Patents by Inventor Colin Mill Archer

Colin Mill Archer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Chelator conjugates
    Patent number: 8852550
    Abstract: The present invention relates to improved chelator conjugates with biological targeting molecules, suitable for forming metal complexes with radiometals. The radiometal complexes, especially with the radiometal 99mTc, are useful as radiopharmaceuticals.
    Type: Grant
    Filed: October 1, 2009
    Date of Patent: October 7, 2014
    Assignee: GE Healthcare Limited
    Inventors: Colin Mill Archer, Harry John Wadsworth, Torgrim Engell
  • Peptide-based compounds
    Patent number: 8299030
    Abstract: The invention relates to new peptide-based compounds for use as diagnostic imaging agents or as therapeutic agents wherein the agents comprise targeting vectors which bind to integrin receptors.
    Type: Grant
    Filed: August 8, 2011
    Date of Patent: October 30, 2012
    Assignee: GE Healthcare Limited
    Inventors: Alan Cuthbertson, Bard Indrevoll, Magne Solbakken, Torgrim Engell, Colin Mill Archer, Harry John Wadsworth
  • PEPTIDE-BASED COMPOUNDS
    Publication number: 20120020882
    Abstract: The invention relates to new peptide-based compounds for use as diagnostic imaging agents or as therapeutic agents wherein the agents comprise targeting vectors which bind to integrin receptors.
    Type: Application
    Filed: August 8, 2011
    Publication date: January 26, 2012
    Applicant: GE HEALTHCARE AS
    Inventors: Alan Cuthbertson, Bard Indrevoll, Magne Solbakken, Torgrim Engell, Colin Mill Archer, Harry John Wadsworth
  • Peptide-based compounds
    Patent number: 7994134
    Abstract: The invention relates to new peptide-based compounds for use as diagnostic imaging agents or as therapeutic agents wherein the agents comprise targeting vectors which bind to integrin receptors.
    Type: Grant
    Filed: April 15, 2009
    Date of Patent: August 9, 2011
    Assignee: GE Healthcare AS
    Inventors: Alan Cuthbertson, Bård Indrevoll, Magne Solbakken, Torgrim Engell, Colin Mill Archer, Harry John Wadsworth
  • CHELATOR CONJUGATES
    Publication number: 20100040542
    Abstract: The present invention relates to improved chelator conjugates with biological targeting molecules, suitable for forming metal complexes with radiometals. The radiometal complexes, especially with the radiometal 99mTc, are useful as radiopharmaceuticals.
    Type: Application
    Filed: October 1, 2009
    Publication date: February 18, 2010
    Applicant: GE HEALTHCARE LIMITED
    Inventors: COLIN MILL ARCHER, HARRY JOHN WADSWORTH, TORGRIM ENGELL
  • Chelator conjugates
    Patent number: 7597875
    Abstract: The present invention relates to improved chelator conjugates with biological targeting molecules, suitable for forming metal complexes with radiometals. The radiometal complexes, especially with the radiometal99mTc, are useful as radiopharmaceuticals.
    Type: Grant
    Filed: July 10, 2002
    Date of Patent: October 6, 2009
    Assignee: GE Healthcare Limited
    Inventors: Colin Mill Archer, Harry John Wadsworth, Torgrim Engell
  • Peptide-based Compounds
    Publication number: 20090203584
    Abstract: The invention relates to new peptide-based compounds for use as diagnostic imaging agents or as therapeutic agents wherein the agents comprise targeting vectors which bind to integrin receptors.
    Type: Application
    Filed: April 15, 2009
    Publication date: August 13, 2009
    Inventors: Alan Cuthbertson, Bard Indrevoll, Magne Solbakken, Torgrim Engell, Colin MIll Archer, Harry John Wadsworth
  • Peptide-based compounds
    Patent number: 7521419
    Abstract: The invention relates to new peptide-based compounds for use as diagnostic imaging agents or as therapeutic agents wherein the agents comprise targeting vectors which bind to integrin receptors.
    Type: Grant
    Filed: January 8, 2004
    Date of Patent: April 21, 2009
    Assignee: GE Healthcare AS
    Inventors: Alan Cuthbertson, Bard Indrevoll, Magne Solbakken, Torgrim Engell, Colin Mill Archer, Harry John Wadsworth
  • Chelator conjugates
    Publication number: 20040258619
    Abstract: The present invention relates to improved chelator conjugates with biological targeting molecules, suitable for forming metal complexes with radiometals. The radiometal complexes, especially with the radiometal99mTc, are useful as radiopharmaceuticals.
    Type: Application
    Filed: June 21, 2004
    Publication date: December 23, 2004
    Inventors: Colin Mill Archer, Harry John Wadsworth, Torgrim Engell
  • Metal chelating compounds having an SNNN donor set
    Patent number: 6004531
    Abstract: Ligands for radiopharmaceutical use are capable of chelating radiometal species and of being bound to biological targeting molecules. The ligands have formula (a) and (b), where A, A'=--SZ or Y, B.dbd.O or S, Y.dbd. (c), Z.dbd.H or a thiol protecting group, m=2 or 3, n=2 or 3, q=0 or 1, R.dbd.H or unsubstituted or substituted hydrocarbon and pharmaceutically acceptable salts, provided that at least one CR.sub.2 group represents CO and forms, together with an adjacent N atom, a --CONR-- amide group.
    Type: Grant
    Filed: August 26, 1997
    Date of Patent: December 21, 1999
    Assignee: Nycomed Amersham plc
    Inventors: Colin Mill Archer, Gary Robert Bower, Harjit Kaur Gill, Anthony Leonard Mark Riley, Anthony Eamon Storey, Lewis Reuben Canning, David Vaughan Griffiths
  • Radiometal complexes that localise in hypoxic tissue
    Patent number: 5997843
    Abstract: Methods of imaging and radiotherapy of hypoxic tissues are provided using radiometal complexes not substituted by a hypoxia-localizing moiety.
    Type: Grant
    Filed: April 9, 1996
    Date of Patent: December 7, 1999
    Assignee: Amersham International PLC
    Inventors: Colin Mill Archer, James Frederick Burke, Lewis Reuben Canning, Barbara Edwards, Adam Charles King
  • Metal-oxime chelates for use as radiopharmaceutical agents
    Patent number: 5993774
    Abstract: Novel metal chelating compounds, and radiometal, e.g., technetium-99m complexes thereof. The compounds can be used to radiolabel small biologically active species with minimal effect on their biodistribution and activity. The compounds have formula (a) or (b): ##STR1## where Z is (CR.sub.2).sub.n or (CR).sub.n, n is 2 or 3, X is a ligand comprising S, N or O, each R is H or C1-C20 substituted or unsubstituted hydrocarbon group, provided that 1-3 CR.sub.2 groups represent a CO (amide) moiety, and provided that 1-3 R may each comprise a targeting group and/or a protein reactive functionality.
    Type: Grant
    Filed: May 9, 1995
    Date of Patent: November 30, 1999
    Assignee: Amersham International plc
    Inventors: Colin Mill Archer, Lewis Reuben Canning, Harjit Kaur Gill, Anthony Leonard Mark Riley
  • Thioether-containing metal chelating compounds
    Patent number: 5932707
    Abstract: Ligands for radiopharmaceutical use are capable of chelating radiometal species and of being bound to biological targeting molecules. The ligands have the formula (a) and (b), where A, A'=--SZ or Y, B=O or S, Y=(c), Z=H or a thiol protecting group, m=2 or 3, n=2 or 3, q=0 or 1, R=H or unsubstituted or substituted hydrocarbon and pharmaceutically acceptable salts, provided that at least one CR.sub.2 group represents CO and forms, together with an adjacent N atom; a --CONR-- amide group.
    Type: Grant
    Filed: July 7, 1997
    Date of Patent: August 3, 1999
    Assignee: Nycomed Amersham plc
    Inventors: Colin Mill Archer, Gary Robert Bower, Harjit Kaur Gill, Anthony Leonard Mark Riley, Anthony Eamon Storey, Lewis Reuben Canning, David Vaughan Griffiths