Patents by Inventor Colin Martin McKee

Colin Martin McKee has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NOVEL ROR1 ANTIBODY IMMUNOCONJUGATES
    Publication number: 20230293712
    Abstract: Provided herein are immunoconjugates comprising an anti-ROR1 antibody or an antigen-binding fragment thereof and an exatecan moiety or an analog thereof. These immunoconjugates are useful for treating ROR1-expressing cancers.
    Type: Application
    Filed: July 8, 2021
    Publication date: September 21, 2023
    Applicant: Velosbio Inc.
    Inventors: Brian Lannutti, Katti Jessen, Xin Guo, Mira Ko, Jeffry D. Watkins, Stephanie Louise Johnson, Colin Martin McKee
  • METHOD OF SYNTHESIZING OF ANTIBODY CONJUGATES USING AFFINITY RESINS
    Publication number: 20170354744
    Abstract: Disclosed is a solid phase method of synthesising biomolecule-effector-conjugates and biomolecule-reporter-conjugates. In particular, this invention relates to a solid phase method of synthesising antibody-effector-conjugates and antibody-reporter conjugates. This invention also relates to intermediate methods of producing immobilised, chemically modified biomolecules, e.g., antibodies.
    Type: Application
    Filed: October 27, 2015
    Publication date: December 14, 2017
    Inventors: David John Evans, Colin Martin McKee
  • METHOD OF SYNTHESIZING ANTIBODY DRUG CONJUGATES USING AFFINITY RESINS
    Publication number: 20170326251
    Abstract: Disclosed is a solid phase method of synthesizing biomolecule-drug-conjugates. In particular, this invention relates to a solid phase method of synthesizing antibody-drug-conjugates (ADCs). This invention also relates to intermediate methods of producing immobilized, chemically modified biomolecules, e.g., antibodies.
    Type: Application
    Filed: October 27, 2015
    Publication date: November 16, 2017
    Inventors: David John Evans, Colin Martin McKee
  • METHOD OF SYNTHESISING ADCS USING PHOTOCLEAVABLE LINKERS ON SOLID SUPPORT
    Publication number: 20170196990
    Abstract: Disclosed is a solid phase method of synthesising biomolecule-drug-conjugates (e.g. antibody-drug-conjugates) using photocleavable moieties. The method comprises: (i) providing an immobilised photocleavable group-biomolecule conjugate; (ii) optionally contacting the immobilised photocleavable group-biomolecule conjugate with a chemical modification agent or activating agent to provide an immobilised photocleavable group-biomolecule conjugate that is chemically modified or activated at the biomolecule portion; (iii) contacting the immobilised photocleavable group-biomolecule conjugate of step (i) or the chemically modified or activated immobilised photocleavable group-biomolecule conjugate of step (ii) with a drug component to form an immobilised photocleavable group-biomolecule-drug-conjugate; and (iv) irradiating the immobilised photocleavable group-biomolecule-drug-conjugate of step (iii) with radiation thereby releasing the biomolecule-drug-conjugate.
    Type: Application
    Filed: July 8, 2015
    Publication date: July 13, 2017
    Inventors: Charles Ian Robert Johnson, Sara Louise Jenkins, Colin Martin McKee, David John Evans
  • Methods for production of recombinant polypeptides
    Publication number: 20020146779
    Abstract: Methods for the production of peptides with authentic N-terminal are provided. DNA constructs are also described, which can be used in the production of transgenic animals, which produce the desired peptide in their milk.
    Type: Application
    Filed: December 21, 2000
    Publication date: October 10, 2002
    Inventors: Ian Robert Cottingham, Colin Martin McKee, Alan Robert Miller