Patents by Inventor Colin Malone

Colin Malone has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PNMA2-BASED CAPSIDS AND USES THEREOF
    Publication number: 20240102052
    Abstract: Disclosed herein, in certain embodiments, are recombinant PNMA2 and endogenous Gag polypeptides, capsids comprising the recombinant PNMA2 or endogenous Gag polypeptides, and methods of making and using recombinant PNMA2 and endogenous Gag polypeptides.
    Type: Application
    Filed: January 26, 2022
    Publication date: March 28, 2024
    Inventors: Colin MALONE, Oleg LAPTENKO, Adam FRAITES, Jessica CRISP, Andrey PISAREV, Anil ANGAD, Heley ONG, Zachary GILBERT, Jason D. SHEPHERD
  • ARC-BASED CAPSIDS AND USES THEREOF
    Publication number: 20230312657
    Abstract: Disclosed herein, in certain embodiments, are recombinant Arc and endogenous Gag polypeptides, and methods of using recombinant Arc and endogenous Gag polypeptides.
    Type: Application
    Filed: October 13, 2022
    Publication date: October 5, 2023
    Inventors: Colin MALONE, Ian PEIKON, Zachary GILBERT, Andrey PISAREV, Adam FRAITES, Jessica CRISP
  • VACCINE COMPOSITIONS COMPRISING ENDOGENOUS GAG POLYPEPTIDES
    Publication number: 20230201337
    Abstract: Described herein is a composition comprising: 1) an ARC polypeptide or an endogenous gag (endo-gag) polypeptide; 2) a pathogen-associated antigen; and 3) an adjuvant. Also described herein are vaccines and methods of vaccination using compositions comprising: 1) an ARC polypeptide or an endogenous gag (endo-gag) polypeptide; 2) a pathogen-associated antigen; and 3) an adjuvant.
    Type: Application
    Filed: May 17, 2021
    Publication date: June 29, 2023
    Inventors: Zachary GILBERT, Colin MALONE
  • ARC-BASED CAPSIDS AND USES THEREOF
    Publication number: 20230057793
    Abstract: Disclosed herein, in certain embodiments, are recombinant Arc and endogenous Gag polypeptides, and methods of using recombinant Arc and endogenous Gag polypeptides.
    Type: Application
    Filed: August 8, 2022
    Publication date: February 23, 2023
    Inventors: Colin MALONE, Ian PEIKON, Zachary GILBERT, Andrey PISAREV, Adam FRAITES, Jessica CRISP
  • Endogenous Gag-based capsids and uses thereof
    Patent number: 11505578
    Abstract: Nucleic acids encoding endogenous Gag peptides can be isolated from various organisms. Nucleic acids encoding various endogenous Gag polypeptides can be isolated from human DNA. The nucleic acids can be used to express endogenous Gag polypeptides that can be assembled into capsids. Endogenous Gag polypeptides and capsids can be used package cargo and/or deliver it to cells, for example, to package and/or deliver a nucleic acid molecule for use in gene editing, such as a component involved in a CRISPR-Cas system.
    Type: Grant
    Filed: July 21, 2021
    Date of Patent: November 22, 2022
    Assignee: VNV NEWCO INC.
    Inventors: Colin Malone, Ian Peikon, Zachary Gilbert, Andrey Pisarev, Adam Fraites, Jessica Crisp
  • Endogenous Gag-based capsids and uses thereof
    Patent number: 11447527
    Abstract: Disclosed herein, in certain embodiments, are recombinant Arc and endogenous Gag polypeptides, and methods of using recombinant Arc and endogenous Gag polypeptides.
    Type: Grant
    Filed: July 21, 2021
    Date of Patent: September 20, 2022
    Assignee: VNV NEWCO INC.
    Inventors: Colin Malone, Ian Peikon, Zachary Gilbert, Andrey Pisarev, Adam Fraites, Jessica Crisp
  • ARC-BASED CAPSIDS AND USES THEREOF
    Publication number: 20220088224
    Abstract: Disclosed herein, in certain embodiments, are recombinant Arc and endogenous Gag polypeptides, and methods of using recombinant Arc and endogenous Gag polypeptides.
    Type: Application
    Filed: September 18, 2019
    Publication date: March 24, 2022
    Inventors: Colin MALONE, Ian PEIKON, Zachary GILBERT, Andrey PISAREV, Adam FRAITES, Jessica CRISP
  • ARC-BASED CAPSIDS AND USES THEREOF
    Publication number: 20220016032
    Abstract: Disclosed herein, in certain embodiments, are recombinant Arc and endogenous Gag polypeptides, and methods of using recombinant Arc and endogenous Gag polypeptides.
    Type: Application
    Filed: October 8, 2021
    Publication date: January 20, 2022
    Inventors: Colin MALONE, Ian PEIKON, Zachary GILBERT, Andrey PISAREV, Adam FRAITES, Jessica CRISP
  • ARC-BASED CAPSIDS AND USES THEREOF
    Publication number: 20220002358
    Abstract: Disclosed herein, in certain embodiments, are recombinant Arc and endogenous Gag polypeptides, and methods of using recombinant Arc and endogenous Gag polypeptides.
    Type: Application
    Filed: July 21, 2021
    Publication date: January 6, 2022
    Inventors: Colin MALONE, Ian PEIKON, Zachary Gilbert, Andrey Pisarev, Adam Fraites, Jessica Crisp
  • ARC-BASED CAPSIDS AND USES THEREOF
    Publication number: 20210403907
    Abstract: Disclosed herein, in certain embodiments, are recombinant Arc and endogenous Gag polypeptides, and methods of using recombinant Arc and endogenous Gag polypeptides.
    Type: Application
    Filed: September 13, 2021
    Publication date: December 30, 2021
    Inventors: Colin MALONE, Ian PEIKON, Zachary GILBERT, Andrey PISAREV, Adam FRAITES, Jessica CRISP
  • ARC-BASED CAPSIDS AND USES THEREOF
    Publication number: 20210347829
    Abstract: Disclosed herein, in certain embodiments, are recombinant Arc and endogenous Gag polypeptides, and methods of using recombinant Arc and endogenous Gag polypeptides.
    Type: Application
    Filed: July 21, 2021
    Publication date: November 11, 2021
    Inventors: Colin MALONE, Ian PEIKON
  • Vaccine compositions comprising endogenous Gag polypeptides
    Patent number: 11129892
    Abstract: Described herein is a composition comprising: 1) an ARC polypeptide or an endogenous gag (endo-gag) polypeptide; 2) a pathogen-associated antigen; and 3) an adjuvant. Also described herein are vaccines and methods of vaccination using compositions comprising: 1) an ARC polypeptide or an endogenous gag (endo-gag) polypeptide; 2) a pathogen-associated antigen; and 3) an adjuvant.
    Type: Grant
    Filed: May 18, 2020
    Date of Patent: September 28, 2021
    Assignee: VNV NEWCO INC.
    Inventors: Zachary Gilbert, Colin Malone