Abstract: A device for dispensing fluid from a flexible bag includes a casing containing a tray for receiving a fluid-filled bag and a pressure applicator movable by an actuator. Movement of the actuator pushes the pressure applicator against the tray by translation or by rotation to compress the bag between the tray and the casing.

Abstract: A labelling tie (10) includes a tie portion (14), a wire assembly (24), and a bib portion (16) connected to the tie portion. The tie portion (10) has a first arm (18-R), a mid-segment, and a second arm (18-L). Spaced apart perforations (20) intersect each of the first and second arms. The wire assembly (24) has a retention wire (26) that spans across the first arm, the mid-segment, and the second arm. A sheet of labelling ties (62) includes separably connected labelling ties. A method attaches a labelling tie to an item or a group of items. The method includes wrapping the first arm (18-R) and second arm (18-L) around at least one object (12, 12?), allowing the first and second arms to meet at a location with a portion of the first arm and a portion of the second arm extending past the location, and twisting the first and second arm portions together, thereby securing the tie portion around the object(s).

Abstract: An apparatus (100, 200, 400, 500, 600) includes a stack (110, 310) having a plurality of connected tie web sheets (106, 306) and an image (114) disposed on each of the tie web sheets (106, 306), wherein the image (114) is the same on each tie web sheet (106, 306) and is disposed in overlay registration from sheet (106, 306) to sheet (106, 306). Each tie web sheet (106, 306) includes a plurality of twist ties (104, 304), each twist tie (104, 304) having a proximal end (118) and a distal end (120), each twist tie (104, 304) being removably attached to the stack (110, 310) at its proximal end (118). A method of dispensing a plurality of twist ties (104, 304) includes mounting a stack (110, 310) within reach of a user and displaying an image (114) disposed on each of the tie web sheets (106, 306). Removal of a twist tie (104, 304) of the plurality of twist ties (104, 304) of the stack (110, 310) does not alter the image (114) viewable by the user.

Abstract: A computerized system and techniques facilitate the monitoring and management of online behaviorally-targeted advertising. In certain embodiments, electronic notifications related to advertising practices of members of an online advertising ecosystem are presented to users based on the discovery of elements of online content aimed at delivering targeted advertising messages to viewers of the content.

Abstract: A waterborne coating composition includes an aqueous polyurethane resin, a reactive silicone component, and a crosslinker. The aqueous polyurethane resin can have urethane linkages, hydrazinecarboxamide linkages, and reactive hydrazide functional groups. The polyurethane resin can have a glass transition temperature of less than 25° C. Methods of preparing waterborne coating compositions and substrates at least partially coated with waterborne coating compositions are also disclosed.

Abstract: Methods and apparatus are provided for causing the incorrect operation (‘faults’) of digital devices such as embedded computer systems or integrated circuits. The apparatus uses a switching element to cause perturbations on the power supplies of the digital device. This apparatus can be connected to existing embedded systems with a minimal of modifications, and can insert a variety of faults into those embedded systems. Such faults can be used for verification of fault-tolerant systems or algorithms, including both safety-critical designs and cryptographic designs.

Abstract: A tie article that includes an attachment portion and a bib portion, where the bib portion includes at least one arm segment and at least one closure device (e.g., a retention wire, tin tie, clasp tie, and the like), where the attachment portion and the bib portion are integrally fabricated from a printed sheet having a first surface and a polymeric film adhered to the first surface of the printed sheet such that the closure device(s) is disposed between the first surface of the printed sheet and the polymeric film at the attachment portion. Multiple tie articles may be manufactured with an in-line process.

Abstract: A tie article that includes an attachment portion and a bib portion, where the bib portion includes at least one arm segment and at least one closure device (e.g., a retention wire, tin tie, clasp tie, and the like), where the attachment portion and the bib portion are integrally fabricated from a printed sheet having a first surface and a polymeric film adhered to the first surface of the printed sheet such that the closure device(s) is disposed between the first surface of the printed sheet and the polymeric film at the attachment portion. Multiple tie articles may be manufactured with an in-line process.

Abstract: Methods and apparatus are provided for causing the incorrect operation (‘faults’) of digital devices such as embedded computer systems or integrated circuits. The apparatus uses a switching element to cause perturbations on the power supplies of the digital device. This apparatus can be connected to existing embedded systems with a minimal of modifications, and can insert a variety of faults into those embedded systems. Such faults can be used for verification of fault-tolerant systems or algorithms, including both safety-critical designs and cryptographic designs.

Abstract: Disclosed are chemical entities which are inhibitors of spleen tyrosine kinase (SYK), namely, chemical entities comprising 6-((1R,2S)-2-aminocyclohexylamino)-7-fluoro-4-(1-methyl-1H-pyrazol-4-yl)-1H-pyrrolo[3,4-c]pyridine-3(2H)-one and certain solid state forms thereof. Also disclosed are methods of using the chemical entities to treat disorders such as a cancer.

Abstract: A computerized system and techniques facilitate the monitoring and management of online behaviorally-targeted advertising. In certain embodiments, electronic notifications related to advertising practices of members of an online advertising ecosystem are presented to users based on the discovery of elements of online content aimed at delivering targeted advertising messages to viewers of the content.

Abstract: A medical procedure localization aid produces reference marks on both the patient and the medical imaging scan. The aid is defined by a substrate sheet having indicia on one side that is opaque to medical imaging radiation and indicia on a second side that is transferable to a patient. The indicia on the first side is displayed on the scan image and the indicia on the second side is imprinted on the patient. By visualizing the location of a target on the scan image relative to the indicia on the scan image and comparing that with indicia on the patient, a medical professional may reliably locate where a medical procedure should be performed.

Abstract: The present invention relates to novel inhibitors of Factors VIIa, IXa, Xa, XIa, in particular Factor VIIa, pharmaceutical compositions comprising these inhibitors, and methods for using these inhibitors for treating or preventing thromboembolic disorders, cancer or rheumatoid arthritis. Processes for preparing these inhibitors are also disclosed.

Abstract: A waterborne coating composition includes an aqueous polyurethane resin, a reactive silicone component, and a crosslinker. The aqueous polyurethane resin can have urethane linkages, hydrazinecarboxamide linkages, and reactive hydrazide functional groups. The polyurethane resin can have a glass transition temperature of less than 25° C. Methods of preparing waterborne coating compositions and substrates at least partially coated with waterborne coating compositions are also disclosed.

Abstract: The present invention relates to compounds that are useful as inhibitors of the activity of one or more isoforms of the serine/threonine kinase, AKT. The present invention also relates to pharmaceutical compositions comprising these compounds and to methods of using these compounds in the treatment of cancer and methods of treating cancer.

Abstract: The present invention relates to compounds that are useful as inhibitors of the activity of one or more isoforms of the serine/threonine kinase, AKT. The present invention also relates to pharmaceutical compositions comprising these compounds and to methods of using these compounds in the treatment of cancer and methods of treating cancer.

Abstract: A method for determining the position and its statistical uncertainty of a fission semi-track in a crystal based on detecting the tip and etch figure of a fission semi-track in a series of transmitted light images. A computer software program for: detecting the tip and etch figure of a fission semi-track in a series of transmitted light images and assessing the viability of the tip using a scoring equation; writing to and loading from a computer database of fission semi-tracks; modifying the scoring equation for assessing fission semi-track tip viability based on the contents of the computer database. A computer database consisting of transmitted light images of fission semi-tracks. A method for determining the statistical probability that a fission semi-track is a real fission semi-track.

Abstract: A method for determining the position and its statistical uncertainty of a confined fission track in a crystal based on detecting confined fission track tips in a series of transmitted light images. A computer software program for: detecting confined fission track tips in a series of transmitted light images and assessing the viability of each tip using a scoring equation; writing to and loading from a computer database of confined fission tracks; modifying the scoring equation for assessing confined fission track tip viability based on the contents of the computer database. A computer database consisting of transmitted light images of confined fission tracks. A method for determining the statistical probability that a confined fission track is a real confined fission track.

Abstract: A tie article that includes an attachment portion and a bib portion, where the bib portion includes at least one arm segment and at least one closure device (e.g., a retention wire, tin tie, clasp tie, and the like), where the attachment portion and the bib portion are integrally fabricated from a printed sheet having a first surface and a polymeric film adhered to the first surface of the printed sheet such that the closure device(s) is disposed between the first surface of the printed sheet and the polymeric film at the attachment portion. Multiple tie articles may be manufactured with an in-line process.

Abstract: The present invention relates to novel inhibitors of Factors VIIa, IXa, Xa, XIa, in particular Factor VIIa, pharmaceutical compositions comprising these inhibitors, and methods for using these inhibitors for treating or preventing thromboembolic disorders, cancer or rheumatoid arthritis. Processes for preparing these inhibitors are also disclosed.