Patents by Inventor Colin Maurice Casimir

Colin Maurice Casimir has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of Making Viral Particles Having a Modified Cell Binding Activity and Uses Thereof
    Publication number: 20110020901
    Abstract: The present invention relates to a method for packaging viral particles such that one or more peptides on the surface of the virus particle are derived from the packaging cell. By incorporating certain peptides it is possible to target viral particles to specific cell types. Such a system is of use, for example, in gene therapy treatments.
    Type: Application
    Filed: June 23, 2010
    Publication date: January 27, 2011
    Inventor: Colin Maurice Casimir
  • Materials and methods relating to the transfer of nucleic acid into quiescent cells
    Publication number: 20040161849
    Abstract: Materials and methods for transferring nucleic acid encoding a polypeptide for treating a disease or disorder into populations of quiescent cells such as haematopoietic stem cells (HSCs), using retroviral packaging cell lines and retroviral particles expressing and displaying a growth factor such as stem cell factor (SCF) on the cell surface or as a fusion with a viral envelope protein. The present invention also relates compositions comprising the retroviral packaging cell lines and viral particles, and their use in methods of medical treatment, in vivo and ex vivo.
    Type: Application
    Filed: February 17, 2004
    Publication date: August 19, 2004
    Applicant: Mayo Foundation For Medical Education and Research, a Minnesota corporation
    Inventors: Stephen James Russell, Adele Kay Fielding, Colin Maurice Casimir
  • Materials and methods relating to the transfer of nucleic acid into quiescent cells
    Patent number: 6723561
    Abstract: Materials and methods for transferring nucleic acid encoding a polypeptide for treating a disease or disorder into populations of quiescent cells such as haematopoietic stem cells (HSCs), using retroviral packaging cell lines and retroviral particles expressing and display a growth factor such as stem cell factor (SCF) on the cell surface or as a fusion with a viral envelope protein. The present invention also relates to compositions comprising the retroviral packaging cell lines and retroviral particles, and their use in methods of medical treatment, in vivo and ex vivo.
    Type: Grant
    Filed: October 5, 1998
    Date of Patent: April 20, 2004
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Stephen James Russell, Adele Kay Fielding, Colin Maurice Casimir
  • MATERIALS AND METHODS RELATING TO THE TRANSFER OF NUCLEIC ACID INTO QUIESCENT CELLS
    Publication number: 20030007952
    Abstract: Materials and methods for transferring nucleic acid encoding a polypeptide for treating a disease or disorder into populations of quiescent cells such as haematopoietic stem cells (HSCs), using retroviral packaging cell lines and retroviral particles expressing and displaying a growth factor such as stem cell factor (SCF) on the cell surface or as a fusion with a viral envelope protein. The present invention also relates to compositions comprising the retroviral packaging cell lines and retroviral particles, and their use in methods of medical treatment, in vivo and ex vivo.
    Type: Application
    Filed: October 5, 1998
    Publication date: January 9, 2003
    Inventors: STEPHEN JAMES RUSSELL, ADELE KAY FIELDING, COLIN MAURICE CASIMIR