972Abstract: Devices, systems, and methods for allocating consumer communications can include obtaining consumer activity data, designating a number of consumer communication campaigns concerning consumer features based on the consumer activity data, entering consumer activity data as inputs to one machine learning model for each determined consumer communication campaign, each machine learning model configured determine a campaign consumer activation profile based on the entered consumer activity data, and assigning the consumer communication campaigns to consumers based on the determined campaign consumer activation profiles.Type: ApplicationFiled: February 10, 2023Publication date: August 17, 2023Inventors: Yao XIE, Anupriya AGRAWAL, Ann EHNERT, Chace MACMULLAN, Colin LLOYD, Thomas E. HENRY, JR., Yifan ZHAO
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Publication number: 20220265010Abstract: Embodiments described herein relate generally to apparatuses and methods relating to mobility assist devices including, for example, walking canes. In some embodiments, a mobility assist device can include a wrist stabilizer and one or more exercising elements for enabling a user to perform torsion, rotation, grip, and/or other exercises.Type: ApplicationFiled: February 9, 2022Publication date: August 25, 2022Inventor: Colin Lloyd CAMPBELL
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Patent number: 10876158Abstract: The invention provides methods for pairwise sequencing of a double-stranded polynucleotide template, which methods result in the sequential determination of nucleotide sequences in two distinct and separate regions of the polynucleotide template.Type: GrantFiled: June 11, 2018Date of Patent: December 29, 2020Assignee: Illumina Cambridge LimitedInventors: Geoffrey Paul Smith, Jonathan Mark Boutell, Colin Lloyd Barnes, Roberto Rigatti, Niall Anthony Gormley, David Bentley, Tobias William Barr Ost, Vincent Peter Smith, Graham John Worsley, Eric Hans Vermaas
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Publication number: 20200399692Abstract: The invention provides modified nucleotide or nucleoside molecule comprising a purine or pyrimidine base and a ribose or deoxyribose sugar moiety having a removable 3?-OH blocking group covalently attached thereto, such that the 3? carbon atom has attached a group of the structure —O—Z wherein Z is any of —C(R?)2-O—R?, —C(R?)2-N(R?)2, —C(R?)2-N(H)R?, —C(R?)2-S—R? and —C(R?)2-F, wherein each R? is or is part of a removable protecting group; each R? is independently a hydrogen atom, an alkyl, substituted alkyl, arylalkyl, alkenyl, alkynyl, aryl, heteroaryl, heterocyclic, acyl, cyano, alkoxy, aryloxy, heteroaryloxy or amido group, or a detectable label attached through a linking group; or (R?)2 represents an alkylidene group of formula ?C(R??)2 wherein each R?? may be the same or different and is selected from the group comprising hydrogen and halogen atoms and alkyl groups; and wherein said molecule may be reacted to yield an intermediate in which each R? is exchanged for H or, where Z is —C(R?)2-F, the F is exType: ApplicationFiled: May 18, 2020Publication date: December 24, 2020Inventors: John MILTON, Xiaolin WU, Mark Edward Brennan SMITH, Joseph BRENNAN, Colin Lloyd BARNES, Xiaohai LIU, Silke RUEDIGER
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Patent number: 10710046Abstract: The invention relates to methods of generating templates for a nucleic acid sequencing reaction which comprise: providing at least one double-stranded nucleic acid molecule, wherein both strands of the double-stranded nucleic acid molecule are attached to a solid support at the 5? end, cleaving one or both strands of the double-stranded nucleic acid molecule, and subjecting the cleaved strand(s) to denaturing conditions to remove the portion of the cleaved strand(s) not attached to the solid support, thereby generating a partially or substantially single-stranded template for a nucleic acid sequencing reaction.Type: GrantFiled: June 18, 2018Date of Patent: July 14, 2020Assignee: Illumina Cambridge LimitedInventors: Xiaohai Liu, John Milton, Geoffrey Paul Smith, Colin Lloyd Barnes, Isabelle Rasolonjatovo, Roberto Rigatti, Xiaolin Wu, Tobias William Barr Ost, Graham John Worsley, David James Earnshaw, Gerardo Turcatti, Anthony Romieu
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Publication number: 20200115747Abstract: Nucleosides and nucleotides are disclosed that are linked to detectable labels via a cleavable linker group.Type: ApplicationFiled: December 23, 2019Publication date: April 16, 2020Inventors: Shankar BALASUBRAMANIAN, Colin Lloyd BARNES, Xiaohai LIU, Xiaolin WU, John MILTON
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Publication number: 20200109448Abstract: Nucleosides and nucleotides are disclosed that are linked to detectable labels via a cleavable linker group.Type: ApplicationFiled: October 4, 2019Publication date: April 9, 2020Inventors: Shankar BALASUBRAMANIAN, Colin Lloyd BARNES, Xiaohai LIU, John MILTON
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Publication number: 20200017908Abstract: The invention provides modified nucleotide or nucleoside molecule comprising a purine or pyrimidine base and a ribose or deoxyribose sugar moiety having a removable 3?-OH blocking group covalently attached thereto, such that the 3? carbon atom has attached a group of the structure —O—Z wherein Z is any of —C(R?)2-O—R?, —C(R?)2-N(R?)2, —C(R?)2-N(H)R?, —C(R?)2-S—R? and —C(R?)2-F, wherein each R? is or is part of a removable protecting group; each R? is independently a hydrogen atom, an alkyl, substituted alkyl, arylalkyl, alkenyl, alkynyl, aryl, heteroaryl, heterocyclic, acyl, cyano, alkoxy, aryloxy, heteroaryloxy or amido group, or a detectable label attached through a linking group; or (R?)2 represents an alkylidene group of formula=C(R??)2 wherein each R?? may be the same or different and is selected from the group comprising hydrogen and halogen atoms and alkyl groups; and wherein said molecule may be reacted to yield an intermediate in which each R? is exchanged for H or, where Z is —C(R?)2-F, the F is excType: ApplicationFiled: July 26, 2019Publication date: January 16, 2020Inventors: John MILTON, Xiaolin WU, Mark Edward Brennan SMITH, Joseph BRENNAN, Colin Lloyd BARNES, Xiaohai LIU, Silke RUEDIGER
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Patent number: 10519496Abstract: Nucleosides and nucleotides are disclosed that are linked to detectable labels via a cleavable linker group.Type: GrantFiled: March 27, 2017Date of Patent: December 31, 2019Assignee: Illumina Cambridge LimitedInventors: Shankar Balasubramanian, Colin Lloyd Barnes, Xiaohai Liu, Xiaolin Wu, John Milton
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Patent number: 10480025Abstract: Nucleosides and nucleotides are disclosed that are linked to detectable labels via a cleavable linker group.Type: GrantFiled: July 5, 2016Date of Patent: November 19, 2019Assignee: Illumina Cambridge LimitedInventors: Shankar Balasubramanian, Colin Lloyd Barnes, Xiaohai Liu, John Milton, Xiaolin Wu, Harold Swerdlow
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Publication number: 20180363047Abstract: The invention provides methods for pairwise sequencing of a double-stranded polynucleotide template, which methods result in the sequential determination of nucleotide sequences in two distinct and separate regions of the polynucleotide template.Type: ApplicationFiled: June 11, 2018Publication date: December 20, 2018Applicant: Illumina Cambridge LimitedInventors: Geoffrey Paul Smith, Jonathan Mark Boutell, Colin Lloyd Barnes, Roberto Rigatti, Niall Anthony Gormley, David Bentley, Tobias William Barr Ost, Vincent Peter Smith, Graham John Worsley, Eric Hans Vermaas
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Publication number: 20180353926Abstract: The invention relates to methods of generating templates for a nucleic acid sequencing reaction which comprise: providing at least one double-stranded nucleic acid molecule, wherein both strands of the double-stranded nucleic acid molecule are attached to a solid support at the 5? end, cleaving one or both strands of the double-stranded nucleic acid molecule, and subjecting the cleaved strand(s) to denaturing conditions to remove the portion of the cleaved strand(s) not attached to the solid support, thereby generating a partially or substantially single-stranded template for a nucleic acid sequencing reaction.Type: ApplicationFiled: June 18, 2018Publication date: December 13, 2018Applicant: Illumina Cambridge LimitedInventors: Xiaohai Liu, John Milton, Geoffrey Paul Smith, Colin Lloyd Barnes, Isabelle Rasolonjatovo, Roberto Rigatti, Xiaolin Wu, Tobias William Barr Ost, Graham John Worsley, David James Earnshaw, Gerardo Turcatti, Anthony Romieu
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Patent number: 9999866Abstract: The invention relates to methods of generating templates for a nucleic acid sequencing reaction which comprise: providing at least one double-stranded nucleic acid molecule, wherein both strands of the double-stranded nucleic acid molecule are attached to a solid support at the 5? end, cleaving one or both strands of the double-stranded nucleic acid molecule, and subjecting the cleaved strand(s) to denaturing conditions to remove the portion of the cleaved strand(s) not attached to the solid support, thereby generating a partially or substantially single-stranded template for a nucleic acid sequencing reaction.Type: GrantFiled: October 6, 2016Date of Patent: June 19, 2018Assignee: ILLUMINA CAMBRIDGE LIMITEDInventors: Xiaohai Liu, John Milton, Geoffrey Paul Smith, Colin Lloyd Barnes, Isabelle Rasolonjatovo, Roberto Rigatti, Xiaolin Wu, Tobias William Barr Ost, Graham John Worsley, David James Earnshaw, Gerardo Turcatti, Anthony Romieu
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Patent number: 9994896Abstract: The invention provides methods for pairwise sequencing of a double-stranded polynucleotide template, which methods result in the sequential determination of nucleotide sequences in two distinct and separate regions of the polynucleotide template.Type: GrantFiled: December 17, 2014Date of Patent: June 12, 2018Assignee: ILLUMINA CAMBRIDGE LIMITEDInventors: Geoffrey Paul Smith, Jonathan Mark Boutell, Colin Lloyd Barnes, Roberto Rigatti, Niall Anthony Gormley, David Bentley, Tobias William Barr Ost, Vincent Peter Smith, Graham John Worsley, Eric Hans Vermaas
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Publication number: 20170021325Abstract: The invention relates to methods of generating templates for a nucleic acid sequencing reaction which comprise: providing at least one double-stranded nucleic acid molecule, wherein both strands of the double-stranded nucleic acid molecule are attached to a solid support at the 5? end, cleaving one or both strands of the double-stranded nucleic acid molecule, and subjecting the cleaved strand(s) to denaturing conditions to remove the portion of the cleaved strand(s) not attached to the solid support, thereby generating a partially or substantially single-stranded template for a nucleic acid sequencing reaction.Type: ApplicationFiled: October 6, 2016Publication date: January 26, 2017Inventors: Xiaohai Liu, John Milton, Geoffrey Paul Smith, Colin Lloyd Barnes, Isabelle Rasolonjatovo, Roberto Rigatti, Xiaolin Wu, Tobias William Barr Ost, Graham John Worsley, David James Earnshaw, Gerardo Turcatti, Anthony Romieu
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Patent number: 9498763Abstract: The invention relates to methods of generating templates for a nucleic acid sequencing reaction which comprise: providing at least one double-stranded nucleic acid molecule, wherein both strands of the double-stranded nucleic acid molecule are attached to a solid support at the 5? end, cleaving one or both strands of the double-stranded nucleic acid molecule, and subjecting the cleaved strand(s) to denaturing conditions to remove the portion of the cleaved strand(s) not attached to the solid support, thereby generating a partially or substantially single-stranded template for a nucleic acid sequencing reaction.Type: GrantFiled: June 12, 2015Date of Patent: November 22, 2016Assignee: Illumina Cambridge LimitedInventors: Xiaohai Liu, John Milton, Geoffrey Paul Smith, Colin Lloyd Barnes, Isabelle Rasolonjatovo, Roberto Rigatti, Xiaolin Wu, Tobias William Barr Ost, Graham John Worsley, David James Earnshaw, Gerardo Turcatti, Anthony Romieu
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Patent number: 9455880Abstract: Method and system for routing EPP requests over a network are provided. The EPP request can include XML namespace information and optionally XML sub-product information. A gateway can receive the request and analyze the namespace and in some instances, sub-product information to determine the service to which the request is directed. Thereupon, the gateway can route the request to the appropriate service by consulting a routing table that can have status and connectivity information for all the available services.Type: GrantFiled: November 19, 2012Date of Patent: September 27, 2016Assignee: VERISIGN, INC.Inventors: James Gould, Mahendra Jain, Colin Lloyd
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Publication number: 20150343410Abstract: The invention relates to methods of generating templates for a nucleic acid sequencing reaction which comprise: providing at least one double-stranded nucleic acid molecule, wherein both strands of the double-stranded nucleic acid molecule are attached to a solid support at the 5? end, cleaving one or both strands of the double-stranded nucleic acid molecule, and subjecting the cleaved strand(s) to denaturing conditions to remove the portion of the cleaved strand(s) not attached to the solid support, thereby generating a partially or substantially single-stranded template for a nucleic acid sequencing reaction.Type: ApplicationFiled: June 12, 2015Publication date: December 3, 2015Applicant: ILLUMINA CAMBRIDGE LIMITEDInventors: Xiaohai Liu, John Milton, Geoffrey Paul Smith, Colin Lloyd Barnes, Isabelle Rasolonjatovo, Roberto Rigatti, Xiaolin Wu, Tobias William Barr Ost, Graham John Worsley, David James Earnshaw, Gerardo Turcatti, Anthony Romieu
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Publication number: 20150203910Abstract: The invention provides methods for pairwise sequencing of a double-stranded polynucleotide template, which methods result in the sequential determination of nucleotide sequences in two distinct and separate regions of the polynucleotide template.Type: ApplicationFiled: December 17, 2014Publication date: July 23, 2015Applicant: ILLUMINA CAMBRIDGE LIMITEDInventors: Geoffrey Paul Smith, Jonathan Mark Boutell, Colin Lloyd Barnes, Roberto Rigatti, Niall Anthony Gormley, David Bentley, Tobias William Barr Ost, Vincent Peter Smith, Graham John Worsley, Eric Hans Vermaas
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Patent number: 9085802Abstract: The invention relates to methods of generating templates for a nucleic acid sequencing reaction which comprise: providing at least one double-stranded nucleic acid molecule, wherein both strands of the double-stranded nucleic acid molecule are attached to a solid support at the 5? end, cleaving one or both strands of the double-stranded nucleic acid molecule, and subjecting the cleaved strand(s) to denaturing conditions to remove the portion of the cleaved strand(s) not attached to the solid support, thereby generating a partially or substantially single-stranded template for a nucleic acid sequencing reaction.Type: GrantFiled: January 28, 2014Date of Patent: July 21, 2015Assignee: Illumina Cambridge LimitedInventors: Xiaohai Liu, John Milton, Geoffrey Paul Smith, Colin Lloyd Barnes, Isabelle Marie Julia Rasolonjatovo, Roberto Rigatti, Xiaolin Wu, Tobias William Barr Ost, Graham John Worsley, David James Earnshaw, Gerardo Turcatti, Anthony Romieu